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Synthesis and Antibacterial Activity of Novel Amido-Amine-Based Cationic Gemini Surfactants

  • Original Article
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Journal of Surfactants and Detergents

Abstract

A series of novel cationic gemini surfactants were synthesized from corresponding amido-amines in a single step reaction. The amido-amines were obtained from long chain carboxylic acids and 3-N,N-dimethylamino-1-propyl-amine with excellent isolated yield (up to 95 %). All the synthesized quaternary ammonium compounds (QACs) were further investigated for surface active properties. The critical micelle concentration (CMC) and the effectiveness of surface tension reduction were determined. The surface tension measurements of newly synthesized gemini surfactants showed good water solubility, and low CMC values, had great efficiency in lowering the surface tension and a strong adsorption at the air/water interface than the corresponding monomeric surfactants. Further, the antibacterial activity of the synthesized QACs against both Gram-positive and Gram-negative bacteria was also investigated.

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Acknowledgments

The author (AKG) is greatly thankful to the UGC (University Grant Commission, India) for providing a fellowship. The authors would also extend their special thanks to Mr. Sharad Gaikwad and Mr. Chetan Pawar, K. T. H. M. College, Nashik, Maharashtra, India for carrying out antibacterial activity analysis during this work.

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Authors and Affiliations

  1. Department of Chemical Engineering, Institute of Chemical Technology (Autonomous), Matunga, Mumbai, 400 019, India

    Anant K. Ghumare, Balu V. Pawar & Sunil S. Bhagwat

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  1. Anant K. Ghumare
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  2. Balu V. Pawar
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  3. Sunil S. Bhagwat
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Correspondence to Sunil S. Bhagwat.

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Ghumare, A.K., Pawar, B.V. & Bhagwat, S.S. Synthesis and Antibacterial Activity of Novel Amido-Amine-Based Cationic Gemini Surfactants. J Surfact Deterg 16, 85–93 (2013). https://doi.org/10.1007/s11743-012-1406-4

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  • DOI: https://doi.org/10.1007/s11743-012-1406-4

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