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Effect of mild-warm moxibustion on fatigue, immune state and quality of life in sub-health population

温和灸对亚健康人群疲劳、免疫状态及生存质量的影响

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Abstract

Objective

To observe the effect of mild-warm moxa stick moxibustion on fatigue, immune state and quality of life (QOL) in sub-health population.

Methods

A total of 120 cases were randomly allocated into a moxibustion group ((n=60) and a Chinese patent medicine (CPM) group (n=60). People in the moxibustion group were intervened with mild-warm moxa stick moxibustion, once a day; while people in the control group took oral Bu Zhong Yi Qi Wan (Spleen/stomach-supplementing and Qi-boosting Pill), 3 doses a day. Two months made up a course of treatment. The fatigue, immune state and QOL were then observed after one treatment course, followed by a 12-month follow-up.

Results

A total of 115 cases completed the clinical trial. After intervention, the fatigue scores, immune parameters and QOL scores were significantly increased in both groups, showing statistical significances (P<0.05). There were between-group significant differences in fatigue score, levels of immunoglobulin M (IgM) and IgG, natural killer (NK) cell activity and QOL score (P<0.05). After the 12-month follow-up, there were still significant between-group differences in fatigue score, physical health, psychological, social relationships and overall perception of QOL and overall perception of health (P<0.05).

Conclusion

Mild-warm moxibustion can markedly improve the fatigue, immune state and QOL in sub-health population.

摘要

目的

探讨艾条温和灸对疲劳性亚健康人群疲劳、免疫状态及生存质量的影响。

方法

将120 例患者按照就诊顺序随机分为艾灸组和中药组, 每组60 例。艾灸组采用艾条温和灸干预, 1 次/d, 中药组给予补中益气丸口服, 3 次/d, 连续治疗2 个月为1 个疗程。两组均在治疗1 疗程后观察患者疲劳、免疫状态及生存质量, 并随访12 个月。

结果

共115 例患者完成了临床试验, 两组患者治疗后疲劳评分、免疫学指标及生存质量评分与治疗前比较均显著改善, 差异均有统计学意义(P<0.05)。艾灸组患者治疗后疲劳评分, 免疫球蛋白M(immunoglobulin M, IgM)、IgG 含量及自然杀伤 (natural killer, NK)细胞活性, 生存质量评分与中药组差异比均有统计学意义(P<0.05)。12 个月随访结束时艾灸组患者疲劳评分及生理、心理、社会关系、生存质量主观感觉、健康状况主观感觉评分与中药组均有统计学差异(P<0.05)。

结论

温和灸可明显改善疲劳性亚健康人群的疲劳症状、免疫状态与生活质量。

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Authors and Affiliations

  1. Anhui University of Chinese Medicine, Hefei, 230038, China

    Rong-lin Cai  (蔡荣林), Ling Hu  (胡玲), Zi-hui Li  (李姿慧), Meng Li  (李梦) & Zi-jian Wu  (吴子建)

  2. Anhui Provincial Hospital of Acupuncture-moxibustion, Hefei, 230061, China

    Hong-liang Cheng  (程红亮)

  3. Anhui Provincial Hospital of Traditional Chinese Medicine, Hefei, 230031, China

    Wu-bin Hu  (胡吴斌)

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  1. Rong-lin Cai  (蔡荣林)
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  2. Ling Hu  (胡玲)
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  3. Zi-hui Li  (李姿慧)
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  4. Meng Li  (李梦)
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  6. Zi-jian Wu  (吴子建)
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Correspondence to Rong-lin Cai  (蔡荣林).

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Cai, Rl., Hu, L., Li, Zh. et al. Effect of mild-warm moxibustion on fatigue, immune state and quality of life in sub-health population. J. Acupunct. Tuina. Sci. 14, 82–86 (2016). https://doi.org/10.1007/s11726-016-0905-7

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  • DOI: https://doi.org/10.1007/s11726-016-0905-7

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