Journal of the American Oil Chemists' Society

, Volume 81, Issue 9, pp 873–877 | Cite as

Solubilization of lycopene in jojoba oil microemulsion

Article

Abstract

The unique properties of jojoba oil make it an essential raw material in the manufacture of cosmetics. New, totally dilutable U-type microemulsions of water, jojoba oil, alcohols, and the nonionic surfactant polyoxyethylene-10EO-oleyl alcohol (Brij 96V) have been formulated recently. Here, these microemulsions are shown to be capable of solubilizing lycopene, a nutraceutical insoluble in water and/or oil, much more effectively than the solvent (or a solvent and surfactant blend) can dissolve them. In water-in-oil (W/O) and oil-in-water (O/W) microemulsions with 10 and 90 wt% water, respectively, the normalized maximal solubilization efficiency α is ca. 20-fold larger than its solubility. The solubilization capacity of the system is mainly surfactant-concentration dependent. The lycopene resides at the interfaces of the W/O and O/W microemulsions and engenders significant structural changes in the organization of the microemulsion droplets. In the absence of lycopene, the droplets are spherical; when lycopene is added, compaction of the droplets and formation of threadlike droplets are observed. On further addition of lycopene, the bridging effect wanes and the droplets revert to a spherical shape. The enhanced solubilization demonstrated for lycopene opens up new options for formulators interested in making liquid and transparent products for cosmetic or pharmaceutical uses.

Key Words

Brij 96V jojoba oil lycopene microemulsion solubilization 

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Copyright information

© AOCS Press 2004

Authors and Affiliations

  1. 1.Casali Institute of Applied ChemistryThe Hebrew University of JerusalemIsrael
  2. 2.Department of ChemistryBen-Gurion University of the NegevBe’er-ShevaIsrael

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