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Laparoscopic Roux-en-Y Gastric Bypass and Laparoscopic Sleeve Gastrectomy in Terms of Efficacy and Safety: a Comparative Study During 11-Year Experience

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Abstract

Purpose

This cohort study was designed to compare the efficacy and safety of laparoscopic Roux-en-Y gastric bypass (LRYGB) and laparoscopic sleeve gastrectomy (LSG) for the management of morbid obesity during the 11-year experience.

Materials and Methods

This study was conducted between July 2006 and August 2019. Annually we recorded data about the weight, body mass index (BMI), percentage of excess weight loss (%EWL), percentage of weight loss (%WL), weight regain, and postoperative complications into a prospectively collected database.

Results

A total of 1146 patients (LRYGB=396 and LSG=750) aged >18 years old were included in the study. Over the first 7 years after surgery, the weight loss rate was significantly higher in the LRYGB-treated group than the LSG-treated group, and weight regain was significantly lower in the LRYGB-treated group in comparison with the LSG-treated group. Our results revealed that statistically, but not clinically, the efficacy of LRYGB and LSG is equivalent in terms of %WL, %EWL, and weight regain within 8 years and more. Besides, there were no significant differences in surgery-related mortality and severe complications between the two procedures.

Conclusion

Our study’s results indicated that the clinical efficacy of LRYGB in the management of obesity is better than LSG during the 11-year experience. But the differences in weight loss and weight regain were not statistically relevant at 8 years and more after the surgery. Also, a comparison of severe complications did not indicate significant differences between the two groups.

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Author information

Authors and Affiliations

  1. Department of Surgery, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran

    Karamollah Toolabi

  2. Nutrition and Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, No. 42, Arabi St., Yemen St., Chamran Exp, Tehran, Iran

    Mahdieh Golzarand

  3. Department of Clinical Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran

    Mahdieh Golzarand

  4. Department of Social Sciences and Health, Durham University, Durham, UK

    Roya Farid

Authors
  1. Karamollah Toolabi
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  2. Mahdieh Golzarand
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  3. Roya Farid
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Contributions

K.T and M.G conceived and carried out the experiments. M.G analyzed and interpreted data. All authors were involved in writing the paper and had final approval of the submitted and published versions.

Corresponding author

Correspondence to Mahdieh Golzarand.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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The authors declare no competing interest.

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Toolabi, K., Golzarand, M. & Farid, R. Laparoscopic Roux-en-Y Gastric Bypass and Laparoscopic Sleeve Gastrectomy in Terms of Efficacy and Safety: a Comparative Study During 11-Year Experience. OBES SURG 31, 2489–2496 (2021). https://doi.org/10.1007/s11695-021-05313-0

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  • DOI: https://doi.org/10.1007/s11695-021-05313-0

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