Skip to main content
Log in

Therapeutic efficacy observation on auricular point sticking therapy for cardiac syndrome X in women

耳穴贴压治疗女性心脏X综合征疗效观察

  • Clinical Study
  • Published:
Journal of Acupuncture and Tuina Science Aims and scope Submit manuscript

Abstract

Objective

To observe the clinical effect of auricular point sticking therapy for cardiac syndrome X (CSX) in women.

Methods

A total of 64 patients were randomized into two groups by the random number table, with 32 cases in each group. Patients in the control group received conventional treatment for angina, while patients in the treatment group received auricular point sticking therapy on the basis of conventional treatment. After 8 weeks of treatment, the levels of serum estradiol (E2), nitric oxide (NO) and endothelium-1 (ET-1) were compared to evaluate the therapeutic effect.

Results

After 8 weeks of treatment, the total effective rate and markedly effective rate in the treatment group were significantly higher than those in the control group, and the between-group comparisons showed statistical significance (both P<0.05). After treatment, the scores of chest pain and tightness in the control group dropped significantly, and the intra-group comparisons showed statistical significance (both P<0.05); the scores of chest pain and tightness, palpitations, weakness and shortness of breath in the treatment group dropped significantly, and the intra-group comparisons showed statistical significance (all P<0.05); there were significant inter-group differences in the scores of chest pain and tightness. After treatment, the intra-group comparisons of E2, NO and ET-1 contents in the control group showed no statistical significance (all P>0.05), while the E2, NO and ET-1 contents in the treatment group changed significantly after treatment and were significantly different from those in the control group (all P<0.05).

Conclusion

Auricular point sticking on the basis of conventional treatment was effective for CSX in women, and is worth clinical application.

摘要

目的

观察耳穴贴压对女性心脏X综合征(CSX)的临床疗效.

方法

将64例患者采用随机数字表法分为2组, 每组32例. 对照组接受心绞痛常规治疗; 治疗组在对照组治疗基础上加用耳穴贴压治疗. 治疗8周后比较两组临床疗效及血清学雌二醇(E2)、一氧化氮(NO)和血管收缩肽内皮素-1(ET-1)的变化.

结果

治疗8周后, 治疗组的总有 效率和显效率明显高于对照组, 组间差异均有统计学意义(均P<0.05).治疗后, 对照组胸痛和胸闷评分下降, 与本组治疗前均有统计学差异(均P<0.05); 治疗组胸痛、 胸闷、 心悸、 乏力及气短评分均下降, 与本组治疗前均有统计学差异(均P<0.05),胸痛和胸闷评分与对照组差异有统计学意义(均P<0.05). 治疗后, 对照组E2、 NO及ET-1含量与治疗前差异均无统计学意义(均P>0.05); 治疗组E2、 NO及ET-1与本组治疗前及对照组治疗后差异均有统计 学意义(均P<0.05).

结论

常规药物治疗基础上加耳穴贴压治疗女性CSX疗效确切, 值得临床推广.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Chen HZ. Practice of Internal Medicine. Beijing: People’s Medical Publishing House, 2005: 1471–1479.

    Google Scholar 

  2. Bai WL. Clinical study of estrogen deficiency and cardiac syndrome X in women. Zhongguo Yiyao Zhinan, 2014, 12(6): 235.

    Google Scholar 

  3. Hu YJ. Analysis of the clinical characteristics of women with cardiac syndrome X. Shenzhen Zhongxiyi Jiehe Zazhi, 2014, 24(7): 67–68.

    Google Scholar 

  4. He WK, Su Q, Liang JB, Wang XT, Sun YH, Li L. Nicorandil pretreatment inhibits myocardial apoptosis and improves cardiac function after coronary microemboli-zation in rats. J Geriatr Cardiol, 2018, 15(9): 591–597.

    CAS  PubMed  PubMed Central  Google Scholar 

  5. Chen Z, Chen X, Li S, Huo X, Fu X, Dong X. Nicorandil improves myocardial function by regulating plasma nitric oxide and endothelin-1 in coronary slow flow. Coron Artery Dis, 2015, 26(2): 114–120.

    Article  Google Scholar 

  6. Chinese Society of Cardiology. Editorial Board of Chinese Journal of Cardiovascular Disease. Diagnosis and treatment of chronic stable angina. Zhonghua Xinxueguanbing Zazhi, 2007, 35(3): 195–206.

    Google Scholar 

  7. Xue L. Interpretation of the European Society of Cardiology guidelines for the management of stable coronary artery disease, 2013. Lingnan Xinxueguanbing Zazhi, 2014, 20(2): 137–138.

    Google Scholar 

  8. Expert Committee on Rational Drug Use of National Health and Family Planning Commission. China Association of Pharmacists. Guidelines for rational drug use of coronary heart disease. Zhongguo Yixue Qianyan Zazhi (Dianzi Ban), 2016, 8(6): 19–108.

    Google Scholar 

  9. Ministry of Health of the People’s Republic of China. Guiding Principles for Clinical Study of New Chinese Medicines. Beijing: China Medical Science Press, 2002: 143–151.

