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Off-pump coronary artery bypass grafting with an aortic nonclamping technique may reduce the incidence of cerebral complications

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Abstract

Purpose

Cerebrovascular accidents after coronary artery bypass grafting (CABG) remain a complication despite the advancements in techniques. Aortic partial clamping should be avoided to prevent this cerebral complication. We use pedicle arterial grafts (bilateral internal-mammary arteries and the right gastroepiploic artery) and saphenous vein graft with a proximal anastomosis device for off-pump CABG without aortic partial clamping. We call this technique the aortic nonclamping technique.

Methods

Between 2001 and 2007, a total of 468 patients underwent coronary bypass operations; 8 who were operated on with cardiopulmonary bypass were excluded from this study. Altogether, 451 patients underwent off-pump CABG using the aortic nonclamping technique. Among the procedures, 354 were performed using pedicle arterial grafts alone, and 99 were done using a saphenous vein graft with a proximal anastomosis device. Nine were performed with aortic partial clamping for any reason. Postoperative cerebral complications, especially cerebral infarction, were analyzed.

Results

Cerebral infarction occurred in two cases (0.47%) in the aortic nonclamping group. They were delayed in both cases, one occurring on the third day after operation and the other on the fourth day. One patient in the aortic clamping group had an intraoperative (early) cerebral infarction.

Conclusion

The aortic nonclamping technique might reduce the incidence of cerebral complications and produce ideal bypass grafts using arterial grafts and saphenous vein grafts with a proximal anastomosis device.

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References

  1. Calafiore AM, Di Mauro M, Teodori G, Di Gimmarco G, Cirmeni S, Contini M, et al. Impact of aortic manipulation on incidence of cerebrovascular accident after surgical myocardial revascularization. Ann Thorac Surg 2002;73:1387–1393.

    Article  PubMed  Google Scholar 

  2. Almassi GH, Sommers T, Moritz TE, Shroyer ALW, London MJ, Henderson WG, et al. Stroke in cardiac surgical patients: determinants and outcome. Ann Thorac Surg 1999;68:391–398.

    Article  PubMed  CAS  Google Scholar 

  3. Gaudino M, Glieca F, Alessandrini F, Nasso G, Pragliola C, Luciani N, et al. High risk coronary artery bypass patient: incidence, surgical strategies, and results. Ann Thorac Surg 2004;77:574–579.

    Article  PubMed  Google Scholar 

  4. Al-Ruzzeh S, Athanasiou T, George S, Glenville BE, De Souza AC, Pepper JR, et al. Is the use of cardiopulmonary bypass for multivessel coronary artery bypass surgery an independent predictor of operative mortality in patients with ischemic left ventricular dysfunction? Ann Thorac Surg 2003;76:444–451.

    Article  PubMed  Google Scholar 

  5. Blauth CI. Macroemboli and microemboli during cardiopulmonary bypass. Ann Thorac Surg 1995;59:1300–1303.

    Article  PubMed  CAS  Google Scholar 

  6. Kapetanakis EI, Stamou SC, Dullum MKC, Hill PC, Haile E, Boyce SW, et al. The impact of aortic manipulation on neurologic outcomes after coronary artery bypass surgery: a riskadjusted study. Ann Thorac Surg. 2004;78:1564–1571.

    Article  PubMed  Google Scholar 

  7. Kotoh K, Fukahara K, Doi T, Nagura S, Misaki T. Predictors of early postoperative cerebral infarction after isolated offpump coronary artery bypass grafting. Ann Thorac Surg 2007;83:1679–1683.

    Article  PubMed  Google Scholar 

  8. Peel GK, Stamou SC, Dullum MK, Hill PC, Jablonski KA, Bafl AS, et al. Chronologic distribution of stroke after mini mally invasive versus conventional coronary artery bypass. J Am Coll Cardiol 2004;43:752–756.

