Skip to main content

Advertisement

SpringerLink
Log in

Pulmonary carcinosarcoma with an osteosarcomatous component

  • Case Report
  • Published:
General Thoracic and Cardiovascular Surgery Aims and scope Submit manuscript

Abstract

Pulmonary carcinosarcoma is a rare disease entity defined as a neoplasm, which has biphasic features consisting of both epithelial and sarcomatous components. It has been reported that the most frequent epithelial component is squamous cell carcinoma, while the most frequent sarcomatous component is rhabdomyosarcoma. Pulmonary carcinosarcomas with osteosarcoma components are even rarer. We report a case of a potentially curative resection for carcinosarcoma with an osteosarcoma component. Thoracic surgeons should be aware of this rare tumor when lung tumors with ossification are encountered.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4

Similar content being viewed by others

References

  1. World Health Organization Histological typing of lung and pleural tumours. 4th ed. Lyon: IARCPress; 2004.

  2. Brambilla E, Travis WD, Colby TV, Corrin B, Shimosato Y. The new World Health Organization classification of lung tumours. Eur Respir J. 2001;18:1059–68.

    Article  PubMed  CAS  Google Scholar 

  3. Koss MN, Hochholzer L, Frommelt RA. Carcinosarcomas of the lung: a clinicopathologic study of 66 patients. Am J Surg Pathol. 1999;23:1514–26.

    Article  PubMed  CAS  Google Scholar 

  4. Kim KI, Flint JD, Muller NL. Pulmonary carcinosarcoma: radiologic and pathologic findings in three patients. AJR Am J Roentgenol. 1997;169:691–4.

    PubMed  CAS  Google Scholar 

  5. Huwer H, Kalweit G, Straub U, Feindt P, Volkmer I, Gams E. Pulmonary carcinosarcoma: diagnostic problems and determinants of the prognosis. Eur J Cardiothorac Surg. 1996;10:403–7.

    Article  PubMed  CAS  Google Scholar 

  6. Dacic S, Finkelstein SD, Sasatomi E, Swalsky PA, Yousem SA. Molecular pathogenesis of pulmonary carcinosarcoma as determined by microdissection-based allelotyping. Am J Surg Pathol. 2002;26:510–6.

    Article  PubMed  Google Scholar 

  7. Pardo J, Aisa G, Alava E, Sola JJ, Panizo A, Rodriguez-Spiteri N, et al. Primary mixed squamous carcinoma and osteosarcoma (carcinosarcomas) of the lung have a CGH mapping similar to primitive squamous carcinomas and osteosarcomas. Diagn Mol Pathol. 2008;17:151–8.

    Article  PubMed  CAS  Google Scholar 

  8. Petrov DB, Vlassov VI, Kalaydjiev GT, Plochev MA, Obretenov ED, Stanoev VI, et al. Primary pulmonary sarcomas and carcinosarcomas—postoperative results and comparative survival analysis. Eur J Cardiothorac Surg. 2003;23:461–6.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of General Thoracic Surgery, Osaka Prefectural Medical Center for Respiratory and Allergic Diseases, 3-7-1 Habikino, Habikino, Osaka, 583-8588, Japan

    Ryu Kanzaki, Naoki Ikeda, Eiji Okura, Naoto Kitahara & Mitsunori Ohta

  2. Department of Pathology, Osaka Prefectural Medical Center for Respiratory and Allergic Diseases, 3-7-1 Habikino, Habikino, Osaka, 583-8588, Japan

    Akira Okimura & Kunimitsu Kawahara

Authors
  1. Ryu Kanzaki
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Naoki Ikeda
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Eiji Okura
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Naoto Kitahara
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Akira Okimura
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Kunimitsu Kawahara
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Mitsunori Ohta
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Ryu Kanzaki.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kanzaki, R., Ikeda, N., Okura, E. et al. Pulmonary carcinosarcoma with an osteosarcomatous component. Gen Thorac Cardiovasc Surg 60, 855–858 (2012). https://doi.org/10.1007/s11748-012-0098-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11748-012-0098-z

Keywords

Search

Navigation