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Therapeutic observation on acupuncture-moxibustion at different intervals for persistent allergic rhinitis

不同频次针灸治疗持续性变应性鼻炎的疗效观察

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Abstract

Objective: To observe the therapeutic effect of acupuncture-moxibustion at different intervals on persistent allergic rhinitis.

Methods: A total of 90 patients conforming to the inclusion criteria were randomized into three groups named A, B and C by randomized block method. Patients in all three groups received the same treatment of acupuncture and herbal cake-partitioned moxibustion at the same acupoints, while the treatment frequency was different. Patients in group A received the treatment once a week, group B twice a week and group C three times a week, and all the treatment lasted for 4 weeks. The total nasal symptom score (TNSS), total ocular symptom score (TOSS) and Sino-nasal outcome test-20 (SNOT-20) were evaluated before and after treatment. The self-rating score of symptoms was evaluated during treatment and 2 weeks after treatment.

Results: The total effective rate was 80.0% in group A, 93.3% in group B, and 100.0% in group C. The total effective rate in group A was statistically different from that in group B and group C (both P<0.05), but there was no significant inter-group difference in total effective rate between group B and group C (P>0.05). After treatment, scores of TNSS, TOSS and SNOT-20 in all three groups dropped significantly, and statistically different from those before treatment (all P<0.05); between-group comparison showed group B and group C decreased more obvious than group A (all P<0.05). In self-rating score of symptoms, there were no inter-group statistically significant differences in the first 3-week treatment (all P>0.05); after 4-week treatment, the score in group A was higher than that in group B and group C, and showed statistical significant (both P<0.05); at 2 weeks after treatment, the score in group A was higher than that in group B and group C based on an everyday record, showing statistical significance (both P<0.05). At the 11th day after treatment, the score in group B was higher than that in group C (P<0.05). There were no significant differences between group B and group C at other time points (all P>0.05).

Conclusion: All three protocols are effective for allergic rhinitis. With the increase of treatment frequency, the therapeutic efficacy with a treatment frequency of twice a week and three times a week is superior to that of once a week. Frequency of three times a week has a better long-term effect than once and twice a week, together with the least fluctuation of symptoms.

摘要

目的: 观察不同频次针灸治疗持续性变应性鼻炎的临床疗效。

方法: 将符合纳入标准的90例患者, 采用 随机区组法分为A组、B组和C组。三组治疗方法相同, 均采用相同穴位进行针刺和隔药饼灸, 但三组治疗频次不 同, A组每周治疗1次, B组每周治疗2次, C组每周治疗3次。三组均治疗4周。观察三组治疗后鼻部症状总评分(TNSS)、 眼部症状总评分(TOSS)和鼻腔鼻窦结局评分(SNOT-20)的变化。观察治疗期间及治疗结束后2周患者症状自主评分 变化。

结果: A组总有效率80.0%, B组总有效率93.3%, C组总有效率100.0%; A组总有效率与B、C组的差异均有统计 学意义(均P<0.05), B组和C组总有效率无统计学差异(P>0.05)。TNSS, TOSS和SNOT-20评分方面, 治疗后, 三组评分 均较同组治疗前降低, 组内差异有统计学意义(均P<0.05); 组间比较, B、 C两组评分较A组降低更明显(均P<0.05)。 症状自主评分方面, 治疗前3周三组评分无统计学差异(均P>0.05); 第4周时A组评分高于B组和C组, 组间差异有 统计学意义(均P<0.05); 治疗结束后2周A组每天的评分均高于B组和C组, 组间差异有统计学意义(均P<0.05); 治 疗结束后第11天B组高于C组(P<0.05), 其余时间B组和C组差异无统计学意义(均P>0.05)。

结论: 三种治疗频次对 于持续性变应性鼻炎患者均有效, 且随着治疗时间的累计, 每周2次及每周3次治疗的疗效优于每周1次。每周3次 较每周1次及每周2次更能维持疗效, 且治疗结束后患者症状波动最小。

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Acknowledgments

This work was supported by Shanghai Special Diagnosis and Treatment Project of Acupuncture-moxibustion (上海 市针灸特色诊疗项目, No. ZJ2016022); Construction Project of Acupuncture-moxibustion Specialty Alliance [针 灸专科联盟建设项目, No. ZY(2018-2020)-FWTX-4008].

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Authors and Affiliations

  1. Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200437, China

    Shuang Zhao  (赵爽), Meng-lu Qin  (秦梦璐), Qi Li  (李琪), Jing Li  (李璟) & Shen Li  (李申)

  2. Leshan Hospital of Chinese Medicine, Leshan, 614000, China

    Shuang Zhao  (赵爽)

  3. Wujing Hospital, Minhang District, Shanghai, Shanghai, 200241, China

    Qun Fan  (范群)

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  1. Shuang Zhao  (赵爽)
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Correspondence to Shen Li  (李申).

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Zhao, S., Fan, Q., Qin, Ml. et al. Therapeutic observation on acupuncture-moxibustion at different intervals for persistent allergic rhinitis. J. Acupunct. Tuina. Sci. 17, 409–415 (2019). https://doi.org/10.1007/s11726-019-1143-6

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  • DOI: https://doi.org/10.1007/s11726-019-1143-6

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