Therapeutic observation of Tui-pushing Wujing plus Chinese patent medicine for infantile diarrhea due to spleen deficiency

Abstract

Objective: To observe the therapeutic efficacy of pediatric tuina plus Chinese patent medicine for preschool kids with diarrhea due to spleen deficiency.

Methods: Ninety-two eligible kids were divided into a tuina plus Chinese patent medicine and a Chinese patent medicine group by the random number table, with 46 cases in each group. The Chinese patent medicine group was intervened by oral administration of Qi Wei Bai Zhu San (Seven-ingredient Atractylodes Macrocephala Powder); the tuina plus Chinese patent medicine group was additionally given pediatric tuina therapy once a day, 20 min each time. Efficacy and safety were evaluated after 7-day treatment in both groups, and a 14-day follow-up was conducted.

Results: After treatment, the symptom scores all changed significantly in the two groups (all P<0.05). After intervention, the symptom scores in the tuina plus Chinese patent medicine group were significantly different from those in the Chinese patent medicine group (all P<0.05). The total effective rate was 78.3% in the Chinese patent medicine group, versus 89.1% in the tuina plus Chinese patent medicine group, and the between-group difference was statistically significant (P<0.05). Three cases got a relapse in the Chinese patent medicine group, versus one case in the tuina plus Chinese patent medicine group, and the between-group difference was statistically insignificant (P>0.05). The two groups each had one case of vomiting, which were treated properly and turned better. No other adverse reactions occurred.

Conclusion: Tuina plus Chinese patent medicine and Chinese patent medicine alone both are effective for diarrhea due to spleen deficiency in kids, but the combined therapy can produce more significant efficacy.

摘要

目的:观察小儿推拿结合中药治疗学龄前儿童脾虚腹泻的疗效。方法:选择符合纳入标准的脾虚腹泻患 儿92例, 根据随机数字表分为推拿加中药组和中药组, 每组46例。中药组采用口服七味白术散治疗; 推拿加中药 组在服用相同中药的基础上加用小儿推拿治疗。小儿推拿每日1次, 每次20 min。两组均治疗7 d后进行疗效观察 和安全性评价, 治疗14 d后随访复发情况。结果:治疗后, 两组各类症状评分与同组治疗前均有统计学差异(均 P<0.05)。推拿加中药组治疗后各类症状评分与中药组比较均有统计学差异(均P<0.05)。中药组总有效率78.3%, 推拿加中药组总有效率89.1%, 组间差异有统计学意义(P<0.05)。中药组复发3例, 推拿加中药组复发1例, 组间差 异无统计学意义(P>0.05)。两组均有1例出现呕吐, 经处理后好转, 未出现其他明显不良反应。结论:推拿加中药 及单独中药治疗对儿童脾虚腹泻均有效, 推拿加中药治疗的疗效优于单独中药口服。