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Increasing homicide rates and linoleic acid consumption among five western countries, 1961–2000


Clinical intervention trials and animal studies indicate that increasing dietary intakes of long chain n−3 FA or reducing linoleic acid intake may reduce aggressive and violent behaviors. Here we examine if economic measures of greater n−6 consumption across time and countries correlate with greater risk of homicide. Linoleic acid available for human consumption was calculated from World Health Organization disappearance data for 12 major seed oils in the food supply for the years 1961 to 2000 in Argentina, Australia, Canada, the United Kingdom, and the United States (US). Homicide mortality rates, adjusted for age, were obtained from the central judicial authority of each country. Apparent linoleic acid intake from seed oil sources ranged from 0.29 en% (percentage of daily food energy) (Australia 1962) to 8.3 en% (US 1990s). Greater apparent consumption of linoleic acid correlated with higher rates of homicide mortality over a 20-fold range (0.51–10.2/100,000) across countries and time in an exponential growth regression model (r=0.94, F=567, P<0.00001). Within each country, correlations between greater linoleic acid disappearance and homicide mortality over time were significant in linear regression models. Randomized controlled trials are needed to determine if reducing high intakes of linoleic acid by seed oils with alternative compositions can reduce the risk of violent behaviors. These dietary interventions merit exploration as relatively cost-effective measures for reducing the pandemic of violence in Western societies, just as dietary interventions are reducing cardiovascular mortality. Low linoleate diets may prevent behavioral maladies that correctional institutions, social service programs, and mental health providers intend to treat.

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docosahexaenoic acid


percentage of daily food energy


eicosapentaenoic acid


World Health Organization


  1. Broadhurst, C., Cunnane, S., and Crawford, M. (1998) Rift Valley Lake Fish and Shellfish Provided Brain-Specific Nutrition for Early Homo, Br. J. Nutr. 79, 3–21.

    PubMed  CAS  Article  Google Scholar 

  2. Walter, R.C., Buffler, R.T., Bruggemann, J.H., Guillaume, M.M., Berhe, S.M., Negassi, B., Libsekal, Y., Cheng, H., Edwards, R.L., von Cosel, R., Neraudeau, D., and Gagnon, M. (2000) Early Human Occupation of the Red Sea Coast of Eritrea During the Last Interglacial Nature 405, 65–69.

    PubMed  CAS  Article  Google Scholar 

  3. Niu, S.L., Mitchell, D.C., Lim, S.Y., Wen, Z.M., Kim, H.Y., Salem, N., Jr., and Litman, B.J. (2004) Reduced G Protein-Coupled Signaling Efficiency in Retinal Rod Outer Segments in Response to n−3 Fatty Acid Deficiency, J. Biol. Chem. 279, 31098–31104.

    PubMed  CAS  Article  Google Scholar 

  4. Salem, N., Jr., and Niebylski, C.D. (1995) The Nervous System Has an Absolute Molecular Species Requirement for Proper Function, Mol. Membr. Biol. 12, 131–134.

    PubMed  CAS  Google Scholar 

  5. Gerrior, S., and Bente, L. (2002) Nutrient Content of the U.S. Food Supply, 1909–1999: A Summary Report, Home Economics Research Report. No 55, U.S. Department of Agriculture, Center for Nutrition Policy and Promotion, Washington, DC., Netlink: (accessed December 2004).

    Google Scholar 

  6. Rahm, J.J., and Holman, R.T. (1964) Effect of Linoleic Acid upon the Metabolism of Linolenic Acid, J. Nutr. 84, 15–19.

    PubMed  CAS  Google Scholar 

  7. Hibbeln, J.R., and Salem, N., Jr. (1995) Dietary Polyunsatured Fatty Acids and Depression: When Cholesterol Does Not Satisfy, Am. J. Clin. Nutr. 62, 1–9.

    PubMed  CAS  Google Scholar 

  8. Hibbeln, J.R. (2001) Seafood Consumption and Homicide Mortality, World Rev. Nutr. Diet 85, 41–46.

    Google Scholar 

  9. Iribarren, C., Markovitz, J.H., Jacobs, D.R., Schreiner, P.J., Daviglus, M., and Hibbeln, J.R. (2004) Dietary Intake of n−3, n−6 Fatty Acids and Fish: Relationship with Hostility in Young Adults—The CARDIA Study, Eur. J. Clin. Nutr. 58, 24–31.

    PubMed  CAS  Article  Google Scholar 

  10. Buydens-Branchey, L., Branchey, M., McMakin, D.L., and Hibbeln, J.R. (2003) Polyunsaturated Fatty Acid Status and Aggression in Cocaine Addicts, Drug Alcohol Depend. 71, 319–323.

