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Effect of Conjugated Linoleic Acid on Cyprinus carpio var. Jian Regarding Growth, Immunity, and Disease Resistance to Aeromonas hydrophila

  • Original Article
  • Published:
Lipids

Abstract

The present study was performed to investigate the effect of dietary conjugated linoleic acid (CLA) on the growth performance, immune parameters and disease resistance to Aeromonas hydrophila of juvenile Jian carp. A total of 900 juvenile Jian carp (10.71 ± 0.02 g) were randomly allocated into six groups of each three replicates, feeding isonitrogenous (35% crude protein) and isolipidic (7.8% crude fat) diets containing graded amounts of CLA (0, 0.5, 0.8, 1.4, 1.7, and 2.0%) for 60 days. After a 60-day growth test, a challenge trial was conducted by intraperitoneal injection of Aeromonas hydrophila to determine the effect of CLA on disease resistance of juvenile Jian carp. The results showed that diets incorporated with a proportion of up to 2.0% CLA without effect on weight gain, feed intake, and feed conversion ratio, but improved immune parameters and disease resistance of juvenile Jian carp. The dietary CLA level of optimal disease resistance to Aeromonas hydrophila was estimated to be 1.7% in juvenile Jian carp using broken-line analysis.

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Abbreviations

CLA:

Conjugated linoleic acid

LD50 :

50% lethal dose

CFU:

Clonal formation unit

SD:

Standard deviation

FI:

Feed intake

WG:

Weight gain

FCR:

Feed conversion ratio

RBC:

Red blood cell count

WBC:

White blood cell count

SRF:

Survival rate during growth trail

SRV:

Survival rate after challenge

LA:

Lysozyme activity

TIBC:

Total iron-binding capacity

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Acknowledgments

The National Science Foundation of China (30771671, 30871926) financially supported this research. The authors wish to thank the personnel of these teams for their kind assistance.

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Authors and Affiliations

  1. Institute of Animal Nutrition, Sichuan Agricultural University, Yaan, 625014, Sichuan, China

    Jun Jiang, Ming-jiang Zhao, Feng Lin, Liu Yang & Xiao-qiu Zhou

  2. Aquaculture Department, Sichuan Agricultural University, Yaan, Sichuan, China

    Jun Jiang & Xiao-qiu Zhou

Authors
  1. Jun Jiang
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  2. Ming-jiang Zhao
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  3. Feng Lin
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  4. Liu Yang
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  5. Xiao-qiu Zhou
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Correspondence to Xiao-qiu Zhou.

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Jiang, J., Zhao, Mj., Lin, F. et al. Effect of Conjugated Linoleic Acid on Cyprinus carpio var. Jian Regarding Growth, Immunity, and Disease Resistance to Aeromonas hydrophila . Lipids 45, 531–536 (2010). https://doi.org/10.1007/s11745-010-3425-0

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  • DOI: https://doi.org/10.1007/s11745-010-3425-0

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