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Effects of aflatoxin-detoxifizyme on growth performance and liver biochemical indices of broilers fed with aflatoxin B1

  • Research Article
  • Published:
Frontiers of Agriculture in China

Abstract

Aflatoxin-detoxifizyme (ADTZ) was evaluated for its ability to reduce the deleterious effects of aflatoxin B1 (AFB1) in broiler diets. A total of 624 one-day-old AA broilers were randomly divided into 3 treatment groups with 8 replicates each. The control, AFB1 and ADTZ treatments were fed with basal diet, basal diet + 0.1 mg/kg AFB1 and basal diet + 0.1 mg/kg AFB1 + 0.3% ADTZ, respectively. The trials lasted 42 days. The results showed that: (1) AFB1 diminished the growth performance of broilers significantly (P < 0.01). (2) The AFB1 supplement caused significant alteration of related liver enzyme activities and significantly decreased the body’s antioxidant capacity. (3) Related parameters were returned to normal levels by a 0.3% ADTZ addition to the AFB1-contaminated diet. All the results in the trials indicate that ADTZ has the ability to detoxify AFB1 and recover the negative effects of AFB1.

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References

  • Chen F, Lu Y H, Wang X H (2008). Study on non-selectional adsorption of vitamins by mycotoxin adsorbent. Chinese Journal of Animal Science, 44(18): 8–10 (in Chinese)

    CAS  Google Scholar 

  • Hou R R, Xie P, Zhang M H, Feng J H, Zheng S S, Ma A P (2008b). Effects of glucomannan on liver biochemical indices and hepatic pathological observation of broilers fed with dietary containing aflatoxin B1. Chinese Journal of Animal Nutrition, 20(2): 152–157 (in Chinese)

    CAS  Google Scholar 

  • Hou R R, Zheng S S, Zhang M H, Feng J H, Ma A P, Xie P (2008a). Effects of glucomannan on growth performance, serum and organ indices of broilers fed with dietary containing aflatoxin B1. Chinese Journal of Animal Nutrition, 20(2): 146–151 (in chinese)

    CAS  Google Scholar 

  • Lindemann M D, Blodgett D J, Kornegay E T, Schurig G G (1993). Potential ameliorators of aflatoxicosis in weanling/growing swine. J Anim Sci, 71(1): 171–178

    PubMed  CAS  Google Scholar 

  • Long X K, Tang R G, Hang H Q (2007). Analysis of detection level of serum lipid and cholinesterase in patients with liver cancer. Journal of Practical Medical Techiques, 14(12): 1574–1575 (in Chinese)

    Google Scholar 

  • Quezada T, Cuellar H, Jaramillo-Juarez F, Valdivia A G, Reyes J L (2000). Effect of aflatoxin B1 on the liver and kidney of broiler chickens during development. Comp Biochem Physiol, 125(Part C): 265–272

    CAS  Google Scholar 

  • Richard L (1989). Microbial toxins in foods and feeds. Symposium on Cellular and Molecular Mode of Action of Selected Microbial Toxins in Foods and Feeds. New York: Plenum Press, 1990

    Google Scholar 

  • Shi Y H, Xu Z R, Wang C Z (2007). Effects of aflatoxin on growth performance and immunology and antioxidant indices in pigs. Chin J Vet Sci, 27(5): 733–736 (in Chinese)

    CAS  Google Scholar 

  • Verma J, Swain B K, Johri T S (2002). Effect of various levels of aflatoxin and ochratoxin A and combinations thereof on protein and energy utilisation in broilers. J Sci Food Agric, 82(12): 1412–1417

    Article  CAS  Google Scholar 

  • Wills E D (1966). Mechanism of lipid peroxide formation in animal tissues. J Biochem, 99: 667–676

    CAS  Google Scholar 

  • Wilson R W, Bergman H L, Wood C M (1994). Metabolic costs and physiological consequences of acclimation to aluminum in juvenile rainbow trout (Oncorhynchus mykiss). II. Gill morphology, swimming performance, and aerobic scope. Can J Fish Aquat Sci, 51: 536–544

    Article  CAS  Google Scholar 

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Correspondence to Baojiang Chen.

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Chen, B., Wang, Y., Yu, H. et al. Effects of aflatoxin-detoxifizyme on growth performance and liver biochemical indices of broilers fed with aflatoxin B1 . Front. Agric. China 5, 594–597 (2011). https://doi.org/10.1007/s11703-011-1135-x

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  • DOI: https://doi.org/10.1007/s11703-011-1135-x

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