Skip to main content
Log in

Primary lung cancer arising from the wall of a giant bulla in which positron emission tomography was useful for preoperative diagnosis

  • Case Report
  • Published:
General Thoracic and Cardiovascular Surgery Aims and scope Submit manuscript

Abstract

We report a case of lung cancer arising from the wall of a giant bulla. A 58-year-old man consulted a physician because of bloody sputum. Chest computed tomography (CT) revealed a left upper giant bulla with partial thickness of the wall. Cytology of both sputum and transbronchial brushing was negative at that time. After 6 months follow-up CT scans showed more thickness of the wall, and positron emission tomography (PET) revealed high accumulation of fluorodeoxyglucose in the thickened wall. Because lung cancer was highly suspected, we performed an operation without a definitive diagnosis. The postoperative pathological diagnosis was large cell carcinoma arising from the wall of a giant bulla. Because a preoperative diagnosis is difficult in the case of lung carcinoma associated with bullous disease due to the lack of a characteristic radiological appearance and the difficulty of pathological examination, we emphasize that PET is a useful diagnostic tool.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Stoloff IL, Kanofsky P, Magilner L. The risk of lung cancer in males with bullous disease of the lung. Arch Environ Health 1971;22:163–167.

    CAS  PubMed  Google Scholar 

  2. Sato S, Asakura J, Suzuki H, Hirano J, Ohmori H, Takahisa K, et al. Study on surgical treatment for lung cancer associated with giant bullous disease. Jpn J Thorac Cardiovasc Surg 1998;46:260–266.

    Article  CAS  PubMed  Google Scholar 

  3. Hanaoka N, Tanaka F, Otake Y, Yanagihara K, Nakagawa T, Kawano Y, et al. Primary lung carcinoma arising from emphysematous bullae. Lung Cancer 2002;38:185–191.

    Article  PubMed  Google Scholar 

  4. Tsutsui M, Araki Y, Shirakusa T, Inutsuka S. Characteristic radiographic features of pulmonary carcinoma associated with large bulla. Ann Thorac Surg 1988;46:679–683.

    Article  CAS  PubMed  Google Scholar 

  5. Maki D, Takahashi M, Murata K, Sawai S, Fujino S, Inoue S. Computed tomography appearances of bronchogenic carcinoma associated with bullous lung disease. J Comput Assist Tomogr 2006;30:447–452.

    Article  PubMed  Google Scholar 

  6. Hirai S, Hamanaka Y, Mitsui N, Morifuji K, Sutoh M. Primary lung cancer arising from the wall of a giant bulla. Ann Thorac Cardiovasc Surg 2005;11:109–113.

    PubMed  Google Scholar 

  7. Mizuguchi S, Nishida T, Kawata Y, Izumi N, Nishiyama N, Inoue K. Synchronous double cancers developing from the wall of bullae in the bilateral lungs. Jpn J Thorac Cardiovasc Surg 2004;52:36–40.

    Article  PubMed  Google Scholar 

  8. Venuta F, Rendina EA, Pescarmona EO, De Giacomo T, Vizza D, Flaishman I, et al. Occult lung cancer in patients with bullous emphysema. Thorax 1997;52:289–290.

    Article  CAS  PubMed  Google Scholar 

  9. Ung YC, Maziak DE, Vanderveen JA, Smith CA, Gulenchyn K, Lacchetti C, et al. 18Fluorodeoxyglucose positron emission tomography in the diagnosis and staging of lung cancer: a systematic review. J Natl Cancer Inst 2007;99:1753–1767.

    Article  PubMed  Google Scholar 

  10. Berghmans T, Dusart M, Paesmans M, Hossein-Foucher C, Buvat I, Castaigne C, et al. Primary tumor standardized uptake value (SUVmax) measured on fluorodeoxyglucose positron emission tomography (FDG-PET) is of prognostic value for survival in non-small cell lung cancer (NSCLC): a systematic review and meta-analysis (MA) by the European Lung Cancer Working Party for the IASLC Lung Cancer Staging Project. J Thorac Oncol 2008;3:6–12.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Takeshi Yoshikawa.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Yoshikawa, T., Misao, T. & Aoe, M. Primary lung cancer arising from the wall of a giant bulla in which positron emission tomography was useful for preoperative diagnosis. Gen Thorac Cardiovasc Surg 59, 137–140 (2011). https://doi.org/10.1007/s11748-010-0618-7

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11748-010-0618-7

Key words

Navigation