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Chronic Abdominal Pain After Previous Bariatric Surgery: Consider the Abdominal Wall

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Abstract

Background

Up to 30% of patients who undergo bariatric surgery experience recurrent abdominal pain within 3 years after the operation. Although some causes for persisting discomfort are well known, a small portion of patients may suffer from an abdominal wall pain associated with Anterior Cutaneous Nerve Entrapment Syndrome (ACNES). Aim of the present study is to discuss incidence, clinical presentation, and treatment outcome in patients with ACNES after bariatric surgery.

Methods

This retrospective observational cohort study analyzed electronically stored data of patients with ACNES having a history of bariatric surgery. All were treated for ACNES between 2011 and 2017 in a Dutch center of excellence for abdominal wall and groin pain. Success after treatment was defined as a minimal 50% drop in pain level using a Numeric Rating Scale.

Results

A total of 49 patients (female n = 44, median age 45 (25–63) years) were identified. Four (8%) experienced long-term pain relief after just one abdominal wall infiltration with lidocaine. Ten additional patients reported success after 2–5 injections. A total of 35 unresponsive patients chose to undergo a neurectomy that was successful in 27. Therefore, this step-up approach conferred an 84% success rate. Occurrence of ACNES after bariatric surgery was estimated at 1 in 100 patients.

Conclusion

ACNES should be considered in the differential diagnosis of ongoing pain following previous bariatric surgery. A treatment regimen including abdominal wall infiltrations using an anesthetic agent or a neurectomy is successful in a vast majority of these patients.

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References

  1. Sjostrom L, Lindroos A, Peltonen M, et al. Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery. N Engl J Med. 2004;351(26):2683–93.

    Article  PubMed  Google Scholar 

  2. Vest AR, Heneghan HM, Agarwal S, et al. Bariatric surgery and cardiovascular outcomes: a systematic review. Heart. 2012;98(24):1763–77.

    Article  PubMed  Google Scholar 

  3. Kushner RF. Weight loss strategies for treatment of obesity. Prog Cardiovasc Dis. 2014;56(4):465–72.

    Article  PubMed  Google Scholar 

  4. Bray GA, Frühbeck G, Ryan DH, et al. Management of obesity. Lancet. 2016;387(10031):1947–56.

    Article  PubMed  Google Scholar 

  5. Benaiges D, Goday A, Pedro-Botet J, et al. Bariatric surgery: to whom and when? Minerva Endocrinol. 2015 Jun;40(2):119.

    CAS  PubMed  Google Scholar 

  6. Cho M, Kaidar-Person O, Szomstein S, et al. Emergency room visits after laparoscopic Roux-en- Y gastric bypass for morbid obesity. Surg Obes Relat Dis. 2008;4(2):104–9.

    Article  PubMed  Google Scholar 

  7. Saunders J, Ballantyne G, Belsley S, et al. One-year readmission rates at a high volume bariatric surgery center: laparoscopic adjustable gastric banding, laparoscopic gastric bypass, and vertical banded gastroplasty-Roux-en-Y gastric bypass. Obes Surg. 2008;18(10):1233–40.

    Article  PubMed  Google Scholar 

  8. Kellogg TA, Swan T, Leslie DA, et al. Patterns of readmission and reoperation within 90 days after Roux-en- Y gastric bypass. Surg Obes Relat Dis. 2009;5(4):416–23.

    Article  PubMed  Google Scholar 

  9. Ukleja A. Dumping syndrome: pathophysiology and treatment. Nutr Clin Pract. 2005;20(5):517–25.

    Article  PubMed  Google Scholar 

  10. Higa K, Boone K, Ho T. Complications of the laparoscopic Roux-en-Y gastric bypass: 1,040 patients - what have we learned? Obes Surg. 2000;10(6):509–13.

    Article  CAS  PubMed  Google Scholar 

  11. Shiffman ML, Sugerman HJ, Kellum JM, et al. Gallstone formation after rapid weight loss: a prospective study in patients undergoing gastric bypass surgery for treatment of morbid obesity. Am J Gastroenterol. 1991;86(8):1000–5.

