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Incidence and Intensity of Early Dumping Syndrome and Its Association with Health-Related Quality of Life Following Sleeve Gastrectomy

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Abstract

Background and Purpose

Dumping syndrome (DS) is a shared but underappreciated complication after metabolic-bariatric surgery. The purpose of the study was to investigate the prevalence and intensity of symptoms suggestive of DS and their relationship with health-related quality of life (HRQOL) after laparoscopic sleeve gastrectomy (LSG).

Method

A retrospective cohort study was performed for all patients with a history of sleeve gastrectomy between July 2017 and July 2022 in our center. Basial clinic statistics were gathered from electronic medical database, the prevalence and severity of DS were assessed by Dumping Symptom Rating Scale (DSRS), and HRQOL is collected through the Short Form Health Survey 36 (SF-36).

Result

In total, 133 of 202 patients completed the questionnaire (response rate 65.8%). A total of 64.7% (N = 86) of participants were female, aged 34.0 (IQR 26.0–39.0) years at completion of the questionnaire, with a mean body mass index of 35.8 (IQR 31.4–40.5) kg/m2. The prevalence of symptoms suggestive of DS was 45.9% (N = 61), and the associated protective factor was the time between surgery and study. Compared with the patients without DS, patients with DS scored significantly worse on four of eight SF-36 subdomains.

Conclusion

Symptoms suggestive of early dumping syndrome after sleeve gastrectomy are common and are associated with a worse health-related quality of life, which deserves clinical attention. Additional counselling, education, and care are needed to mitigate the decline in quality of life caused by dumping symptoms.

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Authors and Affiliations

  1. Division of Gastrointestinal Surgery, Department of General Surgery, West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu, 610041, China

    Jun-Cheng Yang, Gui-Xiang Zhang, Cuo Leng, Gang Chen, Zhong Cheng & Xiao Du

  2. Department of General Surgery, The Second Clinical Medical College, The Fifth People’s Hospital Affiliated to Chengdu University of Traditional Chinese Medicine, Chengdu, 610041, China

    Gang Chen

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  1. Jun-Cheng Yang
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  4. Gang Chen
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Corresponding author

Correspondence to Xiao Du.

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Ethical Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Key Points

Dumping syndrome after sleeve gastrectomy is very common.

Dumping syndrome is associated with a worse healthrelated quality of life.

Counselling, education, and care are needed for dumping syndrome after bariatric surgery.

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Yang, JC., Zhang, GX., Leng, C. et al. Incidence and Intensity of Early Dumping Syndrome and Its Association with Health-Related Quality of Life Following Sleeve Gastrectomy. OBES SURG 33, 3510–3516 (2023). https://doi.org/10.1007/s11695-023-06863-1

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  • DOI: https://doi.org/10.1007/s11695-023-06863-1

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