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Preparation and application of highly porous aerogel-based bioactive materials in dentistry


In this study, the possibility of preparation and application of highly porous silica aerogel-based bioactive materials are presented. The aerogel was combined with hydroxyapatite and β-tricalcium phosphate as bioactive and osteoinductive agents. The porosity of aerogels was in the mesoporous region with a maximum pore diameter of 7.4 and 12.7 nm for the composite materials. The newly developed bioactive materials were characterized by scanning electron microscopy. The in vitro biological effect of these modified surfaces was also tested on SAOS-2 osteogenic sarcoma cells by confocal laser scanning microscopy.

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Correspondence to Csaba Hegedüs.

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Kuttor, A., Szalóki, M., Rente, T. et al. Preparation and application of highly porous aerogel-based bioactive materials in dentistry. Front. Mater. Sci. 8, 46–52 (2014).

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  • aerogel
  • sol-gel technique
  • bioactive material
  • SAOS-2 cell