Skip to main content

Advertisement

Log in

Utility of pulmonary echography with a handheld ultrasound device in patients with acute coronary syndrome

  • EM - ORIGINAL
  • Published:
Internal and Emergency Medicine Aims and scope Submit manuscript

Abstract

The objectives of this study are to establish the usefulness of lung ultrasound with a handheld device to predict the risk of developing heart failure with the need for mechanical ventilation (MV) in acute coronary syndrome (ACS). This is a prospective study of consecutive patients admitted because of ACS-type myocardial infarction, without data of HF at admission in a tertiary hospital, between February 2017 and February 2018. Lung ultrasounds were performed with a handheld cardiologic device in the first 24 h, and defined as echo-positive (PE+) when exams revealed 3 or more B-lines in 2 or more bilateral quadrants. We related this finding to the need for MV during admission. We included 119 patients (65.1 ± 12.8 year; 75.6% male, 24.4% female; 87.4% in Killip class I, 12.6% in Killip class II). Pulmonary echography was positive (PE+) in 21 patients (17.6%). The sensitivity of PE+ to predict MV was 93.3%, the specificity 93.3%, and the area under the curve 0.93. In Cox regression analysis adjusted by CRUSADE score and Killip class, PE+ patients had a hazard ratio of 64.55 (CI 7.87; 529.25, p < 0.001) of needing MV. PE+ was associated with more frequent use of inotropes and mortality. Pulmonary ultrasonography with a handheld echocardiograph was predictive of severe heart failure and the need for mechanical ventilation in ACS with high specificity and sensitivity.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Mortality and global health estimates [Internet]. [cited 2022 May 11]. Available from: https://www.who.int/data/gho/data/themes/mortality-and-global-health-estimates

  2. Rodríguez-Padial L, Bertomeu V, Elola FJ, Anguita M, Fernández Lozano I, Silva L et al (2016) Quality improvement strategy of the Spanish society of cardiology: the RECALCAR registry. J Am Coll Cardiol 68(10):1140–1142

    Article  Google Scholar 

  3. Arrigo M, Gayat E, Parenica J, Ishihara S, Zhang J, Choi DJ et al (2017) Precipitating factors and 90-day outcome of acute heart failure: a report from the intercontinental GREAT registry. Eur J Heart Fail 19(2):201–208

    Article  Google Scholar 

  4. de Carvalho LP, Gao F, Chen Q, Sim LL, Koh TH, Foo D et al (2015) Long-term prognosis and risk heterogeneity of heart failure complicating acute myocardial infarction. Am J Cardiol 115(7):872–878

    Article  Google Scholar 

  5. Harjola V, Mullens W, Banaszewski M, Bauersachs J, Brunner-La Rocca H, Chioncel O et al (2017) Organ dysfunction, injury and failure in acute heart failure: from pathophysiology to diagnosis and management. A review on behalf of the acute heart failure committee of the heart failure association (HFA) of the European society of cardiology (ESC). Eur J Heart Fail 19:821–836

    Article  Google Scholar 

  6. Platz E, Campbell RT, Claggett B, Lewis EF, Groarke JD, Docherty KF et al (2019) Lung ultrasound in acute heart failure: prevalence of pulmonary congestion and short- and long-term outcomes. JACC Heart Fail 7(10):849–858

    Article  Google Scholar 

  7. Picano E, Scali MC (2017) The lung water cascade in heart failure. Echocardiography 34(10):1503–1507

    Article  Google Scholar 

  8. Picano E, Pellikka PA (2016) Ultrasound of extravascular lung water: a new standard for pulmonary congestion. Eur Heart J 37(27):2097–2104

    Article  Google Scholar 

  9. Jambrik Z, Monti S, Coppola V, Agricola E, Mottola G, Miniati M et al (2004) Usefulness of ultrasound lung comets as a nonradiologic sign of extravascular lung water. Am J Cardiol 93(10):1265–1270

    Article  Google Scholar 

  10. Leidi F, Casella F, Cogliati C (2016) Bedside lung ultrasound in the evaluation of acute decompensated heart failure. Intern Emerg Med 11(4):597–601

    Article  Google Scholar 

  11. Colmenero M, García-Delgado M, Navarrete I, López-Milena G (2010) Utility of the lung ultrasound in the intensive medicine unit. Med Intensiva 34(9):620–628

    Article  CAS  Google Scholar 

  12. Bianco F, Bucciarelli V, Ricci F, De Caterina R, Gallina S (2017) Lung ultrasonography: a practical guide for cardiologists. J Cardiovasc Med 18(7):501–509

    Article  Google Scholar 

  13. Soldati G, Demi M (2017) The use of lung ultrasound images for the differential diagnosis of pulmonary and cardiac interstitial pathology. J Ultrasound 20(2):91–96

    Article  Google Scholar 

  14. Lichtenstein DA (2015) BLUE-protocol and FALLS-protocol: two applications of lung ultrasound in the critically ill. Chest 147(6):1659–1670

