Skip to main content

Manipulation parameter optimization in Liu’s back tuina therapy for kids’ cough variant asthma in remission stage

刘氏推背法治疗缓解期儿童咳嗽变异性哮喘手法操作参数优化

Abstract

Objective

To determine the optimal manipulation parameters in Liu’s back tuina therapy for remission-stage cough variant asthma (CVA) in kids.

Methods

A 5-factor 3-level L18(37) orthogonal design was adopted. The experimental factors and levels were selected: A, the number of times of Rou-kneading Feishu (BL 13); B, the frequency of Rou-kneading Feishu (BL 13); C, the number of times of Tui-pushing in a ‘介’-like pattern; D, the frequency of Tui-pushing in a ‘介’-like pattern; E, the intensity of red color after Ca-scrubbing Feishu (BL 13) with salt. A1, A2 and A3 stood for 10 times, 20 times and 30 times, respectively; B1, B2 and B3 stood for 200 times/min, 240 times/min and 280 times/min, respectively; C1, C2 and C3 stood for 50 times, 75 times and 100 times, respectively; D1, D2 and D3 stood for 150 times/min, 175 times/min and 200 times/min, respectively; E1, E2 and E3 stood for pinkish, bright red and dark red, respectively. A total of 108 kids with CVA in remission stage were divided into 18 groups using the random number table method, with 6 cases in each group. Changes in the cough score and fractional exhaled nitric oxide (FENO) level were observed after 15-day treatment.

Results

The cough score and FENO level changed significantly in every group after treatment (all P<0.01). By the effect in improving cough score, the factors were listed as D, B, A, C and E in descending order; the most optimal manipulation parameter combination was group 17 (A3B2C1D3E1); the second optimal parameter combinations were group 7 (A3B1C2D1E3), group 13 (A2B1C2D3E1) and group 14 (A2B2C3D1E2). Regarding the effect in down-regulating the level of FENO, the factors were listed as C, A, E, B and D in descending order; the most optimal manipulation parameter combination was group 13 (A2B1C2D3E1); the second optimal parameter combinations were group 18 (A3B3C2D1E2), group 16 (A3B1C3D2E3) and group 14 (A2B2C3D1E2).

Conclusion

Two most effective manipulation parameter combinations were selected out of 18 different parameter combinations in Liu’s back tuina therapy for remission-stage CVA in kids. Doctors can choose an appropriate manipulation based on the symptom features of the disease.

摘要

目的

确定刘氏推背法治疗缓解期儿童咳嗽变异性哮喘(CVA)较佳手法操作参数.

方法

应用5因素3水平 L18(37)正交设计方法, 筛选出试验因素和水平, A为揉肺俞操作次数, B为揉肺俞频率, C为推“介”字操作次数, D为推 “介”字频率, E为盐擦肺俞发红程度.3 A1、A2、A3分别为10次、20次和30次; B1、B2、B3分别为200次/分钟、 240次/分钟和280次/分钟; C1、C2、C3分别为50次、75次和100次; D1、D2、D3分别为150次/分钟、175次/分钟和 200次/分钟; E1、E2、E3分别为粉红、鲜红和紫红. 将108例缓解期CVA患儿按随机数字表法分为18组, 每组6例, 治 疗15 d后观察各组患儿的咳嗽症状评分和呼出气一氧化氮(FENO)水平变化.

结果

治疗前后各组患儿咳嗽症状评 分和FENO水平同组比较, 差异均有统计学意义(均P<0.01). 在改善咳嗽症状评分方面, 作用主次关系由大到小依 次为D、B、A、C和E因素; 最好的手法操作参数为17组(A3B2C1D3E1); 较好的手法操作参数为7组(A3B1C2D1E3)、13 组(A2B1C2D3E1)和14组(A2B2C3D1E2). 在降低FENO水平方面, 作用主次关系由大到小依次为C、A、E、B和D因素; 最 好的手法操作参数为13组(A2B1C2D3E1); 较好的手法操作参数为18组(A3B3C2D1E2)、16组(A3B1C3D2E3)和14组 (A2B2C3D1E2).

