Effect of moxibustion at sensitized-acupoints on quality of life in patients with chronic superficial gastritis

Abstract

Objective

To compare the efficacy difference between moxibustion at sensitized-acupoints and non-sensitized-acupoints using the same group of acupoints.

Methods

A total of 139 patients with chronic superficial gastritis were divided into a sensitized acupoint group (102 cases) and a non-sensitized acupoint group (37 cases) based on whether acupoint sensitization occurred. The SPSS version 19.0 statistical software propensity score matching function was used to balance the baseline data between the groups. Finally, 29 pairs of matched patients were included, namely 29 cases in the sensitized acupoint group and 29 cases in the non-sensitized acupoint group. Both groups were treated with moxibustion therapy. The treatment lasted for 30 min per time, and was performed every other day for 8 weeks. Changes in the traditional Chinese medicine (TCM) symptom score and the short-form 36-item health survey (SF-36) score in both groups were observed before and after treatment, as well as the clinical efficacy.

Results

The covariates of age, course of disease, TCM symptom score and SF-36 score in the two groups were balanced after matching (all P<0.05). After treatment, the total effective rate was 100.0% in the sensitized acupoint group and 79.3% in the non-sensitized acupoint group. The difference in the total effective rate between the two groups was statistically significant (P<0.01). After treatment and at the 4-week follow-up, the TCM symptom scores in the sensitized acupoint group were significantly lower than those in the non-sensitized acupoint group (all P<0.01); the SF-36 scores in the sensitized acupoint group were significantly higher than those in the non-sensitized acupoint group (all P<0.01).

Conclusion

With the same group of acupoints, the sensitized acupoints have a better therapeutic effect and long-term efficacy than the non-sensitized acupoints in the treatment of chronic superficial gastritis.

摘要

目的:艾灸同一组腧穴, 比较穴位敏化与穴位非敏化之间的疗效差异。方法:将139 例慢性浅表性胃炎 患者依据是否出现穴位敏化, 分为穴位敏化组(102 例)和穴位非敏化组(37 例)。采用SPSS 19.0 统计软件倾向匹配 评分功能均衡组间基线资料, 最终纳入29 对匹配患者, 即穴位敏化组29 例和穴位非敏化组29 例。两组均采用 艾灸治疗, 每次30 min, 隔日1 次, 连续治疗8 周。观察两组治疗前后中医症状评分和简明健康测量量表(SF-36) 评分的变化, 并观察两组临床疗效。结果:两组患者年龄、病程、中医症状评分和SF-36 评分在组间不均衡的协 变量经匹配后均达到均衡(均P<0.05)。治疗后, 穴位敏化组总有效率为100.0%, 穴位非敏化组总有效率为79.3%, 两组比较差异有统计学意义(P<0.01)。治疗后与4 个月随访, 穴位敏化组中医症状评分均显著低于穴位非敏化组 (均P<0.01); 穴位敏化组SF-36 评分均显著高于穴位非敏化组(均P<0.01)。结论:同一组腧穴, 艾灸敏化态穴位 治疗慢性浅表性胃炎患者的临床疗效优于艾灸非敏化态穴位, 且远期疗效更好。