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Clinical study of treating somatoform pain disorder with the combination of electroacupuncture and duloxetine

电针联合度洛西汀治疗躯体形式疼痛障碍临床观察

  • Clinical Study
  • Published:
Journal of Acupuncture and Tuina Science Aims and scope Submit manuscript

Abstract

Objective

To observe the clinical efficacy of treating somatoform pain disorder (SPD) with electroacupuncture (EA) at the Governor and Conception Vessel points plus duloxetine.

Methods

Eighty-two SPD patients were randomly allocated to an observation group and a control group, with 41 cases in each group. The control group was intervened by oral administration of duloxetine hydrochloride enteric capsules at a dose of 60 mg per time once a day; based on the medication, the observation group received additional EA treatment by selecting points from the Governor and Conception Vessels. Clinical efficacy was evaluated after 8 weeks of treatments; changes in the scores of the short-form McGill pain questionnaire (SF-MPQ), self-report symptom inventory, symptom check list-90 (SCL-90), Pittsburgh sleep quality index (PSQI), and generic quality of life inventory-74 (GQOLI-74) were also compared.

Results

After the intervention, the observation group surpassed the control group in comparing the total effective rate (P<0.05). The SF-MPQ score, SCL-90 somatization score, and PSQI score dropped notably in both groups after treatment, and the intra-group differences were statistically significant (P<0.05); the three scores were significantly lower in the observation group than in the control group (P<0.05). The GQOLI-74 score got an increase in each dimension in both groups after treatment, and the intra-group differences were also statistically significant (P<0.05); the GQOLI-74 dimension scores were all significantly higher in the observation group than in the control group (P<0.05).

Conclusion

For patients with SPD, combining EA at the Governor and Conception Vessel points and duloxetine hydrochloride enteric capsules can markedly improve their clinical symptoms and quality of life.

摘要

目的

观察电针督任脉穴位联合度洛西汀治疗躯体形式疼痛障碍的临床疗效。

方法

将82例躯体形式疼痛障碍患者随机分为观察组和对照组, 每组41例。对照组给予口服盐酸度洛西汀肠溶胶囊, 每次60 mg, 每日1次; 观察组在对照组用药基础上加用电针督任脉穴位治疗。两组均治疗8周后进行临床疗效评价, 并比较简化McGill 疼痛问卷(SF-MPQ)、症状自评量表(SCL-90)、匹兹堡睡眠质量指数(PSQI)及生活质量综合评定问卷(GQOLI-74)评分的变化情况。

结果

治疗后, 观察组总有效率高于对照组(P<0.05)。两组SF-MPQ评分、SCL-90中躯体化评分及PSQI评分均较本组治疗前显著下降, 组内差异有统计学意义(P<0.05), 且观察组三项评分均显著低于对照组(P<0.05)。两组患者GQOLI-74各维度评分均较本组治疗前显著升高, 组内差异均有统计学意义(P<0.05), 且观察组各维度评分均显著高于对照组(P<0.05)。

结论

电针督任脉穴位联合盐酸度洛西汀肠溶胶囊可以明显改善躯体形式疼痛障碍患者临床症状, 提高其生活质量。

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Acknowledgments

This work was supported by the Traditional Chinese Medicine Program of Hebei Provincial Administration of Traditional Chinese Medicine (河北省中医药管理局中医 药类科研计划课题, No. 2020262).

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Authors and Affiliations

  1. Tangshan Fifth Hospital, Hebei Province, Tangshan, 063000, China

    Yongsheng Dong  (董永生), Shuhong Sun  (孙淑红), Shuang Xu  (徐爽), Dongbo Yu  (于东波) & Wei Li  (李伟)

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  1. Yongsheng Dong  (董永生)
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  2. Shuhong Sun  (孙淑红)
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  3. Shuang Xu  (徐爽)
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  4. Dongbo Yu  (于东波)
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  5. Wei Li  (李伟)
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Correspondence to Shuhong Sun  (孙淑红).

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The authors declare that there is no potential conflict of interest in this article.

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Informed consent was obtained from all individual participants.

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Dong, Y., Sun, S., Xu, S. et al. Clinical study of treating somatoform pain disorder with the combination of electroacupuncture and duloxetine. J. Acupunct. Tuina. Sci. 21, 210–216 (2023). https://doi.org/10.1007/s11726-023-1378-0

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  • DOI: https://doi.org/10.1007/s11726-023-1378-0

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