Internal and Emergency Medicine

, Volume 5, Issue 2, pp 169–171 | Cite as

Acquired haemophilia A: a case report

  • Daniela Colomba
  • Domenico Di RaimondoEmail author
  • Luciana Marino
  • Rita Marrone
  • Giuseppe Licata
CE - Letter to the Editor

We report a case of an 84-year-old woman, who presented with spontaneous haematomas, and gastrointestinal and urological bleeding. The past medical history included arterial hypertension and a diagnosis of dementia, no history of pre-existing autoimmune diseases or inherited haemorrhagic disorders. One month before the admission to our division, she was brought to the emergency department (ED) for epistaxis, macrohaematuria and melena, and because of severe anaemia (Hb 7 g/dl) she required blood transfusions.

One month later she was admitted to the hospital for the appearance of skin haematomas extending to the thorax, abdomen and legs associated with severe microcytic, hypochromic anaemia. She needed further blood transfusions (2 red cell units, RCU) to improve haemoglobin levels.

On physical examination, she was noted to be in acute distress, but appear neither tachypneic nor cyanotic. The vital signs were: temperature 36.8°C, blood pressure 105/60 mm Hg, heart rate 98 beats per...


Factor Viii Recombinant Factor VIIa Sjogren Syndrome Factor Viii Level Factor Viii Inhibitor 
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Conflict of interest statement

The authors declare that they have no conflict of interest related to the publication of this manuscript.


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Copyright information

© SIMI 2009

Authors and Affiliations

  • Daniela Colomba
    • 1
  • Domenico Di Raimondo
    • 1
    Email author
  • Luciana Marino
    • 1
  • Rita Marrone
    • 1
  • Giuseppe Licata
    • 1
  1. 1.Dipartimento Biomedico di Medicina Interna e Specialistica AOU Policlinico “P. Giaccone”Università degli Studi di PalermoPalermoItaly

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