Skip to main content
Log in

Exploring IL-1 inhibition in chronic refractory idiopathic myocarditis: emerging insights and perspectives

  • IM - COMMENTARY
  • Published:
Internal and Emergency Medicine Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Data availability

Not applicable.

References

  1. Del Buono MG, Bonaventura A, Vecchie A, Moroni F, Golino M, Bressi E, De Ponti R, Dentali F et al (2023) Pathogenic pathways and therapeutic targets of inflammation in heart diseases: a focus on Interleukin-1. Eur J Clin Invest. https://doi.org/10.1111/eci.14110

    Article  PubMed  Google Scholar 

  2. Thurner L, Kessel C, Fadle N, Regitz E, Seidel F, Kindermann I, Lohse S, Kos I et al (2022) IL-1RA antibodies in myocarditis after SARS-CoV-2 vaccination. N Engl J Med 387:1524–1527. https://doi.org/10.1056/NEJMc2205667

    Article  PubMed  Google Scholar 

  3. Malandrino D, Bello F, Lopalco G, Cantarini L, Olivotto I, Emmi G, Prisco D (2023) Effectiveness and safety of IL1 inhibition with anakinra in chronic refractory idiopathic myocarditis. Intern Emerg Med. https://doi.org/10.1007/s11739-023-03514-2

    Article  PubMed  Google Scholar 

  4. Lazzerini PE, Abbate A, Boutjdir M, Capecchi PL (2023) Fir(e)ing the rhythm: inflammatory cytokines and cardiac arrhythmias. JACC Basic Transl Sci 8:728–750. https://doi.org/10.1016/j.jacbts.2022.12.004

    Article  PubMed  PubMed Central  Google Scholar 

  5. Thorolfsdottir RB, Jonsdottir AB, Sveinbjornsson G, Aegisdottir HM, Oddsson A, Stefansson OA, Halldorsson GH, Saevarsdottir S et al (2023) Variants at the Interleukin 1 gene locus and pericarditis. JAMA Cardiol. https://doi.org/10.1001/jamacardio.2023.4820

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Maddalena Alessandra Wu.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Wu, M.A., Bizzi, E. & Brucato, A. Exploring IL-1 inhibition in chronic refractory idiopathic myocarditis: emerging insights and perspectives. Intern Emerg Med 19, 273–274 (2024). https://doi.org/10.1007/s11739-024-03552-4

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11739-024-03552-4

Keywords

Navigation