摘要
目的
观察头皮针治疗脑梗死康复期认知障碍前后事件相关电位P300 的变化, 并评价其疗效。
方法
66 例年龄在70 岁以下首次发病的脑梗死患者, 处于疾病康复期, 存在认知障碍, 随机分为两组, 即治疗组和对照组。 两组均予神经内科常规药物治疗及康复科常规统一运动康复训练, 治疗组加用头皮针治疗。 治疗前及治疗3 个月后, 两组均采用事件相关电位P300 测定潜伏期和波幅, 比较两组治疗前后的变化。
结果
治疗组治疗后P300 潜伏期平均缩短39.1 ms, 对照组平均缩短16.7 ms, 两组P300 潜伏期均有一定程度的改善。但治疗组改善幅度优于对照组, 差异有统计学意义(P<0.05)。
结论
事件相关电位 P300 能客观评价头皮针治疗脑梗死康复期认知障碍患者认知功能的疗效, 头皮针对促进康复期脑梗死患者认知障碍的恢复有积极作用。
Abstract
Objective
To observe the event related potential 300 (P300) after scalp acupuncture treatment in patients with cognitive disorder due to cerebral infarction, and evaluate its therapeutic effect.
Methods
Sixty-six patients aged below 70 years old with cognitive disorder after initial onset of cerebral infarction were randomized into a treatment group and a control group. Conventional neurological drugs and physical trainings were prescribed to both groups. In addition, the treatment group received scalp acupuncture. The two groups were compared by evaluating the latency and amplitude of P300 before and after the 3-month treatment.
Results
After treatment, the latency of P300 was shortened by 39.1 ms in the treatment group, versus 16.7 ms in the control group, and the difference was statistically significant (P<0.05).
Conclusion
P300 can objectively evaluate the therapeutic effect of scalp acupuncture in treating the patients with cognitive disorder due to cerebral infarction. Scalp acupuncture has positive effect in treating this group of patients.
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Xie, Dl., Zhu, Lf., Liu, Hy. et al. Application of P300 in scalp acupuncture for cognitive disorder due to cerebral infarction. J. Acupunct. Tuina. Sci. 10, 26–28 (2012). https://doi.org/10.1007/s11726-012-0564-2
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DOI: https://doi.org/10.1007/s11726-012-0564-2