Skip to main content
Log in

Synthesis, radical scavenging, and antimicrobial activities of core–shell Au/Ni microtubes

  • Original Paper
  • Published:
Chemical Papers Aims and scope Submit manuscript


Highly ordered Ni/Au core–shell microtube (MT) arrays with the inner diameters of 110 ± 13 nm and the wall thickness of 118 ± 5 nm were synthesized by a two-step template deposition approach in pores of the track-etched membranes. First, the Au MTs were obtained by electroless plating. On the second stage, Ni MTs were electrochemically deposited inside gold MTs. The dimensions, chemical composition, and crystal structure of the synthesized samples have been analyzed using scanning electron microscopy, energy dispersive analysis as well as X-ray diffraction technique. The in vitro antioxidant activity of synthesized single component and core–shell MTs was evaluated by scavenging of 2.2-diphenyl-1-picrylhydrazyl hydrate (DPPH) radical and the effective rate of inhibition IC50 for DPPH radical was found to be 0.49 for Au/Ni MTs and 3.22 and 2.73 for Ni and Au MTs, respectively. The antibacterial activity was elucidated against the strains such as: Staphylococcus aureus, Bacillus subtilis, Escherichia coli and the yeast-like fungus Candida albicans P. by the agar diffusion method. The core–shell Au/Ni MTs possess the highest activity against the tested Gram-negative bacteria E. Coli (zone of inhibition of 37 ± 1.0 mm). Gram-positive bacteria S. Aureus showed resistance to the Au/Ni MTs; however, single component of Au and Ni MTs showed a pronounced antimicrobial activity as compared to Penicillin G sodium (control).

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others


Download references

Author information

Authors and Affiliations



Conceptualization, A.M. and A.K.; data duration, M.I and Zh.A.; formal analysis, A.M. and M.K..; funding acquisition, M.Z.; investigation, M.I., S.A. and A.K.; methodology, A.M. and M.Z.; supervision, A.B.; writing-original draft, A.M. and A.K.; writing-review and editing, A.M.

Corresponding author

Correspondence to Anastassiya A. Mashentseva.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Mashentseva, A.A., Ibragimova, M.A., Akhmetova, S.B. et al. Synthesis, radical scavenging, and antimicrobial activities of core–shell Au/Ni microtubes. Chem. Pap. 74, 2189–2199 (2020).

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: