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Effects of the combination of acupuncture and medication on orthostatic hypotension after incomplete cervical spinal cord injury

针药并用对颈髓不完全损伤后体位性低血压的影响

  • Clinical Study
  • Published:
Journal of Acupuncture and Tuina Science Aims and scope Submit manuscript

Abstract

Objective

To observe the effect of the combination of acupuncture and medication on orthostatic hypotension after incomplete cervical spinal cord injury.

Methods

Ninety-two patients with orthostatic hypotension after incomplete cervical spinal cord injury were divided into two groups according to the random number table method, with 46 cases in each group. The control group was treated with oral midodrine hydrochloride on the basis of conventional treatment, and the observation group was treated with acupuncture in addition to the intervention used in the control group. Both groups were treated for 4 weeks. The changes in supine and orthostatic blood pressures, motor and sensory scores, quadriplegic function index score, clinical efficacy, and safety evaluation were observed.

Results

During the treatment, 2 cases dropped out in the observation group, and 3 cases dropped out in the control group. After 4 weeks of treatment, the clinical efficacy of the observation group was better than that of the control group (P<0.05). After treatment, the supine systolic blood pressure and diastolic blood pressure in the two groups had no significant changes (P>0.05), while the orthostatic systolic blood pressure and diastolic blood pressure, the motor and sensory scores, and the quadriplegic function index score were significantly higher than those before treatment (P<0.05), and the scores in the observation group were higher than those in the control group (P<0.05). Adverse reactions were mild in both groups.

Conclusion

The combination of acupuncture and medication can significantly improve the orthostatic blood pressure, motor and sensory function and daily living ability of patients with orthostatic hypotension after incomplete cervical spinal cord injury, and it is safe and reliable.

摘要

目的

观察针药并用对颈髓不完全损伤后体位性低血压的影响。

方法

将92例颈髓不完全损伤后体位性低血 压患者根据随机数字表法分为两组, 每组46例。对照组在常规处理基础上采用口服盐酸米多君治疗, 观察组在对照组 干预基础上加用针刺治疗, 两组均治疗4周。观察两组治疗前后平卧位、直立位血压变化, 运动及感觉评分, 四肢瘫 功能指数评分以及临床疗效和安全性评价。

结果

治疗过程中观察组脱落2例, 对照组脱落3例。治疗4周后, 观察组 的临床疗效优于对照组(P<0.05)。治疗后, 两组患者平卧位的收缩压与舒张压未见明显变化(P>0.05), 而直立位的收缩 压和舒张压, 运动及感觉评分, 以及四肢瘫功能指数评分均显著高于本组治疗前(P<0.05), 观察组各项评分均高于对 照组(P<0.05)。两组的不良反应均轻微。

结论

针药并用可以明显提高颈髓不完全损伤后体位性低血压患者的直立位 血压, 运动及感觉功能和日常生活能力, 并且安全可靠。

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Acknowledgments

This work was supported by the 345 Talent Project of Shengjing Hospital of China Medical University (中国医科 大学附属盛京医院 345 优才工程).

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Authors and Affiliations

  1. Huludao Central Hospital, Liaoning Province, Huludao, 125001, China

    Jiye Liu  (刘继业) & Hong Meng  (孟红)

  2. China Medical University, Shenyang, 110122, China

    Jiye Liu  (刘继业)

  3. Shengjing Hospital of China Medical University, Shenyang, 110004, China

    Jiahe Wang  (王佳贺)

Authors
  1. Jiye Liu  (刘继业)
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  2. Hong Meng  (孟红)
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  3. Jiahe Wang  (王佳贺)
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Corresponding author

Correspondence to Jiahe Wang  (王佳贺).

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Conflict of Interest

The authors declare that there is no potential conflict of interest in this article.

Statement of Informed Consent

Informed consent was obtained from the families of each participant.

First Author: LIU Jiye, doctor degree candidate, attending physician

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Liu, J., Meng, H. & Wang, J. Effects of the combination of acupuncture and medication on orthostatic hypotension after incomplete cervical spinal cord injury. J. Acupunct. Tuina. Sci. 21, 59–65 (2023). https://doi.org/10.1007/s11726-023-1359-3

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  • DOI: https://doi.org/10.1007/s11726-023-1359-3

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