Skip to main content

Advertisement

Log in

Acupuncture treatment for depressive symptom in diarrhea-predominant irritable bowel syndrome: a randomized controlled study

针刺治疗腹泻型肠易激综合征抑郁症状的随机对照研究

  • Clinical Study
  • Published:
Journal of Acupuncture and Tuina Science Aims and scope Submit manuscript

Abstract

Objective: To observe the clinical efficacy of acupuncture treatment for depressive symptom in diarrhea-predominant irritable bowel syndrome (IBS-D).

Methods: A total of 70 patients with IBS-D accompanied by depressive symptom were randomized into a control group and an observation group, with 35 cases in each group. The control group was treated with oral intake of pinaverium bromide tablets, and the observation group was treated with regulating liver and spleen acupuncture treatment. The two groups were treated for 4 weeks. The scores of IBS symptom severity scale (IBS-SSS) and self-rating depression scale (SDS) were assessed before and after treatment.

Results: After treatment, there were statistical significant differences in the scores of abdominal pain degree, abdominal pain frequency and defecation satisfaction level and the total score between the two groups (all P<0.05). The SDS score of the observation group was obviously decreased, and the improvement was significantly superior to that in the control group (P<0.05).

Conclusion: Acupuncture treatment can significantly improve gastrointestinal symptom and depressive symptom in patients with IBS-D.

摘要

目的: 观察针刺治疗腹泻型肠易激综合征抑郁症状的临床疗效。

方法: 将70例腹泻型肠易激综合征伴抑 郁症状的患者随机分为对照组和观察组, 每组35例。对照组给予匹维溴铵片口服, 观察组给予调肝脾针刺治疗。两组均治疗4周。治疗前及治疗后评定肠易激综合征症状严重程度量表(IBS-SSS)及抑郁自评量表(SDS)。

结果: 治 疗后, 两组腹痛程度、腹痛频率、排便满意度的评分及总分的差异均有统计学意义(均P&#xFF1C;0.05); 观察组的SDS评分 明显降低, 且改善程度明显优于对照组(P&#xFF1C;0.05)。

结论: 针刺能显著改善腹泻型肠易激综合征患者的胃肠道症状 及抑郁症状。

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Gao J. Correlation between anxiety-depression status and cytokines in diarrhea-predominant irritable bowel syndrome. Exp Ther Med, 2013, 6(1): 93–96.

    Article  CAS  Google Scholar 

  2. Zhang BB, Zhang PP. Acupuncture treatment of 34 cases with IBS-D by invigorating the spleen and dispersing the stagnated liver-energy. Jiangxi Zhongyiyao, 2014, 45(7): 60–62.

    CAS  Google Scholar 

  3. Chey WD, Kurlander J, Eswaran S. Irritable bowel syndrome: a clinical review. JAMA, 2015, 313(9): 949–958.

    Article  CAS  Google Scholar 

  4. Kabra N, Nadkarni A. Prevalence of depression and anxiety in irritable bowel syndrome: a clinic based study from India. Indian J Psychiatry, 2013, 55(1): 77–80.

    Article  Google Scholar 

  5. Zhu FF, Ye B. Current state of the treatment and pathogenesis of diarrhea irritable bowel syndrome. Xibu Zhongyiyao, 2013, 26(10): 139–142.

    Google Scholar 

  6. Yang M, Zhou L, Xu PD, Huang R. Clinical study of acupuncture-moxibustion for diarrhea-predominant irritable bowel syndrome. Shanghai Zhenjiu Zazhi, 2018, 37(11): 1246–1249.

    Google Scholar 

  7. Yang LJ, Wang XX, Li B, Wang SB, Zhang S, Jing ZG, Shao R, Wang Y. Effect of acupuncture on the acupoint pain threshold in patients with irritable bowel syndrome. Shanghai Zhenjiu Zazhi, 2018, 37(9): 1030–1036.

    Google Scholar 

  8. Shu Y Y. The effects of warm acupuncture combined with acupuncture on defecation and emotion in patients with diarrhea-predominant irritable bowel syndrome. Taishan Yixueyuan Xuebao, 2018, 39(7): 785–787.