结论

刘氏推背法治疗儿童缓解期CVA的18种不同手法操作参数中, 筛选出2种临床疗效最好/较好 的手法操作参数组合, 医生可根据儿童缓解期CVA的具体症状特征, 采用较为合适的手法操作.

This is a preview of subscription content, access via your institution.

References

  1. Miao Q, Wei PC, Fan MR, Zhang YP. Clinical study on treatment of cough variant asthma by Chinese medicine. Chin J Integr Med, 2013, 19(7): 539–545.

    Article  Google Scholar 

  2. Zhang ZW, Wang SC. Progress of TCM in the treatment of infantile cough variant asthma. Zhongyi Erke Zazhi, 2015, 11(6): 85–89.

    CAS  Google Scholar 

  3. Xue BC, Stephen OA, Wang HX, Li YP. Application Software for Diagnosis and Management of Cough Executive Summary: ACCP Evidence-based Clinical Practice Guidelines. Dalian: Abstracts of 2013 Annual Congress of Chinese Thoracic Society, 2013.

    Google Scholar 

  4. Liu YL, Tang SP, Dong L, Chen S, Hua YH, Chen L, Ye WJ, Zhang DY. The clinical characteristics and treatment status of chronic cough in children in Fuzhou area of Fujian province. Zhongguo Ertong Baojian Zazhi, 2016, 24(11): 1194–1196.

    Google Scholar 

  5. Clinical Research Coordination Group of the Causes Constituents Ratio of Chronic Cough in Chinese Children. Current status of chronic cough treatment in Chinese children. Zhonghua Erke Zazhi, 2014, 52(3): 163–171.

    Google Scholar 

  6. Tang W, Shao XN. Clinical experience of Xiangxi Liu’s infantile tuina for exogenous fever in children. J Acupunct Tuina Sci, 2018, 16(5): 310–314.

    Article  Google Scholar 

  7. Tang W, Shao XN, Zhang W, Ye Y, Li X, Zhu J, Tang LP, Yi XP. Characteristics of compound manipulation of the breast, back, and abdomen of Liu’s infantile tuina academic school in Xiangxi area. Zhongyiyao Daobao, 2017, 23(14): 38–39, 45.

    Google Scholar 

  8. Li X, Tang W, Ye Y, Tang LP, Yi XP, Ding JX, Zhu BY, Shao XN. Effect of Liu’s massage on the IL-4/STAT6 signal pathway in cough variant asthma rats. Zhongyiyao Daobao, 2017, 23(14): 19–22.

    CAS  Google Scholar 

  9. Wang WL, Zhang W, Jing L, Shen WD. Study on the orthogonal optimization of acupuncture, tuina and ultrasonic treatments for upper limb motor dysfunction after cerebral infarction. Shanghai Zhenjiu Zazhi, 2015, 34(5): 396–399.

    Google Scholar 

  10. Li PP, Yin D, Zhang P, Deng JL. Progress of clinical application of fractional exhaled nitric oxide for cough variant asthma in children. Yixue Zongshu, 2018, 24(22): 4497–4501.

    Google Scholar 

  11. Xu RQ. Pediatrics of Traditional Chinese Medicine. Beijing: People’s Medical Publishing House, 2013: 294.

    Google Scholar 

  12. Feng XC, Duan XZ, Sun LP, Lin SZ, Wang R, Liu J. Guideline for clinical diagnosis and treatment of pediatrics of traditional Chinese medicine: cough variant asthma in children (formulation). Zhongyi Erke Zazhi, 2016, 12(5): 1–4.

    Google Scholar 

  13. Li Y, Wang XJ. Therapeutic effect of wind cough prescription on cough variant asthma and its influence on eosinophils and immunoglobulin E. Zhongguo Zhongyiyao Xinxi Zazhi, 2013, 20(6): 5–7.

