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Quantity-effect relationship of electroacupuncture for urge incontinence: A multicenter randomized controlled trial

电针治疗急迫性尿失禁量效关系的多中心随机对照试验

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Journal of Acupuncture and Tuina Science Aims and scope Submit manuscript

摘要

目的

观察电针治疗急迫性尿失禁 (Urge Incontinence, UI)的量效关系。

方法

采用多中心临床随机、 对照的研究方法, 选取符合纳入标准的UI患者199 例, 按2: 1比例随机分入针刺组和药物组。 针刺组131 例, 采用电针结合手捻针治疗; 药物组68 例, 采用口服酒石酸托特罗定片治疗。

结果

治疗后, 两组患者国际尿失禁咨询委员会尿失禁问卷表(International Consultation on Incontinence Questionnaire-short Form (ICIQ-SF) 评分结合国际前列腺症状评分(International Prostatic Symptom Score, I-PSS) 的总分数在每个访视点(治疗3 次、 6 次、 9 次)均较治疗前明显改善, 并且随着治疗次数的增加效果呈累积效应, 且针刺组改善效应在每个访视点均明显优于药物组(P<0.05)。

结论

电针加手捻针及口服酒石酸托特罗定片治疗对UI的排尿症状改善程度与治疗次数呈正相关, 且以针刺方法效果更显著。

Abstract

Objective

To investigate the quantity-effect relationship of electroacupuncture in treating urge incontinence (UI).

Methods

A clinical multicenter randomized controlled trial was carried out. One hundred and ninety-nine UI patients meeting the inclusion criteria were randomly allocated, at a ratio of 2:1, to acupuncture and medication groups. The acupuncture group of 199 patients was treated with electroacupuncture plus manual acupuncture, and the medication group of 68 patients was treated with oral administration of Tolterodine Tartrate tablets.

Results

The total scores of international consultation on incontinence questionnaire-short form (ICIQ-SF) score plus the international prostatic symptom score (I-PSS) were significantly lower in both groups at each follow-up visit (after 3, 6 and 9 treatments) than before treatment. The effect was accumulated with an increase in the number of treatments. The improving effect was significantly better at each follow-up visit in the acupuncture group than that in the medication group (P<0.05).

Conclusion

The improvement degree of urinary symptoms and the number of treatments are positively correlated in the treatment of UI by electroacupuncture plus manual acupuncture and by oral administration of Tolterodine Tartrate tablets. Acupuncture has a more marked effect.

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Authors and Affiliations

  1. Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, P. R. China

    Qi-fan Feng  (冯琦钒), Yu-lin Fu  (傅御麟), Chao Chen  (陈超), Man Xing  (邢曼) & Yue-lai Chen  (陈跃来)

  2. People’s Hospital of Xinjiang Autonomous Region, Urumqi, 830001, P. R. China

    Li-fu Ha  (哈力甫)

  3. Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, P. R. China

    Jian-hua Zhao  (赵建华)

Authors
  1. Qi-fan Feng  (冯琦钒)
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  2. Yu-lin Fu  (傅御麟)
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  3. Chao Chen  (陈超)
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  4. Man Xing  (邢曼)
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  5. Li-fu Ha  (哈力甫)
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  6. Jian-hua Zhao  (赵建华)
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  7. Yue-lai Chen  (陈跃来)
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Corresponding author

Correspondence to Yue-lai Chen  (陈跃来).

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Feng, Qf., Fu, Yl., Chen, C. et al. Quantity-effect relationship of electroacupuncture for urge incontinence: A multicenter randomized controlled trial. J. Acupunct. Tuina. Sci. 10, 49–53 (2012). https://doi.org/10.1007/s11726-012-0569-x

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  • DOI: https://doi.org/10.1007/s11726-012-0569-x

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