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Synthesis and thermal stability of selenium-doped hydroxyapatite with different substitutions

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Abstract

Selenium (Se) plays a specific role in human health, especially for its antitumor effect. Incorporation of selenium into biocompatible hydroxyapatite (HAP) may endow the materials with novel characteristics. In the current work, a series of seleniumdoped hydroxyapatite (Se-HAP) nanoparticles with different Se/P ratios were synthesized by a modified chemical precipitation. It was revealed that the powders with/without heattreatment were nano-sized needle-like HAP while the heat-treated samples have high crystallinity. The addition of selenium decreases the crystallinity of the synthesized apatite, and also takes a negative effect on the thermal stability of the as-prepared powders. The Se-HAP nanoparticles with Se/P molar ratio not more than 5% sintered at 900°C can achieve good crystallinity and thermal stability.

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Authors and Affiliations

  1. Advanced Biomaterials and Tissue Engineering Center, Huazhong University of Science and Technology, Wuhan, 430074, China

    Yonghui Liu, Jun Ma & Shengmin Zhang

  2. Department of Biomedical Engineering, Huazhong University of Science and Technology, Wuhan, 430074, China

    Jun Ma & Shengmin Zhang

Authors
  1. Yonghui Liu
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  2. Jun Ma
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  3. Shengmin Zhang
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Correspondence to Shengmin Zhang.

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Liu, Y., Ma, J. & Zhang, S. Synthesis and thermal stability of selenium-doped hydroxyapatite with different substitutions. Front. Mater. Sci. 9, 392–396 (2015). https://doi.org/10.1007/s11706-015-0313-9

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  • DOI: https://doi.org/10.1007/s11706-015-0313-9

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