A 29-year-old woman with persistent thrombocytopenia

This is a preview of subscription content, log in to check access.

Fig. 1

References

  1. 1.

    Cines DB, Bussel JB, Liebman HA, Luning Prak ET (2009) The ITP syndrome: pathogenic and clinical diversity. Blood 113(26):6511–6521

    CAS  Article  Google Scholar 

  2. 2.

    Rodeghiero F, Stasi R, Gernsheimer T et al (2009) Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura of adults and children: report from an international working group. Blood 113(11):2386–2393

    CAS  Article  Google Scholar 

  3. 3.

    McMillan R, Durette C (2004) Long-term outcomes in adults with chronic ITP after splenectomy failure. Blood 104(4):956–960

    CAS  Article  Google Scholar 

  4. 4.

    Broudy VC, Lin NL (2004) AMG531 stimulates megakaryopoiesis in vitro by binding to Mpl. Cytokine 25:52–60

    CAS  Article  Google Scholar 

  5. 5.

    Kuter DJ, Bussel JB, Lyons RM et al (2008) Efficacy of romiplostim in patients with chronic immune thrombocytopenic purpura: a double-blind randomised controlled trial. Lancet 371:395–403

    CAS  Article  Google Scholar 

  6. 6.

    Bussel JB, Cheng G, Saleh MN et al (2007) Eltrombopag for the treatment of chronic idiopathic thrombocytopenic purpura. N Engl J Med 357:2237–2247

    CAS  Article  Google Scholar 

  7. 7.

    Cooper N (2017) State of the art—how I manage immune thrombocytopenia. Br J Haematol 177:39–54

    Article  Google Scholar 

  8. 8.

    Boruchov DM, Gururangan S, Driscoll MC, Bussel JB (2007) Multiagent induction and maintenance therapy for patients with refractory immune thrombocytopenic purpura (ITP). Blood 110:3526–3531

    CAS  Article  Google Scholar 

  9. 9.

    Mahévas M, Gerfaud-Valentin M, Moulis G, Terriou L, Audia S, Guenin S, Le Guenno G, Salles G, Lambotte O, Limal N, Viallard JF, Cheze S, Tomowiak C, Royer B, Neel A, Debouverie O, Hot A, Durieu I, Perlat A, Cliquennois M, Deteix C, Michel M, Godeau B (2016) Characteristics, outcome, and response to therapy of multirefractory chronic immune thrombocytopenia. Blood 128(12):1625–1630

    Article  Google Scholar 

  10. 10.

    Tauchi T, Suzuki A, Fujimura T, Iwabuchi H, Ohyashiki JH, Ohyashiki K et al (1989) Refractory idiopathic thrombocytopenic purpura which responded to protein A column. Rinsho Ketsueki 30(8):1289–1293

    CAS  PubMed  Google Scholar 

  11. 11.

    Fabris F, Luzzatto G, Ramon R, Randi ML, De Silvestro G, Girolami A (2000) Treatment of refractory ITP with extracorporeal immunoadsorption over a protein-A sepharose column: a report of two cases. Haematologica 85(8):888–890

    Google Scholar 

  12. 12.

    Kurtoğlu E, Karakuş V, Deveci B (2013) Refractory idiopathic thrombocytopenic purpura treated with immunoadsorption using tryptophan column. Transfus Apheres Sci 48:311–312

    Article  Google Scholar 

  13. 13.

    Kotb R, Pinganaud C, Trichet C et al (2005) Efficacy of mycophenolate mofetil in adult refractory autoimmune cytopenias: a single-center preliminary study. Eur J Haematol 75(1):60–64

    CAS  Article  Google Scholar 

  14. 14.

    Taylor A, Neave L, Solanki S, Westwood JP, Terrinonive I, McGuckin S, Kothari J, Cooper N, Stasi R, Scully M (2015) Mycophenolate mofetil therapy for severe immune thrombocytopenia. Br J Haematol 171:625–630

    CAS  Article  Google Scholar 

Download references

Author information

Affiliations

Authors

Corresponding author

Correspondence to Irene Di Pasquale.

Ethics declarations

Conflicts of interest

The authors have no conflicts of interest to disclose.

Statement of human and animal rights

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Di Pasquale, I., Bertomoro, A., Vianello, F. et al. A 29-year-old woman with persistent thrombocytopenia. Intern Emerg Med 14, 1317–1320 (2019). https://doi.org/10.1007/s11739-019-02030-6

Download citation