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Adjunctive effects of acupressure therapy on pain and quality of life in patients with knee osteoarthritis: an interventional study

指压疗法对膝骨关节炎患者疼痛和生活质量的辅助作用: 一项介入性研究

  • Clinical Study
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Abstract

Objective

To investigate the effect of acupressure therapy as an adjunctive therapy to pharmacological treatment on pain and health-related quality of life (QOL) among knee osteoarthritis (KOA) patients.

Methods

One hundred KOA patients were recruited from the orthopedic out-patient clinic of the institute. The patients were allocated randomly (flipping-coin simple randomization method) into an intervention group (n=50) and a control group (n=50). Patients in the intervention group received acupressure therapy along with pharmacological treatment. Patients in the control group did not receive acupressure therapy but continued their pharmacological treatment. Changes in pain (visual analog scale, VAS) and QOL (short-form 36-item health survey, SF-36) scores at baseline (A0), during training session (A1), follow-up at the 3rd month after training (A2) and follow-up at the 6th month after training session (A3) were collected and examined. Multiple regression analysis was used to check the relationship between pain and SF-36 domains.

Results

The VAS score of participants in the intervention group decreased at A3 (P=0.001). Scores of physical functioning (PF), role limitations due to emotional problems (RE) and mental health (MH) of SF-36 in the intervention group improved more as compared with the control group. Patients in the intervention group with improvement in VAS (pain) score showed greater changes in mean scores of all domains of SF-36 from baseline (all P<0.05). Except bodily pain (BP), the other domains of SF-36 were negatively correlated with pain score.

Conclusion

Acupressure therapy with pharmacological treatment can improve health-related QOL and pain among KOA patients.

摘要

目的

研究穴位指压疗法作为药物治疗的辅助手段对膝骨关节炎(KOA)患者疼痛和健康相关生活质量的影响.

方法

从本研究所骨科门诊纳入100名KOA患者. 将患者随机(掷币简单随机法)分为干预组(n=50)和对照组(n=50). 干 预组患者在药物治疗的同时接受穴位指压. 对照组患者仅接受药物治疗, 不予以穴位指压. 观察并记录治疗前基线 (A0), 治疗期间(A1), 治疗后第3个月随访(A2)和治疗后第6个月随访(A3)时疼痛[视觉模拟量表(VAS)]和生活质量[简明健康测量量表(SF-36)]评分. 运用多元回归分析法分析疼痛和SF-36各项之间的关系.

结果

干预组患者VAS评分第6个月随访时显著降低(P=0.001). 干预组SF-36中躯体功能(PF)、 情绪(RE)及心理健康(MH)评分较对照组改善更加显著. 干预组VAS(疼痛)评分改善的患者SF-36各项平均分较基线水平均有更显著变化(均P<0.05). 除躯体疼痛(BP)一项外, SF-36其他项评分均与疼痛评分呈负相关.

结论

穴位指压联合药物疗法可改善KOA患者的健康相关生活质量及疼痛.

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Authors and Affiliations

  1. Department of Pharmacology, Sawai Man Singh Medical College and Hospital, Jaipur, Rajasthan, 302004, India

    Meenu Rani, Lokendra Sharma & Uma Advani

  2. Department of Orthopedics, Sawai Man Singh Medical College and Hospital, Jaipur, Rajasthan, 302004, India

    Arun Sharma

Authors
  1. Meenu Rani
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  2. Lokendra Sharma
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Contributions

Meenu Rani: writing original draft, formal analysis, data curation; Lokendra Sharma: methodology, investigation, supervision; Uma Advani: data curation, review and editing, resources; Arun Sharma: resources, supervision.

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Correspondence to Meenu Rani.

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The authors certify that they have no affiliations with or involvement in any organization or entity with any financial or non-financial interest in the subject matter or materials discussed in this manuscript.

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Statement of Informed Consent

Informed consent was obtained from all individual participants in this study.

Author: Meenu Rani, Ph.D., scholar pharmacology.

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Rani, M., Sharma, L., Advani, U. et al. Adjunctive effects of acupressure therapy on pain and quality of life in patients with knee osteoarthritis: an interventional study. J. Acupunct. Tuina. Sci. 19, 300–306 (2021). https://doi.org/10.1007/s11726-021-1252-x

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  • DOI: https://doi.org/10.1007/s11726-021-1252-x

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