    CAS  PubMed  Google Scholar 

  12. Sapala J, Wood M, Sapala M, et al. Marginal ulcer after gastric bypass: a prospective 3-year study of 173 patients. Obes Surg. 1998;8(5):505–16.

    Article  CAS  PubMed  Google Scholar 

  13. Dallal RM, Bailey LA. Ulcer disease after gastric bypass surgery. Surg Obes Relat Dis. 2006;2(4):455–9.

    Article  PubMed  Google Scholar 

  14. Schneider BE, Villegas L, Blackburn GL, et al. Laparoscopic gastric bypass surgery: outcomes. J Laparoendosc Adv Surg Tech A. 2003;13(4):247–55.

    Article  PubMed  Google Scholar 

  15. Applegate WV. Abdominal cutaneous nerve entrapment syndorme (ACNES): a commonly overlooked cause of abdominal pain. Perman J. 2002;6:20–7.

    Google Scholar 

  16. Hershfield N. The abdominal wall: a frequently overlooked source of abdominal pain. J Clin Gastroenterol. 1992;14(3):199–202.

    Article  CAS  PubMed  Google Scholar 

  17. Scheltinga M, Roumen R. Anterior cutaneous nerve entrapment syndrome (ACNES). Hernia. 2018;22(3):507–16.

    Article  CAS  PubMed  Google Scholar 

  18. Applegate WV, Buckwalter NR. Microanatomy of the structures contributing to abdominal cutaneous nerve entrapment syndrome. J Am Board Fam Pract. 1997;10(5):329–32.

    CAS  PubMed  Google Scholar 

  19. Maatman RC, Kuijk SMJ, Steegers MAH, et al. A randomized controlled trial to evaluate the effect of pulsed radiofrequency as a treatment for anterior cutaneous nerve entrapment syndrome in comparison to anterior neurectomy. Pain Practice. 2019;19(7):751–61.

    Article  PubMed  Google Scholar 

  20. Boelens OBA, Scheltinga MR, Houterman S, et al. Randomized clinical trial of trigger point infiltration with lidocaine to diagnose anterior cutaneous nerve entrapment syndrome. Br J Surg. 2013;100(2):217–21.

    Article  CAS  PubMed  Google Scholar 

  21. Mol FMU, Maatman RC, De Joode, LEGH, Van Eerten P, Scheltinga MR, Roumen R. Characteristics of 1116 consecutive patients diagnosed with anterior cutaneous nerve entrapment syndrome (ACNES). Ann Surg. 2019;1–6.

  22. Carnett JB. Intercostal neuralgia as a cause of abdominal pain and tenderness. Surg Gynecol Obstet. 1926.

  23. Boelens OB, van Assen T, Houterman S, et al. A double-blind, randomized, controlled trial on surgery for chronic abdominal pain due to anterior cutaneous nerve entrapment syndrome. Ann Surg. 2013;257(5):845–9.

    Article  PubMed  Google Scholar 

  24. Mol FMU, Heukensfeldt Jansen C, Boelens OBA, et al. Adding steroids to lidocaine in a therapeutic injection regimen for patients with abdominal pain due to anterior cutaneous nerve entrapment syndrome (ACNES): a single blinded randomized clinical trial. Scand J Pain. 2018;18(3):505–12.

    Article  PubMed  Google Scholar 

  25. Boelens OBA, Scheltinga MRM, Houterman S, et al. Management of anterior cutaneous nerve entrapment syndrome in a cohort of 139 patients. Ann Surg. 2011;254(6):1054–8.

    Article  CAS  PubMed  Google Scholar 

  26. van Assen T, de Jager-Kievit JWAJ, Scheltinga MR, et al. Chronic abdominal wall pain misdiagnosed as functional abdominal pain. J Am Board Fam Med. 2013;26(6):738–44.

