Clinical study on acupuncture for quality of life in patients with age-related macular degeneration

Abstract

Objective

To observe the effect of acupuncture on the quality of life in patients with age-related macular degeneration (AMD).

Methods

A total of 47 dry AMD cases (94 eyes) were randomly allocated into three groups, 22 cases (44 eyes) in the acupuncture group, 15 cases (30 eyes) in the Western medicine group and 10 cases (20 eyes) in the control group. Cases in the acupuncture group were treated with acupuncture, cases in the Western medicine group with vitamin C and E and cases in the control group received no treatment except for out-patient follow-up.

Results

Acupuncture could significantly improve eye symptoms of dry AMD cases including blurred vision, drastic decrease in visual acuity, distorted vision, central scotomas, visual fatigue and dry eyes as well as other systemic symptoms related to macular degeneration.

Conclusion

Acupuncture can substantially improve the quality of life in patients with dry AMD.

This is a preview of subscription content, log in to check access.

References

  1. [1]

    Gu H, Liu NP. Progress in genetic studies of age-related macula degeneration. Zhonghua Yanke Zazhi, 2012, 48(2): 176–178.

    CAS  Google Scholar 

  2. [2]

    Xu D, Cai YS. Biology of free radicals and pathomechanism of eye tissue injury. Foreign Medical Science (Section of Ophthalmology), 1997, (3): 131–133.

    Google Scholar 

  3. [3]

    Yoshida A, Yoshida M, Yoshida S, Shiose S, Hiroishi G, Ishibashi T. Familial cases with age-related macular degeneration. Jpn J Ophthalmol, 2000, 44(3): 290–295.

    PubMed  Article  CAS  Google Scholar 

  4. [4]

    Yu J, Wu LZ, Xu L. Preliminary study of mitochondrial DNA deletions in age-related macular degeneration. Yanke Xuebao, 1997, 13(2): 52–55.

    CAS  Google Scholar 

  5. [5]

    Allikmets R, Shroyer NF, Singh N, Seddon JM, Lewis RA, Bernstein PS, Peiffer A, Zabriskie NA, Li Y, Hutchinson A, Dean M, Lupski JR, Leppert M. Mutation of the Stargardt disease gene (ABCR) in age-related macular degeneration. Science, 1997, 277(5333): 1805–1807.

    PubMed  Article  CAS  Google Scholar 

  6. [6]

    Bernstein PS, Leppert M, Singh N, Dean M, Lewis RA, Lupski JR, Allikmets R, Seddon JM. Genotype-phenotype analysis of ABCR variants in macular degeneration probands and siblings. Invest Ophthalmol Vis Sci, 2002, 43(2): 466–473.

    PubMed  Google Scholar 

  7. [7]

    Kliffen M, Lutgens E, Daemen MJ, de Muinck ED, Mooy CM, de Jong PT. The APO*E3-Leiden mouse as an animal model for basal laminar deposit. Br J Ophthalmol, 2000, 84(2): 1415–1419.

    PubMed  Article  CAS  Google Scholar 

  8. [8]

    Hui YN. Ophthalmology. 6th edition. People’s Medical Publishing House, 2004: 176–177.

    Google Scholar 

  9. [9]

    General Administration of Quality Supervision, Inspection and Quarantine of the People’s Republic of China, Standardization Administration of the People’s Republic of China. Nomenclature and Location of Acupuncture Points (GB/T 12346-2006). Standards Press of China, 2006.

  10. [10]

    Zhang B, Peng L, Zhou LZ, Mu JP, Cheng JM. Observation on the therapeutic efficacy of moxibustion and acupoint injection in treating optic atrophy. Shanghai Zhenjiu Zazhi, 2012, 31(11): 833–834.

    Google Scholar 

  11. [11]

    Zhang CH, Zhang LL, Ma XP, Yang L, Hong J, Liu J, Wu LX. Research on acupuncture-moxibustion for dry eye syndrome. J Acupunct Tuina Sci, 2013, 11(2): 72–78.

    Article  CAS  Google Scholar 

  12. [12]

    Tao XY, Ru K, Lang S, Zhu WL, Fu J, Chen J, Ye C, Tao Y, Li Y, Yu YH. Observations on the efficacy of acupuncture at periocular extraordinary points in treating juvenile myopia. Shanghai Zhenjiu Zazhi, 2010, 29(10): 643–644.

    Google Scholar 

  13. [13]

    Guo MH, Cui EC, Li XY, Zong L. Diverse needling methods for dry eye syndrome: a randomized controlled study. J Acupunct Tuina Sci, 2013, 11(2): 84–88.

    Article  Google Scholar 

  14. [14]

    Ren H. Observations on the efficacy of point injection in treating 76 acquired abducent paralysis patients. Shanghai Zhenjiu Zazhi, 2008, 27(1): 11–12.

    Google Scholar 

  15. [15]

    Xia Y, Shu S, Li Y, Liu SM, He JS. Therapeutic effect and side effect of treatment on hyperthyroid exophthalmos with the combination of acupuncture and medication. Zhongguo Zhenjiu, 2010, 30(10): 806–809.

    Google Scholar 

Download references

Author information

Affiliations

Authors

Corresponding author

Correspondence to Shi-min Liu.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Xia, Y., Liu, R., Sun, J. et al. Clinical study on acupuncture for quality of life in patients with age-related macular degeneration. J. Acupunct. Tuina. Sci. 11, 358–362 (2013). https://doi.org/10.1007/s11726-013-0732-z

Download citation

CLC Number

  • R246.82

Key Words

  • Acupuncture Therapy
  • Age-related Macular Degeneration
  • Quality of Life