Bariatric Surgery for Cowden Syndrome with PTEN Mutation: a Case Report

This is a preview of subscription content, access via your institution.

Fig. 1
Fig. 2
Fig. 3

References

  1. 1.

    Racette SB, Deusinger SS, Deusinger RH. Obesity: overview of prevalence, etiology, and treatment. Phys Ther. 2003;83(3):276–88.

    Article  Google Scholar 

  2. 2.

    Mingrone G, Panunzi S, De Gaetano A, et al. Bariatric–metabolic surgery versus conventional medical treatment in obese patients with type 2 diabetes: 5 year follow-up of an open-label, single-centre, randomised controlled trial. Lancet. 2015;386(9997):964–73.

    Article  Google Scholar 

  3. 3.

    Ranadive SA, Vaisse C. Lessons from extreme human obesity: monogenic disorders. Endocrinol Metab Clin N Am. 2008;37(3):733–51.

    CAS  Article  Google Scholar 

  4. 4.

    Huvenne H, Dubern B, Clement K, et al. Rare genetic forms of obesity: clinical approach and current treatments in 2016. Obes Facts. 2016;9(3):158–73.

    CAS  Article  Google Scholar 

  5. 5.

    Pilarski R, Burt R, Kohlman W, et al. Cowden syndrome and the PTEN hamartoma tumor syndrome: systematic review and revised diagnostic criteria. J Natl Cancer Inst. 2013;105(21):1607–16.

    CAS  Article  Google Scholar 

  6. 6.

    Pal A, Barber TM, Van de Bunt M, et al. PTEN mutations as a cause of constitutive insulin sensitivity and obesity. N Engl J Med. 2012;367(11):1002–11.

    CAS  Article  Google Scholar 

  7. 7.

    Cooiman MI, Kleinendorst L, Aarts EO, et al. Genetic obesity and bariatric surgery outcome in 1014 patients with morbid obesity. Obes Surg. 2019;30(2):470–7.

    Article  Google Scholar 

  8. 8.

    Liu SY, Wong SK, Lam CC, et al. Bariatric surgery for Prader-Willi syndrome was ineffective in producing sustainable weight loss: long term results for up to 10 years. Pediatr Obes. 2020;15(1):e12575.

    Article  Google Scholar 

  9. 9.

    Huang X, Liu G, Guo J, et al. The PI3K/AKT pathway in obesity and type 2 diabetes. Int J Biol Sci. 2018;14(11):1483–96.

    CAS  Article  Google Scholar 

  10. 10.

    Cooiman MI, Kleinendorst L, van der Zwaag B, et al. Genetic analysis in the bariatric clinic; impact of a PTEN gene mutation. Mol Genet Genomic Med. 2019;7(6):e00632.

    Article  Google Scholar 

Download references

Acknowledgements

We would like to thank Editage (www.editage.co.kr) for the English language editing.

Author information

Affiliations

Authors

Corresponding author

Correspondence to Do Joong Park.

Ethics declarations

Ethics Approval and Consent to Participate

This study was conducted in accordance with the Declaration of Helsinki. This study was reviewed and approved by the Institute Review Board of the affiliated hospital (IRB no. 2011-173-1175). Informed consent was obtained from the participant included in the study.

Conflict of Interest

The authors declare no competing interests.

Additional information

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Jang, H.N., Kim, S.H., Cho, Y.M. et al. Bariatric Surgery for Cowden Syndrome with PTEN Mutation: a Case Report. OBES SURG (2021). https://doi.org/10.1007/s11695-021-05231-1

Download citation