Abstract
To broaden the applications of magnetized water (MW) in medical science, the possible detoxicative effect of MW to anticancer drugs in vivo were studied. After being given ip with cyclophosphomide (CTX) 500 mg/kg, cisplatin (DDP) 40 mg/kg, harringtonine (HA) 20 mg/kg, mitomycin C (MMC) 8 mg/kg, lycobetaine (Lyc) 200 mg/kg, respectively, the mice were given MW ip 0.2 ml for 7 days. The average life span was calculated for each group. After being given subacutely lower doses of anticancer drugs (CTX 100 mg/kg, HA 3 mg/kg) ip 3 times, the mice were given MW ip 0.2 ml for 7 days and the blood white cells were counted as routine. It was shown that the mice in MW groups after ip anticancer drugs survived longer than those without MW. The effects of various anticancer drugs on life span were different. The white cell numbers of groups with MW were higher than that of the groups without MW. So it is possible that MW can remarkably extend the life span of mice and attenuate the leukopenia by mitigating the toxicity of anticancer drugs in vivo.
Similar content being viewed by others
References
Wang Y.T., Dai Z.Y., Liu Z.Y., et al., Effect of magnetized water on T lymphocyte in mice, Chin J. Phys. Med., 1987, 9(1):36–38 (in Chinese)
Wang Y. T., Pan X.P., Liu T., et al., A brief study of the effect of magnetized water for scavenging murine free radicals, 7th National Symposium on Magnetism, Loudi, Hunan, 1990:812–813 (in Chinese)
Zhao D.Y., et al., The influences of magnetized water on blood pressure and cardiarrhythm of hypercholesterol rats, Chin. J. Med. Phys., 1993, 10(1):30–33 (in Chinese)
Lu D.Y., Xu J., Chen Y.F., et al., Effect of harringtonine on lymphocyte rossette formation and serum sialic acid level in mice bearing tumors, Acta. Oncol. Sin., 1992, 2(4):7–9 (in Chinese)
Xiao P., Pan Y.Z., Tan H., et al., Experimental observations of magnetic liquid impact on neoplasm cells, Chin. J. Phys. Med., 1985, 7(3):159–163 (in Chinese)
Wang Y.T., Wang X.J., Dai Z.Y., et al., Effect of magnetized water on growth of S180 in mice, Chin. J. Phys. Med., 1989, 11(2): 87–90 (in Chinese)
Chang H.Y., Li G.Y., Pan Y.M., et al., Effect of magnetic field on S180 sarcomas in mice experimental observation, Chin. J. Phys. Med., 1985, 7(3):169–170 (in Chinese)
Author information
Authors and Affiliations
About this article
Cite this article
Lu, D., Shen, W., Cao, J. et al. Effect of magnetized water on the mice given high doses of antineoplastic drugs. J. of Shanghai Univ. 3, 81–83 (1999). https://doi.org/10.1007/s11741-999-0036-1
Received:
Issue Date:
DOI: https://doi.org/10.1007/s11741-999-0036-1