    PubMed  CAS  Article  Google Scholar 

  11. Virkkunen, M.E., Horrobin, D.F., Jenkins, D.K., and Manku, M.S. (1987) Plasma Phospholipids, Essential Fatty Acids and Prostaglandins in Alcoholic, Habitually Violent and Impulsive Offenders, Biol. Psychiatry 22, 1087–1096.

    PubMed  CAS  Article  Google Scholar 

  12. Federal Bureau of Investigation. (2000) Homicide Trends in the United States. Uniform Crime Reports, 1950–99, Department of Justice, US Federal Government, Netlink: (accessed December 2004).

  13. Home Office. (2002) Criminal Statistics, National Statistics of the United Kingdom. (accessed September 2004)

  14. Statistics Canada. (2001) Homicide in Canada, 85-002-XPE Government of Canada, Netlink: (accessed December 2004).

  15. Ministerio de Justicia de la Nación. (2003) Registro Nacional de Reincidencia y Estadística Criminal, Government of Argentina, Buenos Aires.

    Google Scholar 

  16. Australian Institute of Criminology. (2002) Adapted from Causes of Death Australia, Catalogue No. 3303.0, Australian Bureau of Statistics, Netlink: abs@nsf/Lookup/C86E6B498E247877CA256889000CCDE0 (accessed December 2004).

  17. FAO/WHO. (2004) FAOSTAT Database, Food and Agricultural Organization of the United Nations, Sept 9, 2004, Netlink: (accessed September 2004).

  18. Krug, E.G., Powell, K.E., and Dahlberg, L.L. (1998) Firearm-Related Deaths in the United States and 35 Other High- and Upper-Middle-Income Countries, Int. J. Epidemiol. 27, 214–221.

    PubMed  CAS  Article  Google Scholar 

  19. Dandurand, Y. (1998) Firearms, Accidental Deaths, Suicide and Violent Crime: An Updated Review of the Literature with Special Reference to the Canadian Situation, WD1998-4e International Centre for Criminal Law Reform and Criminal Justice Policy, Netlink: (accessed December 2004).

  20. Australian Institute on Criminality. (2000) Australian Crime: Facts and Figures 2000. Homicide Involving Firearms as a Percentage of Total Homicide, 1915 to 1998, Australian Government, Netlink: /sec3.html (accessed December 2004).

  21. Smith, C., and Allen, J. (2004) Violent Crime in England and Wales, Home Office Online Report 18/04, Home Office Research, Development and Statistics Directorate Communication Development Unit, Netlink: pdfs04/rdsolr1804.pdf (accessed December 2004).

  22. Department of Justice. (2004) FBI Uniform Crime Reports Online, U.S. Federal Government, Netlink: http://bjsdata. (accessed December 2004).

  23. Hemenway, D., and Miller, M. (2000) Firearm Availability and Homicide Rates Across 26 High-Income Countries, J. Trauma 49, 985–988.

    PubMed  CAS  Google Scholar 

  24. Krug, E.G., Dahlberg, L., Mercy, J.C., Zwi, A.B., and Lozano, R. (2002) World Report on Violence and Health, World Health Organization, Netlink: prevention/violence/world_report/en (accessed December 2004).

  25. American Academy of Pediatrics. (2000) Joint Statement on the Impact of Entertainment Violence on Children: Congressional Public Health Summit, Dec. 6, Netlink: (accessed December 2004).

  26. Sanders, T.A. (2000) Polyunsaturated Fatty Acids in the Food Chain in Europe, Am. J. Clin. Nutr. 71, 176S-178S.

    PubMed  CAS  Google Scholar 

  27. Meyer, B.J., Mann, N.J., Lewis, J.L., Milligan, G.C., Sinclair, A.J., and Howe, P.R. (2003) Dietary Intakes and Food Sources of Omega-6 and Omega-3 Polyunsaturated Fatty Acids, Lipids 38, 391–398.

    PubMed  CAS  Google Scholar 

  28. Hibbeln, J.R. (2001) Seafood Consumption and Homicide Mortality: A Cross-National Ecological Analysis, World Rev. Nutr. Diet. 88, 41–46.

    PubMed  CAS  Article  Google Scholar 

  29. Zanarini, M.C., and Frankenburg, F.R. (2003) Omega-3 Fatty Acid Treatment of Women with Borderline Personality Disorder: A Double-Blind, Placebo-Controlled Pilot Study, Am. J. Psychiatry 160, 167–169.

