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Quinoxaline-based chromogenic and fluorogenic chemosensors for the detection of metal cations

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The development of molecular and supramolecular optical devices for sensing ionic analytes in solution has emerged as a promissory field in the last decades. In this context, qualitative and quantitative analysis of metal cations based on chromogenic and fluorogenic chemosensors are particularly attractive, especially due to their successfully employment for biological and environmental purposes. In this work, the literature data associated to quinoxaline-based derivatives as chemosensors for metal cations in solution are comprehensively reviewed. Sensing mechanisms, detection limits, solvent effect, work concentration ranges, as well as examples of practical implementation are presented. We believe that the data compilation and pertinent discussion present in this survey should be of interest for researchers of heterocyclic-based chemosensors’ field.

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Adapted from reference (Mako et al. 2019)

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The authors would like to acknowledge the following Brazilian entities for financial support: Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES, Finance code 001), Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), Financiadora de Estudos e projetos (FINEP), and Fundação de Apoio à Pesquisa do EN (FAPERN).

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Correspondence to Fabrício G. Menezes.

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da Silva, L.C., Machado, V.G. & Menezes, F.G. Quinoxaline-based chromogenic and fluorogenic chemosensors for the detection of metal cations. Chem. Pap. 75, 1775–1793 (2021).

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