Abstract
The importance of probiotics for the internal and external human microbiota has already been scientifically confirmed. As these are viable bacteria, the direct dermal use of them through mass-produced cosmetics is impossible. For these purposes, postbiotics—substances derived from probiotics through fermentation processes—appear to be promising. Two postbiotics have been investigated in vitro for their protective ability against free radicals and UV radiation compared to conventional synthetic chemicals. Lactococcus Ferment Lysate and Bifida Ferment Lysate in 5% aqueous solution and 100% concentrate were able to scavenge from 0.15 to 54.2% and 7.0 to 71.0%, respectively, of 2,2-diphenyl-1-picrylhydrazyl radical. L. Ferment Lysate in the emulsion, the composition of which is a reference in testing the effectiveness of sunscreen products with a low SPF value, showed an absorption capacity in the UVB region (SPF 4.75) comparable to the standard chemical UV filter Homomenthyl salicylate (SPF value of 4.45) and in the UVA region better than this standard. The UV absorption ability of B. Ferment Lysate was negligible. Postbiotics B. Ferment Lysate and L. Ferment Lysate are beneficial natural active ingredients for the skin protection against free radicals and L. Ferment Lysate also against UVB + UVA radiation.
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Acknowledgements
The study was financially supported by the Grant VEGA 2/0136/20 and Grant APVV-16-0088.
Funding
Funding was provided by agentúra ministerstva školstva,vedy,výskumu a športu sr (2/0136/20) and agentúra na podporu výskumu a vývoja (16-0088).
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Ácsová, A., Hojerová, J. & Martiniaková, S. Efficacy of postbiotics against free radicals and UV radiation. Chem. Pap. 76, 2357–2364 (2022). https://doi.org/10.1007/s11696-021-02018-7
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DOI: https://doi.org/10.1007/s11696-021-02018-7