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Therapeutic efficacy observation of acupuncture plus medicine for laryngopharyngeal reflux due to liver-qi stagnation and spleen deficiency

针刺配合药物治疗肝郁脾虚型反流性咽喉炎的疗效观察

  • Clinical Study
  • Published:
Journal of Acupuncture and Tuina Science Aims and scope Submit manuscript

Abstract

Objective

To observe the clinical efficacy of acupuncture plus medicine in treating laryngopharyngeal reflux due to liverqi stagnation and spleen deficiency.

Methods

A total of 70 patients were divided into a control group and an observation group by the random number table method, with 35 cases in each group. Both groups were treated with conventional medications, and the observation group was treated with additional acupuncture therapy. The reflux symptom index (RSI) and reflux finding score (RFS) were evaluated. Esophageal motility indicators such as lower esophageal sphincter pressure (LESP) and upper esophageal sphincter pressure (UESP), and salivary pepsin level were measured. The clinical efficacy was also compared.

Results

The total effective rate of the observation group was higher than that of the control group (P<0.05). After treatment, the RSI and RFS scores in both groups decreased significantly (all P<0.05), and the RSI and RFS scores in the observation group were significantly lower than those in the control group (both P<0.05). There were no significant changes in the LESP and UESP in the control group (both P>0.05), while LESP and UESP in the observation group increased significantly (both P<0.05), and higher than those in the control group (both P<0.05). The salivary pepsin levels in both groups decreased (both P<0.05), and the salivary pepsin level in the observation group was significantly lower than that in the control group (P<0.05).

Conclusion

Acupuncture plus medicine can improve symptoms and signs in patients with laryngopharyngeal reflux due to liver-qi stagnation and spleen deficiency, and regulate esophageal motility and salivary pepsin level. Its efficacy is more significant compared with medicine alone.

【摘要】

目的: 观察针刺配合药物治疗肝郁脾虚型反流性咽喉炎的临床疗效。方法: 将70例患者按随机数字表法分为对照组和观察组, 每组35例。两组均接受常规药物治疗, 观察组另外加用针刺治疗。评定反流症状指数(RSI)、反流体征评分(RFS), 测定食管下括约肌压力(LESP)、食管上括约肌压力(UESP)等食管动力指标及唾液胃蛋白酶水平, 比较两组临床疗效。结果: 观察组有效率高于对照组(P<0.05); 治疗后, 两组RSI及RFS评分均显著降低(均P<0.05), 观察组RSI及RFS评分均显著低于对照组(均P<0.05); 对照组LESP及UESP无显著变化(均P>0.05), 观察组LESP及UESP显著增高(均P<0.05), 且高于对照组(均P<0.05); 两组唾液胃蛋白酶水平均降低(均P<0.05), 观察组唾液胃蛋白酶水平显著低于对照组(P<0.05)。结论: 针刺配合药物治疗肝郁脾虚型反流性咽喉炎可改善患者症状及体征, 调节食管动力及唾液胃蛋白酶水平, 其疗效优于单独药物治疗。

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Acknowledgments

This work was supported by Project of Hunan Province Administration of Traditional Chinese Medicine (湖南省中医药科研计划项目, No. 2019138).

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Authors and Affiliations

  1. First Affiliated Hospital of Chengdu Medical College, Chengdu, 610500, China

    Zhao Jing  (赵静), Wang Yi  (王轶), Yang Cui-rong  (杨翠蓉) & Lou Qing  (娄青)

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  1. Zhao Jing  (赵静)
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  2. Wang Yi  (王轶)
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  3. Yang Cui-rong  (杨翠蓉)
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  4. Lou Qing  (娄青)
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Correspondence to Lou Qing  (娄青).

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Author: Zhao Jing, bachelor, nurse

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The authors declare that there is no potential conflict of interest in this article.

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Informed consent was obtained from all individual participants.

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Jing, Z., Yi, W., Cui-rong, Y. et al. Therapeutic efficacy observation of acupuncture plus medicine for laryngopharyngeal reflux due to liver-qi stagnation and spleen deficiency. J. Acupunct. Tuina. Sci. 19, 226–230 (2021). https://doi.org/10.1007/s11726-021-1249-5

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  • DOI: https://doi.org/10.1007/s11726-021-1249-5

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