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Outcomes of a staged surgical treatment strategy for aortoesophageal fistula

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Abstract

Background

Evolution of thoracic endovascular aortic repair (TEVAR) appears to have influenced the pathogenesis and treatment strategy for aortoesophageal fistula (AEF). The purposes of this study are to evaluate our current surgical strategy for AEF and to provide insight to further improve the prognosis of such a devastating condition.

Methods and results

Between 2005 and 2013, we retrospectively reviewed the clinical charts of 10 patients requiring surgical treatment for AEF in Tohoku University Hospital. Four cases were primary and 6 were secondary. Initially, bridging TEVAR to control bleeding with concomitant subtotal esophagectomy and complete debridement of infected mediastinal tissue was performed. After a short interval, the patients underwent in situ aortic replacement with cryopreserved homografts or rifampicin-bonded Dacron grafts with omentopexy. Esophageal reconstruction was planned following general physical status improvement after 3–6 months. In-hospital mortality in the acute phase was 30 %. Although the completion of the staged strategy achieving successful esophageal reconstruction was possible in 5 patients, no local relapses of infection were observed in these patients. Overall survival at 1 and 5 year were 68.6 and 42.9 %, respectively.

Conclusions

The staged surgical treatment strategy for AEF consisted of prompt TEVAR to control bleeding with concomitant subtotal esophagectomy and subsequent in situ reconstruction of the aorta with an aortic homograft. This procedure enabled us to control local mediastinal infection with acceptable mortality. Avoiding delay in the diagnosis and initial treatment and resolving complications at each treatment step should further improve AEF treatment.

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References

  1. Marone EM, Coppi G, Kahlberg A, Tshomba Y, Chiesa R. Combined endovascular and surgical treatment of primary aortoesophageal fistula. Tex Heart Inst J. 2010;37:722–4.

    PubMed Central  PubMed  Google Scholar 

  2. Iguchi A, Miyazaki S, Akimoto H, Ohmi M, Tabayashi K. Successful management of secondary aortoesophageal fistula with graft infection. Thorac Cardiovasc Surg. 2001;49:126–8.

    Article  CAS  PubMed  Google Scholar 

  3. Kawamoto S, Saiki Y, Oda K, Nitta N, Akasaka J, Miyazaki S, et al. Successful management of esophagoparaprosthetic fistula after aortic surgery. Ann Thorac Surg. 2008;85:1449–51.

    Article  PubMed  Google Scholar 

  4. Canaud L, Ozdemir BA, Bee WW, Bahia S, Holt P, Thompson M. Thoracic endovascular aortic repair in management of aortoesophageal fistulas. J Vasc Surg. 2014;59:248–54.

    Article  PubMed  Google Scholar 

  5. Peck JJ, Eidemiller LR. Aortoenteric fistulas. Arch Surg. 1992;127:1191–3.

    Article  CAS  PubMed  Google Scholar 

  6. Hageman JH, Nein AG, Davis JT. Primary aortoesophageal fistula caused by an atherosclerotic thoracoabdominal aortic aneurysm: a case report and review of the literature. Cardiovasc Surg. 1995;3:495–9.

    Article  CAS  PubMed  Google Scholar 

  7. Von Segesser LK, Tkebuchava T, Niederhäuser U, Künzli A, Lachat M, Genoni M, et al. Aortobronchial and aortoesophageal fistulae as risk factors in surgery of descending thoracic aortic aneurysms. Eur J Cardiothorac Surg. 1997;12:195–201.

    Article  Google Scholar 

  8. Saito A, Motomura N, Hattori O, Kinoshita O, Shimada S, Saiki Y, et al. Outcome of surgical repair of aorto-eosophageal fistulas with cryopreserved aortic allografts. Interact Cardiovasc Thorac Surg. 2012;14:532–7.

    Article  PubMed Central  PubMed  Google Scholar 

  9. Inoue T, Nishino T, Peng YF, Saga T. Successful one-stage operation of aortoesophageal fistula from thoracic aneurysm using a rifampicin-soaked synthetic graft. Interact CardioVasc Thorac Surg. 2008;7:322–4.

    Article  PubMed  Google Scholar 

  10. Kubota S, Shiiya N, Shingu Y, Wakasa S, Ooka T, Tachibana T, et al. Surgical strategy for aortoesophageal fistula in the endovascular era. Gen Thorac Cardiovasc Surg. 2013;61:560–4.

    Article  PubMed  Google Scholar 

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Acknowledgments

The authors would present profound thanks to Dr. Noboru Motomura in University of Tokyo Tissue Bank for providing cryopreserved aortic homografts, and gratefully acknowledge helpful discussions with Dr. Toru Nakano in Division of Advanced Surgical Science and Technology, Tohoku University Graduate School of Medicine.

Conflict of interest

The authors have declared that no conflict of interest exists.

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Correspondence to Shunsuke Kawamoto.

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Kawamoto, S., Sato, M., Motoyoshi, N. et al. Outcomes of a staged surgical treatment strategy for aortoesophageal fistula. Gen Thorac Cardiovasc Surg 63, 147–152 (2015). https://doi.org/10.1007/s11748-014-0472-0

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  • DOI: https://doi.org/10.1007/s11748-014-0472-0

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