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Traitement médical de la diverticulite sigmoïdienne

Medical treatment of sigmoid diverticulitis

  • Dossier Thématique / Thematic File
  • Published:
Côlon & Rectum

Résumé

La diverticulose colique est une affection fréquente dans les pays industrialisés dont la prévalence augmente avec l’âge. La diverticulite correspond à une inflammation et à la survenue d’une infection au niveau du diverticule et de la région péridiverticulaire. La prise en charge médicale d’un patient atteint de diverticulite peut être ambulatoire, mais l’hospitalisation est nécessaire en cas d’intolérance alimentaire, de poussée sévère, en cas de complications décelées sur la tomodensitométrie ou en l’absence de réponse au traitement ambulatoire. Le traitement médical est essentiellement basé sur une antibiothérapie à large spectre, couvrant à la fois les flores aérobies et anaérobies, pour une durée de sept à dix jours qui peut être adaptée selon l’évolution. L’absence d’amélioration des signes infectieux en moins de trois jours doit conduire à rechercher, par tomodensitométrie, une complication qui peut nécessiter un geste invasif tel qu’un drainage percutané ou la chirurgie. Les données de la littérature ne permettent de recommander ni de régime alimentaire, ni de traitement médicamenteux, en prévention d’une première poussée ou d’une récidive de diverticulite chez un patient ayant une diverticulose colique.

Abstract

Diverticulosis is a common colonic disease in industrialized societies and its prevalence increases with age. Acute diverticulitis is defined by diverticular and peridiverticular inflammation and infection. For most patients, outpatient therapy is possible and hospitalization is only indicated if the patient is unable to eat, suffers from an acute attack, has complications or if symptoms fail to improve despite adequate outpatient therapy. The treatment of acute uncomplicated diverticulitis usually consists of broad-spectrum antibiotics covering both aerobic and anaerobic bacteria. Antimicrobial therapy is given for 7 to 10 days but the duration of the treatment can be longer if there are complications. If there is no clinical improvement within 2 or 3 days, repeat CT imaging is appropriate, as this may reveal an abscess, phlegmon or fistula, which might necessitate percutaneous drainage or surgery. The published literature does not support the recommendation of any prophylactic diet or medical treatment for reducing the risk of first or recurrent diverticulitis in patients with diverticulosis.

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Références

  1. Jun S, Stollman N (2002) Epidemiology of diverticular disease. Best Pract Res Clin Gastroenterol 16:529–542

    Article  PubMed  Google Scholar 

  2. Ludeman L, Warren BF, Sheperd NA (2002) The pathology of diverticular disease. Best Pract Res Clin Gastroenterol 16:543–562

    Article  PubMed  Google Scholar 

  3. Acosta JA, Grebenc ML, Doberneck RC, et al (1992) Colonic diverticular disease in patients of 40 years old or younger. Am Surg 58:605–607

    PubMed  CAS  Google Scholar 

  4. Kircher MF, Rhea JT, Kihiczak D, Novelline RA (2002) Frequency, sensitivity and specificity of individuals signs of diverticulitis on thin-section helical CT with colonic contrast material: experience with 312 cases. Am J Roentgenol 178:1313–1318

    Google Scholar 

  5. Stollman N, Raskin JB (2004) Diverticular disease of the colon. Lancet 363:631–639

    Article  PubMed  Google Scholar 

  6. Buchanan GN, Kenefick NJ, Cohen CR (2002) Diverticulitis. Best Pract Res Clin Gastroenterol 16:635–647

    Article  PubMed  Google Scholar 

  7. Tursi A (2004) Acute diverticulitis of the colon: current medical therapeutic management. Expert Opin Pharmacother 5:55–59

    Article  PubMed  CAS  Google Scholar 

  8. Brook I, Frazier EH (2000) Aerobic and anaerobic microbiology in intra-abdominal infections associated with diverticulitis. J Med Microbiol 49:827–830

    PubMed  CAS  Google Scholar 

  9. Kellum JM, Sugerman HJ, Coppa GF, et al (1992) Randomized, prospective comparison of cefoxitin and gentamicin-clindamycin in the treatment of acute colonic diverticulitis. Clin Ther 14:376–384

    PubMed  CAS  Google Scholar 

  10. Société de pathologie infectieuse de langue française (2002) Comment améliorer la qualité de l’antibiothérapie dans les établissements de soins ? Med Mal Infect 32:320–328

    Article  Google Scholar 

  11. Jacobs DO (2007) Diverticulitis. N Engl J Med 357:2057–2066

    Article  PubMed  CAS  Google Scholar 

  12. Ornstein MH, Littlewood ER, McLain Baird I, et al (1981) Are fibre supplements really necessary in diverticular disease of the colon? A controlled clinical trial. Br Med J 282:1353–1356

    Article  CAS  Google Scholar 

  13. Papi C, Capurso L (2005) Management of diverticular disease: is there a room for rifaximin? In: Rifaximin: a poorly absorbed antibiotic. Pharmacology and clinical use. Basel, Karger 196–204

  14. Janes S, Meagher A, Frizellz FA (2005) Elective surgery after acute diverticulitis. Br J Surg 92:133–142

    Article  PubMed  CAS  Google Scholar 

  15. Tursi A, Brandimarte G, Daffina R (2002) Long-term treatment with mesalazine and rifaximin versus rifaximin alone for patients with recurrent attacks of acute diverticulitis of colon. Digest Liver Dis 34:510–515

    Article  CAS  Google Scholar 

  16. Dughera L, Serra AM, Battaglia E, et al (2004) Acute recurrent diverticulitis is prevented by oral administration of a polybacterial lysate suspension. Minerva Gastroenterol Dietol 50:149–153

    PubMed  CAS  Google Scholar 

  17. Myllykangas-Luosujarvi R (1995) Diverticulosis: a primary cause of life-threatening complications in rheumatoid arthritis. Clin Exp Rheumatol 13: 79–82

    PubMed  CAS  Google Scholar 

  18. Mpofu S, Mpofu CMA, Hutchinson D, et al (2004) Steroids, nonsteroidal anti-inflammatory drugs, and sigmoid diverticular abscess perforation in rheumatic conditions. Ann Rheum Dis 63:588–590

    Article  PubMed  CAS  Google Scholar 

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Correspondence to J. L. Dupas.

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Dupas, J.L. Traitement médical de la diverticulite sigmoïdienne. Colon Rectum 3, 16–19 (2009). https://doi.org/10.1007/s11725-009-0137-9

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  • DOI: https://doi.org/10.1007/s11725-009-0137-9

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