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Synthesis and characterization of new secondary benzylamines derivatives of aryl-himachalene

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A simple and efficient synthesis of aryl-himachalene benzylamines derivatives from himachalenes, natural sesquiterpenes isolated from essential oil of Cedrus atlantica, via chloromethylation reaction. Various aromatic amines were used to provide the corresponding secondary benzylamines in good yields. The reaction offers a first practical synthetic method for the preparation of a range of sesquiterpenes with benzylamines moiety.

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Correspondence to Brahim Boualy.

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Ait Lahcen, I., Edder, Y., Mallouk, S. et al. Synthesis and characterization of new secondary benzylamines derivatives of aryl-himachalene. Chem. Pap. 75, 3207–3213 (2021).

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