    Article  PubMed  Google Scholar 

  9. Bednar F, Osmancik P, Vanek T, Mocikova H, Jares M, Straka Z, et al. Platelet activity and aspirin efficacy after offpump compared with on-pump coronary artery bypass surgery: results from the prospective randomized trial PRAGUE 11-Coronary Artery Bypass and REactivity of Thrombocytes (CABARET). J Thorac Cardiovasc Surg 2008;136:1054–1060.

    Article  PubMed  Google Scholar 

  10. Puskas JD, Halkos ME, Balkhy H, Caskey M, Connolly M, Crouch J, et al. Evaluation of the PAS-Port proximal anastmosis system in coronary artery bypass surgery (the EPIC trial). J Thorac Cardiovasc Surg 2009;138:125–132.

    Article  PubMed  Google Scholar 

  11. Akipinar B, Guden M, Sagbas E, Sanisoglu I, Ergenoglu MU, Turkoglu C. Clinical experience with the Novare Enclose II manual proximal anastomotic device during off-pump coronary artery surgery. Eur J Cardiothorac Surg 2005;27:1070–1073.

    Article  Google Scholar 

  12. Medalion B, Meirson D, Hauptman E, Sasson L, Schachner A. Initial experience with the Heartstring proximal anastomotic system. J Thorac Cardiovasc Surg 2003;128:273–277.

    Google Scholar 

  13. Wolf LG, Abu-Omar Y, Choudhary BP, Piqott D, Taggart DP. Gaseous and solid cerebral microembolization during proximal aortic anastomoses in off-pump coronary surgery: the effect of an aortic side-biting clamp and two clampless devices. J Thorac Cardiovasc Surg 2007;133:485–493.

    Article  Google Scholar 

  14. Suma H, Tanabe H, Takahashi A, Horii T, Isomura T, Hirose H, et al. Twenty years experience with the gastroepiploic artery graft for CABG. Circulation 2007;116(suppl I):I188–I191.

    PubMed  Google Scholar 

  15. Gagliardotto P, Coste P, Lazreg M, Dor V. Skeltonized right gastroepiploic artery used for coronary artery bypass grafting. Ann Thorc Surg 1998;66:240–242.

    Article  CAS  Google Scholar 

  16. Asai T, Tabata S. Skeletonization of the right gastroepiploic artery using an ultrasonic scalpel. Ann Thorac Surg 2002;74:1715–1717.

    Article  PubMed  Google Scholar 

  17. Kamiya H, Watanabe G, Takemura H, Tomita S, Nagamine H, Kanamori T. Total arterial revascularization with composite skeletonized gastroepiploic artery graft in off-pump coronary artery bypass grafting. J Thorac Cardiovasc Surg 2004;127:1151–1157.

    Article  PubMed  Google Scholar 

  18. Ryu SW, Ahn BH, Choo SJ, Na KJ, Ahn YK, Jeon MH, et al. Skeltonized gastroepiploic artery as a composite graft for total arterial revascularization. Ann Thorac Surg 2005;80:118–123.

    Article  PubMed  Google Scholar 

  19. Nishida H, Tomizawa Y, Endo M, Kurosawa H. Survival benefit of exclusive use of in situ arterial conduits over combined use of arterial and vein grafts for multiple coronary artery bypass grafting. Circulation. 2005;112(suppl):I299–I303.

    PubMed  Google Scholar 

  20. Kobayashi J, Sasako Y, Bando K, Niwaya K, Tagusari O, Nakajima H, et al. Multiple off-pump coronary revascularization with “aorta no-touch” technique using composite and sequential methods. Heart Surg Forum 2002;5:114–118.

    PubMed  Google Scholar 

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Correspondence to Hiroshi Osawa.

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Osawa, H., Inaba, H., Kinoshita, O. et al. Off-pump coronary artery bypass grafting with an aortic nonclamping technique may reduce the incidence of cerebral complications. Gen Thorac Cardiovasc Surg 59, 681–685 (2011). https://doi.org/10.1007/s11748-011-0795-z

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  • DOI: https://doi.org/10.1007/s11748-011-0795-z

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