    Google Scholar 

  14. Shi P. Diagnosis and treatment of children cough. Zhongguo Quanke Yixue, 2010, 13(7): 745–747.

    Google Scholar 

  15. Shao XN. Inheritance of Liu’s Infantile Tuina. Beijing: People’s Medical Publishing House, 2017.

    Google Scholar 

  16. Cao GQ, Li XZ. Changes of fractional exhaled nitric oxide (FENO) level in hormone therapy for cough variant asthma and its relationship with airway inflammation. Neimenggu Yike Daxue Xuebao, 2018, 40(S1): 211–214.

    Google Scholar 

  17. Zhong D. Effect of Min Ke Jian on Airway Neurogenic Inflammation and Quality of Life in Patients with Yin Deficiency and Dryness Type Cough Variant Asthma. Chengdu: Doctor Thesis of Chengdu University of Traditional Chinese Medicine, 2014.

    Google Scholar 

  18. Ma HS, Zhang H, Miao ZJ, Yan JT, Tong XJ, Men ZT. Study on optimizing dynamics parameters in activating vital energy and blood circulation effects of rolling manipulation. Zhongguo Kangfu Yixue Zazhi, 2006, 21(12): 1116–1118.

    Google Scholar 

  19. Dong J. Effect of Fluticasone/Salmeterol on Exhaled Nitric Oxide in Cough Variant Asthma Patients. Jinan: Master Thesis of Shandong University, 2012.

    Google Scholar 

  20. Liu YL, Liu HT, Dong BQ, Song ST, Zhang SH, Tian H, Ma TM. Effects of acupuncture at Feishu (BL13) of rats on the potential amplitude and conduction time of the spinal nerve. Zhongguo Zhongyiyao Yuancheng Jiaoyu, 2018, 16(20): 92–95.

    Google Scholar 

  21. Wu ZL, Zhang QR. Ancient and modern studies on Feishu (BL 13). Liaoning Zhongyi Zazhi, 2007, 34(4): 504–505.

    CAS  Google Scholar 

  22. Li R, Yan ZY, Tang Y, Li WJ, Ren YL. Course of development of moxibustion on points Feishu (BL 13), Gaohuangshu (BL 43), Geshu (BL 17) and Danshu (BL 19) for treatment of the consumptive lung disease (interstitial pulmonary fibrosis). Zhongguo Zhen Jiu, 2004, 24(6): 61–63.

    Google Scholar 

  23. Wu YL, Zhang HL. Progress of diagnosis and treatment of cough variant asthma in children. Zhonghua Erke Zazhi, 2016, 54(4): 314–317.

    CAS  PubMed  Google Scholar 

  24. Ma HX. The Clinical Research on the Children with Remission Period Cough Variant Asthma Treatment with Yi Qi Jian Pi Theory of Traditional Chinese Medicine. Guangzhou: Master Thesis of Guangzhou University of Chinese Medicine, 2006.

    Google Scholar 

Download references

Acknowledgments

This work was supported by Hunan Provincial Natural Science Foundation of China (湖南省自然科学基金, No. 20 17JJ3224); Key Project of Science and Technology Plan o f Hunan Province (湖南省科技计划重点项目, No. 2 015SK2034).

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Xiang-ning Shao.

Additional information

Conflict of Interest

The authors declare that there is no potential conflict of interest in this article.

Statement of Informed Consent

Informed consent was obtained from the guardians of the recruited children in this study.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Li, X., Zhu, By. & Shao, Xn. Manipulation parameter optimization in Liu’s back tuina therapy for kids’ cough variant asthma in remission stage. J. Acupunct. Tuina. Sci. 18, 67–74 (2020). https://doi.org/10.1007/s11726-020-1159-y

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11726-020-1159-y

Keywords

  • Tuina
  • Massage
  • Pediatric Tuina
  • Orthogonal Design
  • Cough
  • Asthma
  • Child, Preschool

关键词

  • 推拿
  • 按摩
  • 小儿推拿
  • 正交设计
  • 咳嗽
  • 哮喘
  • 儿童, 学龄前

中图分类号

  • R244.1

文献标志码

  • A