    Google Scholar 

  10. State Administration of Traditional Chinese Medicine. Criteria of Diagnosis and Therapeutic Effects of Diseases and Syndromes in Traditional Chinese Medicine. Nanjing: Nanjing University Press, 2002: 29.

    Google Scholar 

  11. Zhou SH, Liu QM, Qi SS, Shen XQ, Zhao TS, Zhao SP, Gao M. The significance of the lipid profile and endothelium-dependence vasodilatation function in the pathogenesis of microvascular angina. Zhonghua Xinxueguanbing Zazhi, 2002, 30(5): 16–18.

    Google Scholar 

  12. Yang P, Qian FH, Qian YM. Relationship between coronary microcirculation dysfunction and microvascular angina. Hainan Yixue, 2015, 26(11): 1637–1639.

    CAS  Google Scholar 

  13. Qu FC, Lii L, Guo L, Gu Y, Zhang K, Wang AH. Relationship between sex hormones and ß-endorphin in postmenopausal women with cardiac syndrome X. Xin Yixue, 2014, 45(3): 182–185.

    Google Scholar 

  14. Du HB, Deng Y, Mou ZY. Theoretical discussion on correlation between coronary microvascular disease and collateral disease. Huanqiu Zhongyiyao, 2016, 9(6): 705–706.

    Google Scholar 

  15. Su TS, Lu J, Luo JH. Research progress on simultaneous dispersing phlegm and blood stasis for the treatment of cardiac syndrome X. Zhongxiyi Jiehe Xinnaoxueguanbing Zazhi, 2013, 11(5): 595–596.

    Google Scholar 

  16. Yu YT, Rong PJ, Zhu B. Present situation and prospect of transcutaneous auricular vagus nerve stimulation in encephalopathy treatment. Zhongguo Zhen Jiu, 2017, 37(3): 462–468.

    Google Scholar 

  17. Gao XY, Li YH, Zhu B, Ben H, Rong PJ. Effect of acupuncture of auricular concha area on blood pressure in spontaneous hypertension and normal rats and analysis on its mechanism. Zhen Ci Yan Jiu, 2006, 31(2): 90–95.

    Google Scholar 

  18. Huang F, Rong PJ, Wang HC, Meng H, Zhu B. Clinical observation on the intervention of auricular vagus nerve stimulation treating 35 cases of impaired glucose tolerance patients. Zhonghua Zhongyiyao Zazhi, 2010, 25(12): 2185–2186.

    CAS  Google Scholar 

  19. Zheng ZZ, Xia YQ, Zhu B, Wang HC. Clinical observation on the immediate reaction of sticking auricular vagus nerves for reducing high blood glucose. Zhongguo Zhen Jiu, 2008, 28(9): 702.

    Google Scholar 

  20. Rong PJ, Liu AH, Zhang JG, Wang YP, Yang AH, Ben H, Li L, Li LP, Song L, Liu HG, He W, Huang F, Li X, Liu RP, Wu P, Zhu B. Effect of transcutaneous auricular vagus nerve stimulation on refractory epileptic seizures. Shijie Kexue Jishu: Zhongyiyao Xiandaihua, 2013, 15(9): 2011–2020.

    Google Scholar 

  21. He W, Li YH, Rong PJ, Li L, Ben H, Zhu B. Effect of electroacupuncture of different regions of the auricle on epileptic seizures in epilepsy rats. Zhen Ci Yan Jiu, 2011, 36(6): 414–418.

    PubMed  Google Scholar 

  22. Liu RP, Rong PJ, Huang ZX, Ben H, Li L, Ma HM, Ma YG, Zhu B. Effect of electroacupuncture stimulation of auricular concha region at different time-points on behavior changes in depression rats. Zhen Ci Yan Jiu, 2012, 37(2): 131–135.

    PubMed  Google Scholar 

  23. Luo M, Qu XX, Li SY, Zhao JJ, Zhao YF, Jiao Y, Rong PJ. Transcutaneous vagus nerve stimulation for primary insomnia and affective disorder: a report of 35 cases. Zhongguo Zhen Jiu, 2017, 27(3): 269–273.

    Google Scholar 

  24. Fang JL, Hong Y, Fan YY, Liu J, Ma YY, Xu CH, Wang HH, Ma YG, Wang XL, Liu ZS, Zhu B, Kong J, Rong PJ. Brain response to transcutaneous electrical stimulation on auricular concha of the healthy subjects using iMRI. Cigongzhen Chengxiang, 2014, 5(6): 416–422.

    Google Scholar 

Download references

Acknowledgments

This work was supported by Scientific Research Fund of Hangzhou Red Cross Hospital, Zhejiang Province **, No. hhyn201702).

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Jun Wang  (王俊).

Ethics declarations

The authors declare that there is no conflict of interest.

Additional information

Statement of Informed Consent

Informed consent was obtained from all individual participants.

Author: Zhang Ya-mei, M.M., attending physician

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Zhang, Ym., Wang, J. Therapeutic efficacy observation on auricular point sticking therapy for cardiac syndrome X in women. J. Acupunct. Tuina. Sci. 18, 203–206 (2020). https://doi.org/10.1007/s11726-020-1172-1

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11726-020-1172-1

Keywords

关键词

中图分类号

文献标志码

Navigation