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Hormones sexuelles et mécanismes endogènes de modulation de la douleur

Sex hormones and endogenous pain modulation mechanisms

  • Revue de la Littérature / Literature Review
  • Published:
Douleur et Analgésie

Résumé

Les hommes et les femmes vivent différemment l’expérience douloureuse, et plusieurs facteurs peuvent expliquer ce phénomène. Les hormones sexuelles sont de bonnes candidates pour expliquer, du moins en partie, ces différences entre les sexes. En effet, ces molécules sont aptes à moduler les mécanismes facilitateurs et inhibiteurs de la douleur. Cette revue de la littérature fera donc un tour d’horizon en ce qui a trait à l’effet des hormones sexuelles sur ces mécanismes et plus spécifiquement au niveau de l’inhibition de la douleur.

Abstract

Men and women experienced pain differently and several factors may explain this phenomenon. Sex hormones are good candidates to explain, at least in part, these sex differences. Indeed, these molecules are able to modulate pain facilitatory and inhibitory mechanisms. This review of literature will therefore present an overview of the effect of sex hormones on these mechanisms, and more specifically in pain inhibition.

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Gaumond, I. Hormones sexuelles et mécanismes endogènes de modulation de la douleur. Douleur analg 22, 146–151 (2009). https://doi.org/10.1007/s11724-009-0136-5

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  • DOI: https://doi.org/10.1007/s11724-009-0136-5

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