Abstract
Intramolecular oxa-6π-electrocyclization reaction are described for 3-allylideneindolin-2-one derivatives in the presence of easily prepared B(HSO4)3 catalyst and their conversion to 2,9-dihydropyrano[2,3-b]-indoles in up to 72% yield under mild condition. 3-allylideneindolin-2-one has been obtained from the reaction of isatin and 1,3-dichloropropene. Comfortable synthetic conversions of the products readily lead to pharmacologically interesting numerous functional groups.
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Acknowledgements
We wish to express our gratitude to the research council of Islamic Azad University, Science and Research Branch Tehran, Iran.
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This study was funded by the research council of Islamic Azad University, Science and Research Branch Tehran, Iran national elites’ foundation.
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Abbasi Varnakesh, P., Azizian, J. Synthesis of 2,9-dihydropyrano[2,3-b]-indoles via intramolecular oxa-6π-electrocyclization reaction from synthesized 3-allylideneindolin-2-one intermediates. Chem. Pap. (2024). https://doi.org/10.1007/s11696-024-03427-0
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DOI: https://doi.org/10.1007/s11696-024-03427-0