Clinical observation of heat-sensitive moxibustion for acute ischemic stroke

Abstract

Objective

To observe the clinical efficacy of heat-sensitive moxibustion in intervening acute ischemic stroke.

Methods

A total of 112 patients were divided into a control group and an observation group by the random number table method, with 56 cases in each group. The control group was treated with conventional treatment, and the observation group was treated with heat-sensitive moxibustion on the basis of the treatment in the control group. The National Institute of Health stroke scale (NIHSS) and modified Barthel index (MBI) were evaluated, and the intracranial hemodynamic indicators including mean velocity (Vm), pulsatility index (PI) and resistance index (RI) were recorded, and the serum levels of superoxide dismutase (SOD) and homocysteine (HCY) were measured before and after treatment. Clinical efficacy was evaluated after treatment.

Results

The total effective rate of the observation group was significantly higher than that of the control group (P<0.05). After treatment, the NIHSS scores in both groups decreased significantly (both P<0.05), and the MBI scores increased significantly (both P<0.05). The improvements of NIHSS and MBI scores in the observation group were superior to those in the control group (both P<0.05). Vm in both groups increased significantly (both P<0.05), PI and RI decreased (all P<0.05), and Vm, PI and RI in the observation group were superior to those in the control group (all P<0.05). The serum levels of SOD and HCY in the observation group were significantly improved, and were statistically different from those in the control group (both P<0.05).

Conclusion

Conventional treatment plus heat-sensitive moxibustion is effective in intervening acute ischemic stroke. It can promote the recovery of neurological function, improve daily activities, and improve intracranial blood flow, which may be related to the regulation of serum SOD and HCY levels.

【摘要】

目的: 观察热敏灸干预急性缺血性脑卒中的临床疗效。 方法: 将112例患者按随机数表法分为对照组和观察组, 每组56例。对照组予常规治疗, 观察组在常规治疗基础上加用热敏灸治疗。治疗前后评定美国国立卫生院卒中量表(NIHSS)及改良Barthel指数(MBI), 记录颅内血流动力学指标, 包括平均血流速度(Vm), 搏动指数(PI)及阻力指数(RI), 测定血清超氧化物歧化酶(SOD)及同型半胱氨酸(HCY)水平。治疗后评定疗效。 结果: 观察组总有效率明显高于对照组(P<0.05)。治疗后, 两组NIHSS评分均显著下降(均P<0.05), MBI评分均显著上升(均P<0.05), 观察组NIHSS及MBI评分改善情况均优于对照组(均P<0.05); 两组Vm明显升高(均P<0.05), PI及RI均降低(均P<0.05), 观察组Vm, PI及RI均显著优于对照组(均P<0.05); 观察组血清SOD和HCY水平明显改善, 且与对照组有统计学差异(均P<0.05)。结论: 常规治疗基础上加用热敏灸干预急性缺血性脑卒中疗效确切, 可促进患者神经功能的恢复, 提高日常活动能力, 改善颅内血流动力, 这可能与其调节血清SOD及HCY水平有关。