    Article  PubMed  Google Scholar 

  27. van Assen T, Brouns JAGM, Scheltinga MR, et al. Incidence of abdominal pain due to the anterior cutaneous nerve entrapment syndrome in an emergency department. Scand J Trauma Resusc Emerg Med. 2015;23(1):19.

    Article  PubMed  PubMed Central  Google Scholar 

  28. Pierik AS, Coblijn UK, de Raaff CAL, et al. Unexplained abdominal pain in morbidly obese patients after bariatric surgery. Surg Obes Relat Dis. 2017;13(10):1743–51.

    Article  PubMed  Google Scholar 

  29. Roumen RMH, Vening W, Wouda R, et al. Acute appendicitis, somatosensory disturbances (“head zones”), and the differential diagnosis of anterior cutaneous nerve entrapment syndrome (ACNES). J Gastrointest Surg. 2017;21(6):1055–61.

    Article  PubMed  Google Scholar 

  30. Ruiz-Tovar J, Oller I, Diez M, et al. Percutaneous electrical neurostimulation of dermatome T6 for appetite reduction and weight loss in morbidly obese patients. Obes Surg. 2014;24(2):205–11.

    Article  PubMed  Google Scholar 

  31. Ruiz-Tovar J, Llavero C, Smith W. Percutaneous electrical neurostimulation of dermatome T6 for short-term weight loss in overweight and obese patients: effect on ghrelin levels, glucose, lipid, and hormonal profile. Surg Laparosc Endosc Percutan Tech. 2017;27(4):241–7.

    Article  PubMed  Google Scholar 

  32. Hansen K, Schliack H. Segmentale Innervation: Ihre Bedeutung fur Klinik und Praxis. Neurology. 1963;13(5):443.

    Google Scholar 

  33. Giamberardino M, Vecchiet L. Pathophysiology of visceral pain. Curr Pain Headache Rep. 1997;1(1):23–33.

    Article  Google Scholar 

  34. Al Harakeh A, Kallies KJ, Borgert AJ, et al. Bowel obstruction rates in antecolic/antegastric versus retrocolic/retrogastric Roux limb gastric bypass: a meta-analysis. Surg Obes Relat Dis. 2016;12(1):194–8.

    Article  PubMed  Google Scholar 

  35. Elms L, Moon R, Varnadore S, et al. Causes of small bowel obstruction after Roux-en-Y gastric bypass: a review of 2,395 cases at a single institution. Surg Endosc. 2014;28(5):1624–8.

    Article  PubMed  Google Scholar 

  36. Sanyal AJ, Sugerman HJ, Kellum JM, et al. Stomal complications of gastric bypass: incidence and outcome of therapy. Am J Gastroenterol. 1992;87(9):1165–9.

    CAS  PubMed  Google Scholar 

  37. Nguyen NT, Goldman C, Rosenquist CJ, et al. Laparoscopic versus open gastric bypass: a randomized study of outcomes, quality of life, and costs. Ann Surg. 2001 Sep;234(3):279–91.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  38. Wittgrove A, Clark G. Laparoscopic gastric bypass, Roux en-Y - 500 patients: technique and results, with 3-60 month follow-up. Obes Surg. 2000;10(3):233–9.

    Article  CAS  PubMed  Google Scholar 

  39. Stenberg E, Szabo E, Ågren G, et al. Closure of mesenteric defects in laparoscopic gastric bypass: a multicentre, randomised, parallel, open-label trial. Lancet. 2016 Apr;387(10026):1397–404.

    Article  PubMed  Google Scholar 

Download references

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Correspondence to Monica L. Y. E. Jacobs.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Jansen, C.M.A.H., Bonouvrie, D.S., Jacobs, M.L.Y.E. et al. Chronic Abdominal Pain After Previous Bariatric Surgery: Consider the Abdominal Wall. OBES SURG 30, 2942–2948 (2020). https://doi.org/10.1007/s11695-020-04629-7

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  • DOI: https://doi.org/10.1007/s11695-020-04629-7

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