Abstract
Although there are many reports of spontaneous regression of noninvasive thymoma, there are no reports of spontaneous regression of an invasive thymoma. Moreover, the mechanism of the spontaneous regression is still unknown. The present case concerns a 47-year-old man who presented with chest pain. Computed tomography (CT) showed a large anterior mediastinal mass with left pleural effusion that occluded the innominate vein. The tissue obtained by video-assisted thoracic surgery suggested a diagnosis of invasive thymic carcinoma. One month later CT showed prominent regression of the tumor, and the tumor was completely resected. On pathology, the diagnosis was thymoma type B3.
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References
Everson TC, Cole WH. Spontaneous regression of cancer. Philadelphia: Saunders; 1966. p. 88–163.
Cole WH. Efforts to explain spontaneous regression of cancer. J Surg Oncol 1981;17:201–209.
Carlson NLT. How frequent is spontaneous remission of neuroblastomas? Implications for screening. Br J Cancer 1990;61:41–46.
Moran CA, Suster S. Thymoma with prominent cystic and hemorrhagic changes and areas of necrosis and infarction: a clinicopathologic study of 25 case. Am J Surg Pathol 2001;25:1086–1090.
Vaideeswar P, Padmanabhan A, Deshpande JR, Pandit SP. Thymoma: a pathological study of 50 cases. Postgrad Med J 2004;50:94–97.
Kuo T. Sclerosing thymoma: a possible phenomenon of regression. Histopathology 1994;25:289–291.
Moran CA, Suster S. “Ancient” (sclerosing) thymomas: a clinicopathologic study of 10 cases. Am J Clin Pathol 2004;121:867–871.
References
Yutaka Y, Omasa M, Shikuma K, Okuda M, Taki T. Spontaneous regression of an invasive thymoma. Gen Thorac Cardiovasc Surg 2009;57:272–274
Ishibashi et al. Spontaneous regression of thymoma: report of a case. Kyobu Geka 2003;56:801.
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Yutaka, Y., Omasa, M., Shikuma, K. et al. Spontaneous regression of an invasive thymoma. Gen Thorac Cardiovasc Surg 57, 272–274 (2009). https://doi.org/10.1007/s11748-008-0366-0
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DOI: https://doi.org/10.1007/s11748-008-0366-0