The variation in the contents of sesamin and sesamolin was studied in oils extracted from 65 samples of sesame seeds (Sesamum indicum L.) from plants with shattering (n=29), semishattering (n=7), and nondehiscent (n=29) capsules. The oil content ranged from 32.5 to 50.6% and was greater in white than black seeds (P<0.001). The sesamin and sesamolin contents in seeds ranged from 7 to 712 mg/100 g (mean±SD, 163±141 mg/100 g) and from 21 to 297 mg/100 g (101±58 mg/100 g), respectively, with no difference between black and white seeds. Thus, there was a wide variation in the contents of sesamin and sesamolin, which were positively correlated (R 2=0.66, P<0.001). There were negative correlations between the contents of sesamin and the contents of sesaminol (R 2=0.37) and sesamolinol (R 2=0.36) and between the content of sesamolin and those of sesaminol (R 2=0.35) and sesamolinol (R 2=0.46) (P<0.001). Sesame seeds had an average of 0.63% lignans, making them a rich source of dietary lignans.
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Budowski, P., and K.S. Markley, The Chemical and Physiological Properties of Sesame Oil, Chem. Rev.. 48:125–151 (1951).
Hirose, N., T. Inoue, K. Nishihara, M. Sugano, K. Akimoto, S. Shimizu, and H. Yamada. Inhibition of Cholesterol Absorption and Synthesis in Rats by Sesamin, J. Lipid Res.. 32:629–638 (1991).
Chen, P.R., K.L. Chien, T.C. Su, C.J. Chang, T. Liu, H. Cheng, and C. Tsai, Dietary Sesame Reduces Serum Cholesterol and Enhances Antioxidant Capacity in Hypercholesterolemia, Nutr. Res. 25:559–567 (2005).
Lemcke-Norojärvi, M., A. Kamal-Eldin, L.Å Appelqvist, L.H. Dimberg, M. Öhrvall, and B. Vessby, Corn and Sesame Oils Increase Serum γ-Tocopherol Concentrations in Healthy Swedish Women, J. Nutr. 131:1195–1201 (2001).
Moazzami, A., R.E. Andersson, and A. Kamal-Eldin, HPLC Analysis of Sesaminol Glucosides in Sesame Seeds, J. Agric. Food Chem. 54:633–638 (2006).
Moazzami, A., R.E. Andersson, and A. Kamal-Eldin, Characterization and Analysis of Sesamolinol Diglucoside in Sesame Seeds, Biosci. Biotechnol. Biochem. 70:1478–1481 (2006).
Katsuzaki, H., M. Kawasumi, S. Kawakishi, and T. Osawa, Structure of Novel Antioxidative Lignan Glucosides Isolated from Sesame Seed, —Ibid. 56:2087–2088 (1992).
Kang, M., Y. Kawai, M. Naito, and T. Osawa, Dietary Defatted Sesame Flour Decreases Susceptibility to Oxidative Stress in Hypercholesterolemic Rabbits, J. Nutr. 129:1885–1890 (1999).
Kamal-Eldin, A., and L.-Å. Appelqvist, Variation in the Composition of Sterols, Tocopherols and Lignans in Seed Oils from Four Sesamum Species, J. Am. Oil Chem. Soc. 71:149–156 (1994).
Tashiro, T., Y. Fukuda, T. Osawa, and M. Namiki, Oil and Minor Components of Sesame (Sesamum indicum L.) Strains, —Ibid. 67:508–511 (1990).
Hemalatha, S., and Ghafoorunissa, Lignans and Tocopherols in Indian Sesame Cultivars, —Ibid. 81:467–470 (2004).
Yermanos, D.M., S. Hemstreet, W. Salleb, and C.K. Huszar, Oil Content and Composition of the Seed in the World Collection of Sesame Introductions, —Ibid. 49:20–23 (1972).
Fukuda, Y., T. Osawa, S. Kawagishi, and M. Namiki, Comparison of Contents of Sesamolin and Lignan Antioxidants in Sesame Seeds Cultivated in Japan, J. Jpn. Soc. Food Sci. Technol. [Nihon-Shokuhin-Kogyo-Gakkaishi] 35:483–486 (1988).
Beroza, M., and M.L. Kinman, Sesamin, Sesamolin and Sesamol Content of the Oil of Sesame as Affected by Strain, Location Grown, Ageing and Frost Damage, J. Am. Oil Chem. Soc. 32:348–350 (1955).
Crosby, G., Lignans in Food and Nutrition, Food Technol. 59:32–36 (2005).
Eliasson, C., A. Kamal-Eldin, R. Andersson, and P. Åman, High-Performance Liquid Chromatographic Analysis of Secoisolariciresinol Diglucoside and Hydroxycinnamic Acid Glucoside in Flaxseed by Alkaline Extraction, J. Chromatogr. A 1012:151–159 (2003).
Johansson, P., A. Kamal-Eldin, L.N. Lundgren, and P. Åman, HPLC Method for Analysis of Secoisolariciresinol Diglucoside in Flaxseeds, J. Agric. Food Chem. 48:5216–5219.
Appelqvist, L-Å., Further Studies on a Multisequential Method for Determination of Oil Content in Oil Seeds, J. Am. Oil Chem. Soc. 44:209–214 (1967).
Maechand, P.A., J. Zajicek, and N.G. Lewis, Oxygen Insertion in Sesamum indicum Furanofuran Lignans, Diastereoselective Synthesis of Enzyme Substrate Analogues, Can. J. Chem. 75:840–849 (1997).
Coulman, K.D., Z. Liu, W.Q. Hum, J. Michaelides, and L.U. Thompson, Whole Sesame Seed Is as Rich a Source of Mammalian Lignan Precursors as Whole Flaxseed, Nutr. Cancer 52:156–165 (2005).
Penalvo, J., S. Heinonen, A. Aura, and H. Adlercreutz, Dietary Sesamin Is Converted to Enterolactone in Human, J. Nutr. 135:1056–1062 (2005).
Frank, J., C. Eliasson, D. Leroy-Nivard, A. Budek, T. Lundh, B. Vessby, P. Åman, and A. Kamal-Eldin, Dietary Secoisolariciresinol Diglucoside and Its Oligomers with 3-Hydroxy-3-methyl-glutaric Acid Decrease Vitamin E Levels in Rats, Br. J. Nutr. 92:1–9 (2004).
Kamal-Eldin, A., D. Pettersson, and L. Appelqvist, Sesamin (a compound from sesame oil) Increases Tocopherol Levels in Rats Fed ad libitum, Lipids 30:499–505 (1995).
Yim, T.K., and K.M. Ko, Methylenedioxy Group and Cyclooctadiene Ring as Structural Determinates of Schisandrin in Protecting Against Myocardial Ischemia-Reperfusion Injury, Biochem. Pharmacol. 57:77–81 (1999).
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Moazzami, A.A., Kamal-Eldin, A. Sesame seed is a rich source of dietary lignans. J Amer Oil Chem Soc 83, 719 (2006). https://doi.org/10.1007/s11746-006-5029-7
- HPLC analysis
- lignan glucosides
- oil-soluble lignans
- sesame seeds