Abstract
Objective
To observe the clinical efficacy of auricular point pricking-bloodletting plus auricular point sticking therapy for acne vulgaris.
Methods
A total of 66 patients with acne vulgaris were randomized into an observation group and a control group by the random number table, with 33 cases in each group. The observation group was treated with auricular point pricking-bloodletting plus auricular point sticking therapy, and the control group was treated only with auricular point sticking therapy. The treatments of both groups were performed twice a week, 4 weeks as a course of treatment, for 3 courses in total. The scores of skin lesions and dermatology life quality index (DLQI) scores were recorded before and after treatment to assess the clinical efficacy.
Results
During the trial, there were 3 cases of drop-out both in the observation group and the control group. After 3 courses of treatment, the total effective rate of the observation group was 96.7%, while that of the control group was 76.7%. The difference between the two groups was statistically significant (P<0.05). The intra-group comparison showed that the scores of skin lesion and DLQI were both decreased with the increase of treatment times, that was, the scores were lower than those at the previous time point (all P<0.05). After 1, 2, and 3 courses of treatment, the scores of skin lesion and DLQI of both groups were statistically different from those of the same group before treatment (all P<0.05). At every time point during the treatment, the scores of skin lesion and DLQI of the observation group were lower than those of the control group, and the differences between the two groups were statistically significant (all P<0.05).
Conclusion
Auricular point pricking-bloodletting plus auricular point sticking has a better curative effect than auricular point sticking therapy alone in the treatment of acne vulgaris, and has a time-effect correlation.
摘要
目的
观察耳穴刺络放血加耳穴贴压治疗寻常性痤疮的临床疗效.
方法
将66例寻常性痤疮患者根据随机数字表分为观察组和对照组, 每组33例. 观察组采用耳穴刺络放血加耳穴贴压治疗, 对照组仅采用耳穴贴压治疗. 两组均每周治疗2次, 4周为1个疗程, 共治疗3个疗程. 分别于治疗前和治疗后记录患者皮损积分和皮肤病生活质量指数(DLQI)积分, 并据此进行疗效评定.
结果
试验过程中观察组和对照组均脱落3例. 3个疗程结束后, 观察组总有效率为96.7%; 对照组总有效率为76.7%, 差异有统计学意义(P<0.05). 组内比较显示, 两组患者皮损积分和DLQI积分均随治疗次数的增加而降低, 后一时间点积分均低于前一时间点(均P<0.05). 两组患者治疗1、2、3个疗程后的皮损积分和DLQI积分均与本组治疗前比较有统计学差异(均P<0.05). 组间比较显示, 治疗后每个时间点, 观察组皮损积分与DLQI积分均低于对照组, 组间差异均有统计学意义(均P<0.05).
结论
耳穴刺络放血加耳穴贴压治疗寻常性痤疮的临床疗效优于单独耳穴贴压治疗, 且存在时间-效应关系.
Similar content being viewed by others
References
Wu YN, Bai MJ, Wang YQ, Zhang Z, Yu XJ. Study on regularities in acupoint selection for acupuncture treatment of acne. Shanghai Zhenjiu Zazhi, 2018, 37(6): 695–700.
Gu W, Zhang XQ, Wu JD. Characteristics of Chinese medicine treatment of acne from etiology and pathogenesis of traditional Chinese medicine. Liaoning Zhongyi Zazhi, 2016, 43(4): 739–742.
Li T. Investigation on Treatment of Acne Vulgris by Ear-acupuncture. Guangzhou: Master Thesis of Guangzhou University of Chinese Medicine, 2016.
Li YX. Therapeutic observation on 54 cases of bloodletting at otopoint for acne. Yixue Lilun Yu Shijian, 2008, 21(4): 446–447.
Cheng L. Clinical study and nursing guidance of 50 cases with acne vulgaris treated by bean-pressing at ear points. Qilu Huli Zazhi, 2010, 16(11): 39–40.
She YF, Sun LH, Yang JJ. Clinical observation of 32 cases with acne treated by bloodletting. Hebei Zhongyiyao Xuebao, 2008, 23(3): 37–38.
Chinese Acne Treatment Guidelines Expert Group. Guideline for diagnosis and treatment of acne (the 2014 revised edition). Linchuang Pifuke Zazhi, 2015, 44(1): 52–57.
State Administration of Traditional Chinese Medicine. Criteria of Diagnosis and Therapeutic Effects of Diseases and Syndromes in Traditional Chinese Medicine. Nanjing: Nanjing University Press, 1994: 282.