    Google Scholar 

  9. Vork L, Weerts ZZRM, Mujagic Z, Kruimel JW, Hesselink MAM, Muris JWM, Keszthelyi D, Jonkers DMAE, Masclee AAM. Rome III vs Rome IV criteria for irritable bowel syndrome: a comparison of clinical characteristics in a large cohort study. Neurogastroenterol Motil, 2017: e13189.

    Google Scholar 

  10. Zheng X Y. Guiding Principles for Clinical Research of New Drugs in Traditional Chinese Medicine. Beijing: China Medical Science Press, 1992: 364–366.

    Google Scholar 

  11. Betz C, Mannsdörfer K, Bischoff SC. Validation of the IBS-SSS. Z Gastroenterol, 2013, 51(10): 1171–1176.

    Article  CAS  Google Scholar 

  12. Jasper F, Egloff B, Roalfe A, Witthöft M. Latent structure of irritable bowel syndrome symptom severity. World J Gastroenterol, 2015, 21(1): 292–300.

    Article  Google Scholar 

  13. Mercincavage M, Smyth JM, Branstetter SA, Catley D. Exploring the severity of dependence scale (SDS) as a possible measure of nicotine dependence. Subst Abus, 2016, 37(2): 323–329.

    Article  Google Scholar 

  14. Lin CH, Lu MJ, Wong J, Chen CC. Comparison of physician-rating and self-rating scales for patients with major depressive disorder. J Clin Psychopharmacol, 2014, 34(6): 716–721.

    Article  Google Scholar 

  15. Li HL, Ren W, Li YM, Yuan F, Yao SK. The advances on the pathogenic factor and pathogenesis of irritable bowel syndrome. Yixue Yu Zhexue, 2017, 38(4): 73–76.

    Google Scholar 

  16. Huang KY, Liang S, Fu SP, Yu ML, Lu SF. Application of gastrointestinal adjustment in the treatment of encephalopathy with acupuncture and moxibustion: based on the theory of axis of brain and intestines. Zhongyi Zazhi, 2016, 57(13): 1099–1104.

    Google Scholar 

  17. Holzer P, Farzi A. Neuropeptides and the microbiota-gut-brain axis. Adv Exp Med Biol, 2014, 817: 195–219.

    Article  CAS  Google Scholar 

  18. Daulatzai MA. Chronic functional bowel syndrome enhances gut-brain axis dysfunction, neuroinflammation, cognitive impairment, and vulnerability to dementia. Neurochem Res, 2014, 39(4): 624–644.

    Article  CAS  Google Scholar 

  19. Kohman RA, Rhodes JS. Neurogenesis, inflammation and behavior. Brain Behav Immun, 2013, 27(1): 22–32.

    Article  CAS  Google Scholar 

  20. Zhan DW, Sun JH, Luo KT, Xu LZ, Zhou JL, Pei LX, Chen L, Wu XL, Zhang JW. Effects and efficacy observation of acupuncture on serum 5-HT in patients with diarrhea-predominant irritable bowel syndrome. Zhongguo Zhen Jiu, 2014, 34(2): 135–138.

    CAS  PubMed  Google Scholar 

  21. Zhu LL, Zhang YY, Cao Y, Wang HB. Acupoints selection pattern in acupuncture-moxibustion treatment of perimenopausal syndrome from 2007 to 2016. J Acupunct Tuina Sci, 2017, 15(6): 403–409.

    Article  Google Scholar 

Download references

Acknowledgments

This work was supported by Shaoxing No. 2 Hospital.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Guo-juan Meng  (孟国娟).

Additional information

Conflict of Interest

The author declared that there was no potential conflict of interest in this article.

Statement of Informed Consent

Informed consent was obtained from all individual participants.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Meng, Gj. Acupuncture treatment for depressive symptom in diarrhea-predominant irritable bowel syndrome: a randomized controlled study. J. Acupunct. Tuina. Sci. 17, 422–426 (2019). https://doi.org/10.1007/s11726-019-1138-3

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11726-019-1138-3

Keywords

关键词

中图分类号

文献标志码

Navigation