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Microwave-assisted synthesis and antimicrobial activities of 2-aryl-3-(naphthalene-1 or 2-yl)-1,3-thiazolidin-4-ones

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Abstract

2-aryl-3-(naphthalene-1 or 2-yl)-1, 3-thiazolidin-4-ones 4 and 5 were synthesized in 41%–67% yield by using microwave-assisted one-pot protocol. The structures of the new compounds 4l, 4m, 5c, 5e, 5g, 5h, and 5j–5m were confirmed by IR, NMR, MS, and elemental analysis. The antimicrobial activities of the compounds against Pseudomonas syringae pv. lachrymans (Smith et Bryan) Young, Dye & Wilkie, Botrytis cinerea Pers., and Sphaerotheca fusca Blum. were examined. Some of the compounds showed good antifungical activity against Sphaerotheca fusca Blum.

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Authors and Affiliations

  1. Key Laboratory of Chemical Biology of Hebei Province, College of Chemistry and Environmental Science, Hebei University, Baoding, 071002, China

    Hua Chen, Yanan Li, Jie Bai, Lian Zhao, Xiangguo Yuan & Xiaoliu Li

  2. Key Laboratory of Medicinal Chemistry and Molecular Diagnosis, Ministry of Education, Hebei University, Baoding, 071002, China

    Xiaoliu Li

  3. College of Plant Protection, Hebei Agricultural University, Baoding, 071001, China

    Keqiang Cao

Authors
  1. Hua Chen
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  2. Yanan Li
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  3. Jie Bai
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  4. Lian Zhao
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  5. Xiangguo Yuan
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  6. Xiaoliu Li
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  7. Keqiang Cao
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Correspondence to Hua Chen or Xiaoliu Li.

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Chen, H., Li, Y., Bai, J. et al. Microwave-assisted synthesis and antimicrobial activities of 2-aryl-3-(naphthalene-1 or 2-yl)-1,3-thiazolidin-4-ones. Front. Chem. Eng. China 3, 186–191 (2009). https://doi.org/10.1007/s11705-009-0004-0

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