N-Unsubstituted cyclic imides were readily synthesized in deep eutectic solvent (DES) choline chloride (ChCl)/urea from anhydrides with urea. Urea serves as both a DES component and a nitrogen source, which endows the protocol with advantages of smooth reaction, easy separation of products, simple recovery and recycling of ChCl/urea.
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Liu, L., Zhang, HY., Yin, G. et al. Synthesis of N-unsubstituted cyclic imides from anhydride with urea in deep eutectic solvent (DES) choline chloride/urea. Chem. Pap. 74, 1351–1357 (2020). https://doi.org/10.1007/s11696-019-00969-6
- N-Unsubstituted cyclic imides
- Deep eutectic solvent
- Choline chloride/urea