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Manipulation parameter optimization in Liu’s back tuina therapy for kids’ cough variant asthma in remission stage




To determine the optimal manipulation parameters in Liu’s back tuina therapy for remission-stage cough variant asthma (CVA) in kids.


A 5-factor 3-level L18(37) orthogonal design was adopted. The experimental factors and levels were selected: A, the number of times of Rou-kneading Feishu (BL 13); B, the frequency of Rou-kneading Feishu (BL 13); C, the number of times of Tui-pushing in a ‘介’-like pattern; D, the frequency of Tui-pushing in a ‘介’-like pattern; E, the intensity of red color after Ca-scrubbing Feishu (BL 13) with salt. A1, A2 and A3 stood for 10 times, 20 times and 30 times, respectively; B1, B2 and B3 stood for 200 times/min, 240 times/min and 280 times/min, respectively; C1, C2 and C3 stood for 50 times, 75 times and 100 times, respectively; D1, D2 and D3 stood for 150 times/min, 175 times/min and 200 times/min, respectively; E1, E2 and E3 stood for pinkish, bright red and dark red, respectively. A total of 108 kids with CVA in remission stage were divided into 18 groups using the random number table method, with 6 cases in each group. Changes in the cough score and fractional exhaled nitric oxide (FENO) level were observed after 15-day treatment.


The cough score and FENO level changed significantly in every group after treatment (all P<0.01). By the effect in improving cough score, the factors were listed as D, B, A, C and E in descending order; the most optimal manipulation parameter combination was group 17 (A3B2C1D3E1); the second optimal parameter combinations were group 7 (A3B1C2D1E3), group 13 (A2B1C2D3E1) and group 14 (A2B2C3D1E2). Regarding the effect in down-regulating the level of FENO, the factors were listed as C, A, E, B and D in descending order; the most optimal manipulation parameter combination was group 13 (A2B1C2D3E1); the second optimal parameter combinations were group 18 (A3B3C2D1E2), group 16 (A3B1C3D2E3) and group 14 (A2B2C3D1E2).


Two most effective manipulation parameter combinations were selected out of 18 different parameter combinations in Liu’s back tuina therapy for remission-stage CVA in kids. Doctors can choose an appropriate manipulation based on the symptom features of the disease.





应用5因素3水平 L18(37)正交设计方法, 筛选出试验因素和水平, A为揉肺俞操作次数, B为揉肺俞频率, C为推“介”字操作次数, D为推 “介”字频率, E为盐擦肺俞发红程度.3 A1、A2、A3分别为10次、20次和30次; B1、B2、B3分别为200次/分钟、 240次/分钟和280次/分钟; C1、C2、C3分别为50次、75次和100次; D1、D2、D3分别为150次/分钟、175次/分钟和 200次/分钟; E1、E2、E3分别为粉红、鲜红和紫红. 将108例缓解期CVA患儿按随机数字表法分为18组, 每组6例, 治 疗15 d后观察各组患儿的咳嗽症状评分和呼出气一氧化氮(FENO)水平变化.


治疗前后各组患儿咳嗽症状评 分和FENO水平同组比较, 差异均有统计学意义(均P<0.01). 在改善咳嗽症状评分方面, 作用主次关系由大到小依 次为D、B、A、C和E因素; 最好的手法操作参数为17组(A3B2C1D3E1); 较好的手法操作参数为7组(A3B1C2D1E3)、13 组(A2B1C2D3E1)和14组(A2B2C3D1E2). 在降低FENO水平方面, 作用主次关系由大到小依次为C、A、E、B和D因素; 最 好的手法操作参数为13组(A2B1C2D3E1); 较好的手法操作参数为18组(A3B3C2D1E2)、16组(A3B1C3D2E3)和14组 (A2B2C3D1E2).


刘氏推背法治疗儿童缓解期CVA的18种不同手法操作参数中, 筛选出2种临床疗效最好/较好 的手法操作参数组合, 医生可根据儿童缓解期CVA的具体症状特征, 采用较为合适的手法操作.

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This work was supported by Hunan Provincial Natural Science Foundation of China (湖南省自然科学基金, No. 20 17JJ3224); Key Project of Science and Technology Plan o f Hunan Province (湖南省科技计划重点项目, No. 2 015SK2034).

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Correspondence to Xiang-ning Shao.

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Informed consent was obtained from the guardians of the recruited children in this study.

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Li, X., Zhu, By. & Shao, Xn. Manipulation parameter optimization in Liu’s back tuina therapy for kids’ cough variant asthma in remission stage. J. Acupunct. Tuina. Sci. 18, 67–74 (2020).

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  • Tuina
  • Massage
  • Pediatric Tuina
  • Orthogonal Design
  • Cough
  • Asthma
  • Child, Preschool


  • 推拿
  • 按摩
  • 小儿推拿
  • 正交设计
  • 咳嗽
  • 哮喘
  • 儿童, 学龄前


  • R244.1


  • A