    PubMed  Article  Google Scholar 

  30. Stevens, L., Zhang, W., Peck, L., Kuczek, T., Grevstad, N., Mahon, A., Zentall, S.S., Arnold, L.E., and Burgess, J.R. (2003) EFA Supplementation in Children with Inattention, Hyperactivity, and Other Disruptive Behaviors, Lipids 38, 1007–1021.

    PubMed  CAS  Article  Google Scholar 

  31. Hirayama, S., Hamazaki, T., and Terasawa, K. (2004) Effect of Docosahexaenoic Acid-Containing Food Administration on Symptoms of Attention-Deficit/Hyperactivity Disorder—A Placebo-Controlled Double-Blind Study, Eur. J. Clin. Nutr. 58, 467–473.

    PubMed  CAS  Article  Google Scholar 

  32. Hamazaki, T., Thienprasert, A., Kheovichai, K., Samuhaseneetoo, S., Nagasawa, T., and Watanabe, S. (2002) The Effect of Docosahexaenoic Acid on Aggression in Elderly Thai Subjects—A Placebo-Controlled Double-Blind Study, Nutr. Neurosci. 5, 37–41.

    CAS  Article  PubMed  Google Scholar 

  33. Hamazaki, T., Sawazaki, S., and Kobayashi, M. (1996) The Effect of Docosahexaenoic Acid on Aggression in Young Adults. A Double-Blind Study, J. Clin. Invest. 97, 1129–1134.

    PubMed  CAS  Google Scholar 

  34. Gesch, C.B., Hammond, S.M., Hampson, S.E., Eves, A., and Crowder, M.J. (2002) Influence of Supplementary Vitamins, Minerals and Essential Fatty Acids on the Antisocial Behaviour of Young Adult Prisoners: Randomised, Placebo-Controlled Trial, Br. J. Psychiatry 181, 22–28.

    PubMed  Article  Google Scholar 

  35. Raygada, M., Cho, E., and Hilakivi-Clarke, L. (1998) High Maternal Intake of Polyunsaturated Fatty Acids During Pregnancy in Mice Alters Offsprings' Aggressive Behavior, Immobility in the Swim Test, Locomotor Activity and Brain Protein Kinase C Activity, J. Nutr. 128, 2505–2511.

    PubMed  CAS  Google Scholar 

  36. Miachon, S., Augier, S., Jouvenet, M., Boucher, P., and Vallon, J.J. (2001) Nutritional Parameters Modify Muricidal Behavior of Male Wistar Rats: Preventive Effects Of Amino Acids and 4′ C1 Diazepam, Life Sci. 69, 2745–2757.

    PubMed  CAS  Article  Google Scholar 

  37. Augier, S., Penes, M.C., Debilly, G., and Miachon, A.S. (2003) Polyunsaturated Fatty Acids in the Blood of Spontaneously or Induced Muricidal Male Wistar Rats, Brain Res. Bull. 60, 161–165.

    PubMed  CAS  Article  Google Scholar 

  38. Stanley, B., Molcho, A., Stanley, M., Winchel, R., Gameroff, M.J., Parsons, B., and Mann, J.J. (2000) Association of Aggressive Behavior with Altered Serotonergic Function in Patients Who Are Not Suicidal, Am. J. Psychiatry 157, 609–614.

    PubMed  CAS  Article  Google Scholar 

  39. Highley, J.D. (2001) Individual Differences in Alcohol-Induced Aggression: A Nonhuman-Primate Model, Alcohol Res. Health 25, 12–19.

    PubMed  CAS  Google Scholar 

  40. Kodas, E., Galineau, L., Bodard, S., Vancassel, S., Guilloteau, D., Besnard, J.C., and Chalon, S. (2004) Serotoninergic Neurotransmission Is Affected by n−3 Polyunsaturated Fatty Acids in the Rat, J. Neurochem. 89, 695–702.

    PubMed  CAS  Article  Google Scholar 

  41. de la Presa Owens, S., and Innis, S.M. (1999) Docosahexaenoic and Arachidonic Acid Prevent a Decrease in Dopaminergic and Serotoninergic Neurotransmitters in Frontal Cortex Caused by a Linoleic and α-Linolenic Acid Deficient Diet in Formula-Fed Piglets, J. Nutr. 129, 2088–2093.

    PubMed  Google Scholar 

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Correspondence to Joseph R. Hibbeln.

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Hibbeln, J.R., Nieminen, L.R.G. & Lands, W.E.M. Increasing homicide rates and linoleic acid consumption among five western countries, 1961–2000. Lipids 39, 1207–1213 (2004).

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  • Linoleic Acid
  • Linoleate
  • Homicide Rate
  • Uniform Crime Report
  • Serotonergic Neurotransmission