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Helicobacter pylori Increases Gastric Compliance on Resected Stomach After Laparoscopic Sleeve Gastrectomy

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Abstract

Background

The relationship between high body mass index (BMI) and Helicobacter pylori (HP) was reported previously. But the mechanism is not clear. We aimed to evaluate the effect of HP on gastric compliance and volumes in obese patients.

Materials and Methods

One hundred fifty-nine patients who underwent sleeve gastrectomy due to morbid obesity were enrolled in the study and were divided into two groups as HP+ (n = 86) and HP− (n = 73) according to the HP status in resection materials. Demographics, pathological data, specimen sizes, volume, and compliance were retrospectively analyzed.

Results

The median age of the study group was 34 years (17–64 years) while the median BMI was 43 kg/m2 (35–64, 3 kg/m2). Most of the patients (n = 134, 84.3%) were female. The median diameter of the widest point of the specimen was 22.5 cm (14–32 cm), and the median volume of the specimen was 790 cc (330–1920 cc). Both the diameter of the widest point and the volume of the specimens were significantly increased in the HP+ group compared to the HP− group (p < 0.001 and p = 0.017, respectively). In addition, the median compliance was 52.6 cc/mmHg, and the compliance was significantly higher (p < 0.001) in the HP+ group. There were no significant differences in specimen sizes between the two groups.

Conclusion

This is the first study showing that HP increases gastric compliance in obese patients who underwent LSG. The etiology and the effects of this increase in compliance have not been fully clarified yet. Further studies are needed to shed light on these effects.

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Authors and Affiliations

  1. Department of Gastrointestinal Surgery, Inonu University, Malatya, Turkey

    Kuntay Kaplan, Emre Turgut & Gokalp Okut

  2. Department of Gastrointestinal Surgery, Inonu University, Malatya, Turkey

    Emre Turgut

  3. Department of Gastrointestinal Surgery, Health Sciences University Van Training and Research Hospital, Van, Turkey

    Yusuf Murat Bag

  4. Department of Gastrointestinal Surgery, Irmet Hospital International, Çerkezköy, Turkey

    Fatih Sumer

  5. Department of Gastrointestinal Surgery, Yeditepe University, Istanbul, Turkey

    Cuneyt Kayaalp

Authors
  1. Kuntay Kaplan
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  2. Emre Turgut
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  3. Gokalp Okut
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  4. Yusuf Murat Bag
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  5. Fatih Sumer
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  6. Cuneyt Kayaalp
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Contributions

All of the authors declare that they have all participated in the design, execution, and analysis of the paper, and that they have approved the final version.

Corresponding author

Correspondence to Emre Turgut.

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Ethics Approval

This study was approved by the Inonu University Health Sciences Non-Interventional Clinical Research Ethics Committee with the decision numbered 2021/1596. All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Informed Consent Statement

Informed consent was obtained from all individual participants included in the study.

Conflict of Interest

The authors declare no competing interests.

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Key Points

1. Helicobacter pylori increases gastric compliance.

2. Increased gastric compliance may be associated with obesity but needs further studies.

3. There was no significant difference between HP+ and HP− patients in terms of postoperative complications.

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Kaplan, K., Turgut, E., Okut, G. et al. Helicobacter pylori Increases Gastric Compliance on Resected Stomach After Laparoscopic Sleeve Gastrectomy. OBES SURG 31, 4776–4780 (2021). https://doi.org/10.1007/s11695-021-05616-2

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