    Article  Google Scholar 

  15. Haaksma ME, Smit JM, Heldeweg MLA, Pisani L, Elbers P, Tuinman PR (2020) Lung ultrasound and B-lines: B careful! Intensive Care Med 46(3):544–545. https://doi.org/10.1007/s00134-019-05911-8

    Article  CAS  Google Scholar 

  16. Suarez J, Niyyar VD (2021) Lung ultrasound: a “biomarker” for fluid overload? Adv Chronic Kidney Dis 28(3):200–207

    Article  Google Scholar 

  17. Thygesen K, Alpert JS, Jaffe AS, Chaitman BR, Bax JJ, Morrow DA et al (2018) Fourth universal definition of myocardial infarction (2018). Circulation 138(20):e618–e651

    Article  Google Scholar 

  18. Volpicelli G, Mussa A, Garofalo G, Cardinale L, Casoli G, Perotto F et al (2006) Bedside lung ultrasound in the assessment of alveolar-interstitial syndrome. Am J Emerg Med 24(6):689–696

    Article  Google Scholar 

  19. Kaul P, Ezekowitz JA, Armstrong PW, Leung BK, Savu A, Welsh RC et al (2013) Incidence of heart failure and mortality after acute coronary syndromes. Am Heart J 165(3):379-385.e2

    Article  Google Scholar 

  20. Stelzle D, Shah ASV, Anand A, Strachan FE, Chapman AR, Denvir MA et al (2018) High-sensitivity cardiac troponin I and risk of heart failure in patients with suspected acute coronary syndrome: a cohort study. Eur Heart J Qual Care Clin Outcomes 4(1):36–42

    Article  Google Scholar 

  21. Jenča D, Melenovský V, Stehlik J, Staněk V, Kettner J, Kautzner J et al (2021) Heart failure after myocardial infarction: incidence and predictors. ESC Heart Fail 8(1):222–237

    Article  Google Scholar 

  22. Chan Pin Yin D, Azzahhafi J, James S (2020) Risk assessment using risk scores in patients with acute coronary syndrome. J Clin Med 9(9):1–16

    Article  Google Scholar 

  23. Cordero A, Rodriguez-Manero M, García-Acuña JM, López-Palop R, Cid B, Carrillo P et al (2017) Additive value of the CRUSADE score to the GRACE score for mortality risk prediction in patients with acute coronary syndromes. Int J Cardiol 15(245):1–5

    Article  Google Scholar 

  24. Cardinale L, Priola AM, Moretti F, Volpicelli G (2014) Effectiveness of chest radiography, lung ultrasound and thoracic computed tomography in the diagnosis of congestive heart failure. World J Radiol 6(6):230–237

    Article  Google Scholar 

  25. Kimura BJ, Nayak KR (2020) “Asymptomatic” flash pulmonary edema by point-of-care ultrasound: a novel bedside finding of transient global ischemia. JACC Case Rep 2(10):1545–1549

    Article  Google Scholar 

  26. Bedetti G, Gargani L, Sicari R, Gianfaldoni ML, Molinaro S, Picano E (2010) Comparison of prognostic value of echocardiacgraphic risk score with the thrombolysis in myocardial infarction (TIMI) and global registry in acute coronary events (GRACE) risk scores in acute coronary syndrome. Am J Cardiol 106(12):1709–1716

    Article  Google Scholar 

  27. Killip T, Kimball JT (1967) Treatment of myocardial infarction in a coronary care unit. A two year experience with 250 patients. Am J Cardiol 20(4):457–464

    Article  Google Scholar 

  28. Mayo PH, Copetti R, Feller-Kopman D, Mathis G, Maury E, Mongodi S et al (2019) Thoracic ultrasonography: a narrative review. Intensive Care Med 45(9):1200–1211

    Article  CAS  Google Scholar 

  29. Johannessen Ø, Myhre PL, Omland T (2021) Assessing congestion in acute heart failure using cardiac and lung ultrasound - a review. Expert Rev Cardiovasc Ther 19(2):165–176

    Article  CAS  Google Scholar 

  30. Miglioranza MH et al (2017) Pulmonary congestion evaluated by lung ultrasound predicts decompensation in heart failure outpatients. Int J Cardiol 240:271–278

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Juan Carlos Garcia-Rubira.

Ethics declarations

Conflict of interest

The author(s) declare that they have no conflict of interest.

Ethical approval

This work was performed in accordance with the ethical standards of the 1964 Helsinki Declaration and was approved by the Ethics Commity of the Hospital.

Informed consent

Informed consent of the patients was required to be included.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

This work has been previously published as an abstract in ESC Congress 2020-The Digital Experience 29 August–1 September.

Supplementary Information

Below is the link to the electronic supplementary material.

Supplementary file1 (TIF 2415 KB)

Supplementary file2 (DOCX 463 KB)

Rights and permissions

Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Cristo Ropero, M.J., Rivera Rabanal, F.J., Seoane García, T. et al. Utility of pulmonary echography with a handheld ultrasound device in patients with acute coronary syndrome. Intern Emerg Med 18, 249–255 (2023). https://doi.org/10.1007/s11739-022-03113-7

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11739-022-03113-7

Keywords

Navigation