General Administration of Quality Supervision, Inspection and Quarantine of the People’s Republic of China, Standardization Administration of the People’s Republic of China. Nomenclature and Location of Auricular Points (GB/T 13734-2008). Beijing: Standards Press of China, 2008.
Feng N, Wu LP. Treatment of 45 female cases with facial acne by bloodletting at otopoint Cheek (LO5). Zhongguo Zhen Jiu, 1996, 16(11): 49.
Liu JH, Chen YE, Song SY, Chen SH, Xuan TH, Pan ZB. Observations on the efficacy of multi-functional fire needling plus auricular plaster therapy for moderate to severe acne vulgaris. Shanghai Zhenjiu Zazhi, 2016, 35(5): 555–557.
Ministry of Health of the People’s Republic of China. Guiding Principles for Clinical Study of New Chinese Medicines. Beijing: China Medical Science Press, 2002: 292–295.
Li YZ, Jiang CH, Li P. Clinical observation and quality of life assessment of acne treated by external treatment of traditional Chinese medicine. Shaanxi Zhongyiyao Daxue Xuebao, 2016, 39(3): 63–65.
Wei HY, Zhang HM, Zhao L, Wang SA. Research review of instant effect of auricular therapy. Zhongguo Zhongyiyao Xinxi Zazhi, 2015, 22(12): 124–126.
Qian LL, He LZ, Li JW, Zhang H. Clinical study of the immediate hypoglycemic effect of combined ear point therapy. Shanghai Zhenjiu Zazhi, 2016, 35(11): 1296–1298.
Du CH. Exploration of the distribution regularities of auricular points based on bio-holographic law. Zhongguo Zhen Jiu, 1997, 17(5): 308–311.
Lu XY. The development of auricle and inversion of the distribution of auricular points. Shanghai Zhenjiu Zazhi, 2017, 36(7): 866–869.
Zhou XL, Zhou J. Diagram for Auricular Diagnosis and Treatment. Shenyang: Liaoning Science and Technology Publishing House, 2006: 5–7.
Wu YN, Bai MJ, Wang YQ, Zhang Z, Yu XJ. Study on regularities in acupoint selection for acupuncture treatment of acne. Shanghai Zhenjiu Zazhi, 2018, 37(6): 695–700.
Li WR, Li B, Guo Y, Zhao TY, Guo Y, Chen ZL. Study on ancient medical records of bloodletting puncture therapy. Liaoning Zhongyi Zazhi, 2018, 45(5): 1038–1041.
Du YZ. Research on Regularities and Characteristics of Acne Treated by Blood-letting Therapy Based on Data Mining. Shijiazhuang: Master Thesis of Hebei Medical University, 2014.
Chen LH, Jin S, Hu YP. Clinical research progress of pricking bloodletting and cupping for acne. Zhongyiyao Xuekan, 2006, 24(4): 689–690.
Hou PW, Hsu HC, Lin YW, Tang NY, Cheng CY, Hsieh CL. The history, mechanism, and clinical application of auricular therapy in traditional Chinese medicine. Evid Based Complement Alternat Med, 2015, 2015: 495684.
Hong TT, Wu LX. Clinical observation on pricking bloodletting therapy at Back-Shu acupoints plus Chinese herbal mask in treating patients with acne. J Acupunct Tuina Sci, 2013, 11(5): 286–288.
Yang L, Yuan XL. The mechanism and research progress of pricking bloodletting therapy. Ya Tai Chuantong Yiyao, 2016, 12(2): 67–69.
Ma Y, Xiang LH. The new understanding of the pathogenesis of acne and treatment goals. Linchuang Pifuke Zazhi, 2015, 44(1): 66–69.
Acknowledgments
This work was supported by National Natural Science Foundation of China (国家自然科学基金, No. 81573884); Undergraduate Innovation and Entrepreneurship Training Programs of Hebei University of Chinese Medicine (河北中医学院“大学生创新创业训练计划”).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Song, Yj., Fan, Xs., Li, My. et al. Treatment of acne vulgaris with auricular acupoint pricking-bloodletting plus auricular point sticking therapy: a randomized controlled study. J. Acupunct. Tuina. Sci. 17, 196–202 (2019). https://doi.org/10.1007/s11726-019-1112-0
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11726-019-1112-0
Keywords
- Acupoint Therapy
- Auricular Point Sticking
- Bloodletting Therapy
- Otopoint, Cheek (LO5)
- Point, Erjian (EX-HN 6)
- Otopoint, Lung (CO14)
- Otopoint, Shenmen (TF4)
- Acne