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Synthesis, spectrophotometric, spectroscopic, microbial studies and analytical applications of Cu(II) and Zn(II) complexes of chalcone ligand

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Abstract

The ligation behavior of the chalcone ligand namely (E)-3-(4-hydroxy-3-methoxyphenyl) acrylic acid (ferulic acid) (FA) toward the Cu(II) and Zn(II) ions was determined. The structure of the isolated solid complexes was elucidated by elemental analyses, spectral techniques (IR, UV–Vis, 13C– and 1H-NMR spectra) as well as the conductance measurements and thermal analyses. UV–Vis spectra and magnetic moments had suggested square planar and tetrahedral stereochemistry for Cu(II) and Zn(II) complexes, respectively. The kinetic and thermodynamic parameters for some selected decomposition steps have been calculated. Two precise and sensitive spectrophotometric methods were utilized to determine Zn(II) and Cu(II) complexes with ferulic acid using a micellar media of cetylpyridinium bromide (CPB) and sodium lauryl sulfate (SLS) with an absorption maxima of 430 and 465 nm for Zn(II) and Cu(II), respectively. Various analytical conditions, for example, the concentration of the reagent, temperature, the sequence and timing of addition were also looked into. Under optimum conditions, the complexes exhibited good linearity in concentration range of 2.0–70.0 and 4.0–140.0 µg mL−1; molar absorptivities 1.3161 × 104 and 8.826 × 103 L mol−1 cm−1; and Sandell’s sensitivity 0.00496 and 0.00719 µg cm−2 for the proposed methods of Zn(II) and Cu(II), respectively. The complexes ratio was found to be 1:2 [Zn(II):FA or Cu(II):FA] and the stability constants were 2.771 × 105 and 2.826 × 105, respectively. Finally, the newly synthesized complexes were shown potent antimicrobial activity.

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The datasets used and/or analyzed during the current study available from the corresponding author on reasonable request.

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Acknowledgements

The authors extend their appreciation to Zagazig University and University of Bisha.

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Authors and Affiliations

  1. Faculty of Science, Chemistry Department, Zagazig University, Zagazig, 44519, Egypt

    Badr Abd El-wahaab, Wesam S. Shehab & Walaa H. El-Shwiniy

  2. Department of Chemistry, College of Science, University of Bisha, Bisha, 61922, Saudi Arabia

    Walaa H. El-Shwiniy

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  1. Badr Abd El-wahaab
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  3. Walaa H. El-Shwiniy
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Contributions

BAE contributed to conceptualization and funding acquisition; BAE and WSS contributed to investigation; WSS contributed to methodology; BAE, WSS and WHE contributed to project administration, resources, software, and supervision; WHE contributed to validation and visualization; BAE, WHE and WSS contributed to writing—original draft and writing—review and editing.

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Correspondence to Badr Abd El-wahaab.

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Abd El-wahaab, B., Shehab, W.S. & El-Shwiniy, W.H. Synthesis, spectrophotometric, spectroscopic, microbial studies and analytical applications of Cu(II) and Zn(II) complexes of chalcone ligand. Chem. Pap. 76, 931–944 (2022). https://doi.org/10.1007/s11696-021-01916-0

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