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Table 3 Descriptive Statistics for sICAM-1, HDL and FEV1 at Baseline (day 1), Day 90 and Day 180 in the Day 180 CEVal-compliant per-protocol population

From: Changes in biomarkers after 180 days of tobacco heating product use: a randomised trial

Biomarker (units) Groupa Nb Day 1 Day 90 Day 180
sICAM-1c (ng/mL) A 58–59 474.3 (444.4, 504.2) 491.0 (454.9, 527.1) 501.8 (463.6, 540.0)
B 94–97 464.4 (437.6, 491.1) 428.0 (409.1, 447.0) 433.2 (410.3, 456.1)
HDLd (mmol/L) A 58–59 1.39 (1.29, 1.49) 1.39 (1.28, 1.49) 1.37 (1.26, 1.49)
B 94–97 1.41 (1.34, 1.48) 1.49 (1.41, 1.57) 1.48 (1.40, 1.56)
FEV1%prede A 55–58 91.5 (88.5, 94.5) 90.1 (87.0, 93.1) 88.1 (85.1, 91.0)
B 89–93 91.9 (89.7, 94.2) 92.8 (90.5, 95.1) 93.0 (90.8, 95.1)
  1. Data are means with lower and upper 95% confidence intervals in parentheses
  2. aGroup A continue to smoke combustible cigarettes, Group B, switch to THP
  3. bN, number of participants (for details of participant composition refer to Supplementary Table 1)
  4. csICAM-1 soluble intercellular adhesion molecule-1
  5. dHDL high-density lipoprotein
  6. eFEV1%pred forced expiratory volume in 1 s percentage of predicted
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